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Oral co-exposure to Clostridioides difficile toxin A and ovalbumin disrupts intestinal homeostasis and predisposes to food allergy in mice.

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Title: Oral co-exposure to Clostridioides difficile toxin A and ovalbumin disrupts intestinal homeostasis and predisposes to food allergy in mice.
Authors: Xu X; State Key Laboratory of Food Science and Resources, Nanchang University, Nanchang, 330047, PR China; College of Food Science & Technology, Nanchang University, Nanchang, 330031, PR China; Jiangxi Province Key Laboratory of Food Allergy, Nanchang, 330047, PR China; Jiangxi Province Engineering Research Center of Special Medical Purposes Intended for Allergic Population, PR China., Zeng X; State Key Laboratory of Food Science and Resources, Nanchang University, Nanchang, 330047, PR China; College of Food Science & Technology, Nanchang University, Nanchang, 330031, PR China; Jiangxi Province Key Laboratory of Food Allergy, Nanchang, 330047, PR China; Jiangxi Province Engineering Research Center of Special Medical Purposes Intended for Allergic Population, PR China., Cheng Y; State Key Laboratory of Food Science and Resources, Nanchang University, Nanchang, 330047, PR China; College of Food Science & Technology, Nanchang University, Nanchang, 330031, PR China; Jiangxi Province Key Laboratory of Food Allergy, Nanchang, 330047, PR China; Jiangxi Province Engineering Research Center of Special Medical Purposes Intended for Allergic Population, PR China., Yang P; State Key Laboratory of Food Science and Resources, Nanchang University, Nanchang, 330047, PR China; College of Food Science & Technology, Nanchang University, Nanchang, 330031, PR China; Jiangxi Province Key Laboratory of Food Allergy, Nanchang, 330047, PR China; Jiangxi Province Engineering Research Center of Special Medical Purposes Intended for Allergic Population, PR China., Gao J; State Key Laboratory of Food Science and Resources, Nanchang University, Nanchang, 330047, PR China; College of Food Science & Technology, Nanchang University, Nanchang, 330031, PR China; Jiangxi Province Key Laboratory of Food Allergy, Nanchang, 330047, PR China; Jiangxi Province Engineering Research Center of Special Medical Purposes Intended for Allergic Population, PR China., Meng X; State Key Laboratory of Food Science and Resources, Nanchang University, Nanchang, 330047, PR China; Sino-German Joint Research Institute, Nanchang University, Nanchang, 330047, PR China; Jiangxi Province Key Laboratory of Food Allergy, Nanchang, 330047, PR China; Jiangxi Province Engineering Research Center of Special Medical Purposes Intended for Allergic Population, PR China., Wu Y; State Key Laboratory of Food Science and Resources, Nanchang University, Nanchang, 330047, PR China; Sino-German Joint Research Institute, Nanchang University, Nanchang, 330047, PR China; Jiangxi Province Key Laboratory of Food Allergy, Nanchang, 330047, PR China; Jiangxi Province Engineering Research Center of Special Medical Purposes Intended for Allergic Population, PR China., Li X; State Key Laboratory of Food Science and Resources, Nanchang University, Nanchang, 330047, PR China; College of Food Science & Technology, Nanchang University, Nanchang, 330031, PR China; Jiangxi Province Key Laboratory of Food Allergy, Nanchang, 330047, PR China; Jiangxi Province Engineering Research Center of Special Medical Purposes Intended for Allergic Population, PR China., Tong P; State Key Laboratory of Food Science and Resources, Nanchang University, Nanchang, 330047, PR China; Jiangxi Province Key Laboratory of Food Allergy, Nanchang, 330047, PR China; Jiangxi Province Engineering Research Center of Special Medical Purposes Intended for Allergic Population, PR China. Electronic address: tongping@ncu.edu.cn., Chen H; State Key Laboratory of Food Science and Resources, Nanchang University, Nanchang, 330047, PR China; Sino-German Joint Research Institute, Nanchang University, Nanchang, 330047, PR China; Jiangxi Province Key Laboratory of Food Allergy, Nanchang, 330047, PR China; Jiangxi Province Engineering Research Center of Special Medical Purposes Intended for Allergic Population, PR China. Electronic address: chenhongbing@ncu.edu.cn.
Source: Toxicon : official journal of the International Society on Toxinology [Toxicon] 2026 Jun 01; Vol. 275, pp. 109052. Date of Electronic Publication: 2026 Mar 04.
Publication Type: Journal Article
Journal Info: Publisher: Pergamon Press Country of Publication: England NLM ID: 1307333 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-3150 (Electronic) Linking ISSN: 00410101 NLM ISO Abbreviation: Toxicon Subsets: MEDLINE
Database: MEDLINE Ultimate
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PubType: Academic Journal
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  Data: Oral co-exposure to Clostridioides difficile toxin A and ovalbumin disrupts intestinal homeostasis and predisposes to food allergy in mice.
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  Data: <searchLink fieldCode="AU" term="%22Xu+X%22">Xu X</searchLink>; State Key Laboratory of Food Science and Resources, Nanchang University, Nanchang, 330047, PR China; College of Food Science & Technology, Nanchang University, Nanchang, 330031, PR China; Jiangxi Province Key Laboratory of Food Allergy, Nanchang, 330047, PR China; Jiangxi Province Engineering Research Center of Special Medical Purposes Intended for Allergic Population, PR China.<br /><searchLink fieldCode="AU" term="%22Zeng+X%22">Zeng X</searchLink>; State Key Laboratory of Food Science and Resources, Nanchang University, Nanchang, 330047, PR China; College of Food Science & Technology, Nanchang University, Nanchang, 330031, PR China; Jiangxi Province Key Laboratory of Food Allergy, Nanchang, 330047, PR China; Jiangxi Province Engineering Research Center of Special Medical Purposes Intended for Allergic Population, PR China.<br /><searchLink fieldCode="AU" term="%22Cheng+Y%22">Cheng Y</searchLink>; State Key Laboratory of Food Science and Resources, Nanchang University, Nanchang, 330047, PR China; College of Food Science & Technology, Nanchang University, Nanchang, 330031, PR China; Jiangxi Province Key Laboratory of Food Allergy, Nanchang, 330047, PR China; Jiangxi Province Engineering Research Center of Special Medical Purposes Intended for Allergic Population, PR China.<br /><searchLink fieldCode="AU" term="%22Yang+P%22">Yang P</searchLink>; State Key Laboratory of Food Science and Resources, Nanchang University, Nanchang, 330047, PR China; College of Food Science & Technology, Nanchang University, Nanchang, 330031, PR China; Jiangxi Province Key Laboratory of Food Allergy, Nanchang, 330047, PR China; Jiangxi Province Engineering Research Center of Special Medical Purposes Intended for Allergic Population, PR China.<br /><searchLink fieldCode="AU" term="%22Gao+J%22">Gao J</searchLink>; State Key Laboratory of Food Science and Resources, Nanchang University, Nanchang, 330047, PR China; College of Food Science & Technology, Nanchang University, Nanchang, 330031, PR China; Jiangxi Province Key Laboratory of Food Allergy, Nanchang, 330047, PR China; Jiangxi Province Engineering Research Center of Special Medical Purposes Intended for Allergic Population, PR China.<br /><searchLink fieldCode="AU" term="%22Meng+X%22">Meng X</searchLink>; State Key Laboratory of Food Science and Resources, Nanchang University, Nanchang, 330047, PR China; Sino-German Joint Research Institute, Nanchang University, Nanchang, 330047, PR China; Jiangxi Province Key Laboratory of Food Allergy, Nanchang, 330047, PR China; Jiangxi Province Engineering Research Center of Special Medical Purposes Intended for Allergic Population, PR China.<br /><searchLink fieldCode="AU" term="%22Wu+Y%22">Wu Y</searchLink>; State Key Laboratory of Food Science and Resources, Nanchang University, Nanchang, 330047, PR China; Sino-German Joint Research Institute, Nanchang University, Nanchang, 330047, PR China; Jiangxi Province Key Laboratory of Food Allergy, Nanchang, 330047, PR China; Jiangxi Province Engineering Research Center of Special Medical Purposes Intended for Allergic Population, PR China.<br /><searchLink fieldCode="AU" term="%22Li+X%22">Li X</searchLink>; State Key Laboratory of Food Science and Resources, Nanchang University, Nanchang, 330047, PR China; College of Food Science & Technology, Nanchang University, Nanchang, 330031, PR China; Jiangxi Province Key Laboratory of Food Allergy, Nanchang, 330047, PR China; Jiangxi Province Engineering Research Center of Special Medical Purposes Intended for Allergic Population, PR China.<br /><searchLink fieldCode="AU" term="%22Tong+P%22">Tong P</searchLink>; State Key Laboratory of Food Science and Resources, Nanchang University, Nanchang, 330047, PR China; Jiangxi Province Key Laboratory of Food Allergy, Nanchang, 330047, PR China; Jiangxi Province Engineering Research Center of Special Medical Purposes Intended for Allergic Population, PR China. Electronic address: tongping@ncu.edu.cn.<br /><searchLink fieldCode="AU" term="%22Chen+H%22">Chen H</searchLink>; State Key Laboratory of Food Science and Resources, Nanchang University, Nanchang, 330047, PR China; Sino-German Joint Research Institute, Nanchang University, Nanchang, 330047, PR China; Jiangxi Province Key Laboratory of Food Allergy, Nanchang, 330047, PR China; Jiangxi Province Engineering Research Center of Special Medical Purposes Intended for Allergic Population, PR China. Electronic address: chenhongbing@ncu.edu.cn.
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  Data: <searchLink fieldCode="JN" term="%221307333%22">Toxicon : official journal of the International Society on Toxinology</searchLink> [Toxicon] 2026 Jun 01; Vol. 275, pp. 109052. <i>Date of Electronic Publication: </i>2026 Mar 04.
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RecordInfo BibRecord:
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      – Type: doi
        Value: 10.1016/j.toxicon.2026.109052
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      – Code: eng
        Text: English
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        StartPage: 109052
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      – TitleFull: Oral co-exposure to Clostridioides difficile toxin A and ovalbumin disrupts intestinal homeostasis and predisposes to food allergy in mice.
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            – D: 01
              M: 06
              Text: 2026 Jun 01
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              Y: 2026
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