A stable two-component cationic liposome platform for mRNA delivery induces CD8+ T-cell responses and protection in a murine lymphoma model.

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Title: A stable two-component cationic liposome platform for mRNA delivery induces CD8+ T-cell responses and protection in a murine lymphoma model.
Authors: Pedersen GK; Department of Infectious Disease Immunology, Center for Vaccine Research, Statens Serum Institut, Artillerivej 5, Copenhagen, 2300, Denmark.; Department of Immunology and Microbiology, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Alhakeem RS; Department of Infectious Disease Immunology, Center for Vaccine Research, Statens Serum Institut, Artillerivej 5, Copenhagen, 2300, Denmark., Tami A; Department of Infectious Disease Immunology, Center for Vaccine Research, Statens Serum Institut, Artillerivej 5, Copenhagen, 2300, Denmark., Christensen D; Department of Infectious Disease Immunology, Center for Vaccine Research, Statens Serum Institut, Artillerivej 5, Copenhagen, 2300, Denmark.; Vaccine Adjuvant Systems R&D, Croda Pharma, Lyngby, 2800, Denmark., Shabanian Z; Department of Infectious Disease Immunology, Center for Vaccine Research, Statens Serum Institut, Artillerivej 5, Copenhagen, 2300, Denmark., Jensen RF; Department of Infectious Disease Immunology, Center for Vaccine Research, Statens Serum Institut, Artillerivej 5, Copenhagen, 2300, Denmark., Wørzner K; Department of Infectious Disease Immunology, Center for Vaccine Research, Statens Serum Institut, Artillerivej 5, Copenhagen, 2300, Denmark., Schmidt ST; Department of Infectious Disease Immunology, Center for Vaccine Research, Statens Serum Institut, Artillerivej 5, Copenhagen, 2300, Denmark. sxs@ssi.dk.
Source: Journal of nanobiotechnology [J Nanobiotechnology] 2026 Mar 07; Vol. 24 (1). Date of Electronic Publication: 2026 Mar 07.
Publication Type: Journal Article
Journal Info: Publisher: BioMed Central Country of Publication: England NLM ID: 101152208 Publication Model: Electronic Cited Medium: Internet ISSN: 1477-3155 (Electronic) Linking ISSN: 14773155 NLM ISO Abbreviation: J Nanobiotechnology Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1477-3155
DOI:10.1186/s12951-026-04234-3