Anti-thymocyte globulin (ATG)- or alemtuzumab-based graft-versus-host disease prophylaxis in reduced-intensity conditioning allogeneic hematopoietic cell transplantation (HCT) for patients 40 years and older with acute lymphoblastic leukemia in first complete remission: a study from the EBMT Acute Leukemia Working Party.

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Title: Anti-thymocyte globulin (ATG)- or alemtuzumab-based graft-versus-host disease prophylaxis in reduced-intensity conditioning allogeneic hematopoietic cell transplantation (HCT) for patients 40 years and older with acute lymphoblastic leukemia in first complete remission: a study from the EBMT Acute Leukemia Working Party.
Authors: Bug G; Goethe University, Department of Medicine 2, Frankfurt am Main, Germany. g.bug@em.uni-frankfurt.de., Labopin M; Sorbonne University, Department of Hematology, Saint Antoine Hospital, INSERM, Paris, France., Byrne JL; Nottingham University Hospitals Trust, Nottingham, UK., Mielke S; Department of Cellular Therapies and Allogeneic Stem Cell Transplantation (CAST), Karolinska CCC and ATMP Center, Stockholm, Sweden., Orchard K; Wessex Blood and Marrow Transplantation and Cellular Therapy, Dept of Haematology, University Hospital Southampton NHSFT, Southampton, UK., Paneesha S; University Hospitals Birmingham NHS Foundation Trust, Queen Elizabeth Medical Centre, Edgbaston, Dept. of Haematology, Birmingham, UK., Potter V; Kings College Hospital, Dept. of Haematological Medicine, King's Denmark Hill Campus, London, UK., Blaise D; Transplantation and Cellular Immunotherapy, Department of Hematology, Institut Paoli Calmettes, Management Sport Cancer Lab, Aix Marseille University, Marseille, France., Besley C; University Hospitals Bristol and Weston NHSFT, Bristol, UK., Snowden JA; Department of Haematology, Sheffield Teaching Hospitals NHS Trust, Sheffield, UK.; Division of Clinical Medicine, School of Medicine and Population Health, The University of Sheffield, Sheffield, UK., Yakoub-Agha I; CHU de Lille, Univ de Lille, INSERM, Lille, France., Clark A; Bone Marrow Transplant Unit, Beatson, West of Scotland Cancer Centre, Glasgow, UK., Crawley C; Department of Haematology, Addenbrookes Hospital, Cambridge, UK., Spyridonidis A; Bone Marrow Transplantation Unit and Institute of Cellular Therapy, University of Patras, Patras, Greece., Sanz J; Hematology, University Hospital La Fe, Madrid, Spain., Brissot E; Sorbonne University, Department of Hematology, Saint Antoine Hospital, INSERM, Paris, France., Giebel S; Maria Sklodowska-Curie National Research Institute of Oncology, Gliwice Branch, Gliwice, Poland., Ciceri F; Hematology and Bone Marrow Transplant Unit, IRCCS San Raffaele Scientific Institute, Milan, Italy., Mohty M; Sorbonne University, Department of Hematology, Saint Antoine Hospital, INSERM, Paris, France.
Source: Bone marrow transplantation [Bone Marrow Transplant] 2026 Apr; Vol. 61 (4), pp. 462-468. Date of Electronic Publication: 2026 Mar 06.
Publication Type: Journal Article
Journal Info: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 8702459 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-5365 (Electronic) Linking ISSN: 02683369 NLM ISO Abbreviation: Bone Marrow Transplant Subsets: MEDLINE
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  Data: Anti-thymocyte globulin (ATG)- or alemtuzumab-based graft-versus-host disease prophylaxis in reduced-intensity conditioning allogeneic hematopoietic cell transplantation (HCT) for patients 40 years and older with acute lymphoblastic leukemia in first complete remission: a study from the EBMT Acute Leukemia Working Party.
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  Data: <searchLink fieldCode="AU" term="%22Bug+G%22">Bug G</searchLink>; Goethe University, Department of Medicine 2, Frankfurt am Main, Germany. g.bug@em.uni-frankfurt.de.<br /><searchLink fieldCode="AU" term="%22Labopin+M%22">Labopin M</searchLink>; Sorbonne University, Department of Hematology, Saint Antoine Hospital, INSERM, Paris, France.<br /><searchLink fieldCode="AU" term="%22Byrne+JL%22">Byrne JL</searchLink>; Nottingham University Hospitals Trust, Nottingham, UK.<br /><searchLink fieldCode="AU" term="%22Mielke+S%22">Mielke S</searchLink>; Department of Cellular Therapies and Allogeneic Stem Cell Transplantation (CAST), Karolinska CCC and ATMP Center, Stockholm, Sweden.<br /><searchLink fieldCode="AU" term="%22Orchard+K%22">Orchard K</searchLink>; Wessex Blood and Marrow Transplantation and Cellular Therapy, Dept of Haematology, University Hospital Southampton NHSFT, Southampton, UK.<br /><searchLink fieldCode="AU" term="%22Paneesha+S%22">Paneesha S</searchLink>; University Hospitals Birmingham NHS Foundation Trust, Queen Elizabeth Medical Centre, Edgbaston, Dept. of Haematology, Birmingham, UK.<br /><searchLink fieldCode="AU" term="%22Potter+V%22">Potter V</searchLink>; Kings College Hospital, Dept. of Haematological Medicine, King's Denmark Hill Campus, London, UK.<br /><searchLink fieldCode="AU" term="%22Blaise+D%22">Blaise D</searchLink>; Transplantation and Cellular Immunotherapy, Department of Hematology, Institut Paoli Calmettes, Management Sport Cancer Lab, Aix Marseille University, Marseille, France.<br /><searchLink fieldCode="AU" term="%22Besley+C%22">Besley C</searchLink>; University Hospitals Bristol and Weston NHSFT, Bristol, UK.<br /><searchLink fieldCode="AU" term="%22Snowden+JA%22">Snowden JA</searchLink>; Department of Haematology, Sheffield Teaching Hospitals NHS Trust, Sheffield, UK.; Division of Clinical Medicine, School of Medicine and Population Health, The University of Sheffield, Sheffield, UK.<br /><searchLink fieldCode="AU" term="%22Yakoub-Agha+I%22">Yakoub-Agha I</searchLink>; CHU de Lille, Univ de Lille, INSERM, Lille, France.<br /><searchLink fieldCode="AU" term="%22Clark+A%22">Clark A</searchLink>; Bone Marrow Transplant Unit, Beatson, West of Scotland Cancer Centre, Glasgow, UK.<br /><searchLink fieldCode="AU" term="%22Crawley+C%22">Crawley C</searchLink>; Department of Haematology, Addenbrookes Hospital, Cambridge, UK.<br /><searchLink fieldCode="AU" term="%22Spyridonidis+A%22">Spyridonidis A</searchLink>; Bone Marrow Transplantation Unit and Institute of Cellular Therapy, University of Patras, Patras, Greece.<br /><searchLink fieldCode="AU" term="%22Sanz+J%22">Sanz J</searchLink>; Hematology, University Hospital La Fe, Madrid, Spain.<br /><searchLink fieldCode="AU" term="%22Brissot+E%22">Brissot E</searchLink>; Sorbonne University, Department of Hematology, Saint Antoine Hospital, INSERM, Paris, France.<br /><searchLink fieldCode="AU" term="%22Giebel+S%22">Giebel S</searchLink>; Maria Sklodowska-Curie National Research Institute of Oncology, Gliwice Branch, Gliwice, Poland.<br /><searchLink fieldCode="AU" term="%22Ciceri+F%22">Ciceri F</searchLink>; Hematology and Bone Marrow Transplant Unit, IRCCS San Raffaele Scientific Institute, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Mohty+M%22">Mohty M</searchLink>; Sorbonne University, Department of Hematology, Saint Antoine Hospital, INSERM, Paris, France.
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