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A stable two-component cationic liposome platform for mRNA delivery induces CD8+ T-cell responses and protection in a murine lymphoma model.

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Title: A stable two-component cationic liposome platform for mRNA delivery induces CD8+ T-cell responses and protection in a murine lymphoma model.
Authors: Pedersen GK; Department of Infectious Disease Immunology, Center for Vaccine Research, Statens Serum Institut, Artillerivej 5, Copenhagen, 2300, Denmark.; Department of Immunology and Microbiology, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Alhakeem RS; Department of Infectious Disease Immunology, Center for Vaccine Research, Statens Serum Institut, Artillerivej 5, Copenhagen, 2300, Denmark., Tami A; Department of Infectious Disease Immunology, Center for Vaccine Research, Statens Serum Institut, Artillerivej 5, Copenhagen, 2300, Denmark., Christensen D; Department of Infectious Disease Immunology, Center for Vaccine Research, Statens Serum Institut, Artillerivej 5, Copenhagen, 2300, Denmark.; Vaccine Adjuvant Systems R&D, Croda Pharma, Lyngby, 2800, Denmark., Shabanian Z; Department of Infectious Disease Immunology, Center for Vaccine Research, Statens Serum Institut, Artillerivej 5, Copenhagen, 2300, Denmark., Jensen RF; Department of Infectious Disease Immunology, Center for Vaccine Research, Statens Serum Institut, Artillerivej 5, Copenhagen, 2300, Denmark., Wørzner K; Department of Infectious Disease Immunology, Center for Vaccine Research, Statens Serum Institut, Artillerivej 5, Copenhagen, 2300, Denmark., Schmidt ST; Department of Infectious Disease Immunology, Center for Vaccine Research, Statens Serum Institut, Artillerivej 5, Copenhagen, 2300, Denmark. sxs@ssi.dk.
Source: Journal of nanobiotechnology [J Nanobiotechnology] 2026 Mar 07; Vol. 24 (1). Date of Electronic Publication: 2026 Mar 07.
Publication Type: Journal Article
Journal Info: Publisher: BioMed Central Country of Publication: England NLM ID: 101152208 Publication Model: Electronic Cited Medium: Internet ISSN: 1477-3155 (Electronic) Linking ISSN: 14773155 NLM ISO Abbreviation: J Nanobiotechnology Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: A stable two-component cationic liposome platform for mRNA delivery induces CD8<superscript>+</superscript> T-cell responses and protection in a murine lymphoma model.
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  Data: <searchLink fieldCode="AU" term="%22Pedersen+GK%22">Pedersen GK</searchLink>; Department of Infectious Disease Immunology, Center for Vaccine Research, Statens Serum Institut, Artillerivej 5, Copenhagen, 2300, Denmark.; Department of Immunology and Microbiology, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.<br /><searchLink fieldCode="AU" term="%22Alhakeem+RS%22">Alhakeem RS</searchLink>; Department of Infectious Disease Immunology, Center for Vaccine Research, Statens Serum Institut, Artillerivej 5, Copenhagen, 2300, Denmark.<br /><searchLink fieldCode="AU" term="%22Tami+A%22">Tami A</searchLink>; Department of Infectious Disease Immunology, Center for Vaccine Research, Statens Serum Institut, Artillerivej 5, Copenhagen, 2300, Denmark.<br /><searchLink fieldCode="AU" term="%22Christensen+D%22">Christensen D</searchLink>; Department of Infectious Disease Immunology, Center for Vaccine Research, Statens Serum Institut, Artillerivej 5, Copenhagen, 2300, Denmark.; Vaccine Adjuvant Systems R&D, Croda Pharma, Lyngby, 2800, Denmark.<br /><searchLink fieldCode="AU" term="%22Shabanian+Z%22">Shabanian Z</searchLink>; Department of Infectious Disease Immunology, Center for Vaccine Research, Statens Serum Institut, Artillerivej 5, Copenhagen, 2300, Denmark.<br /><searchLink fieldCode="AU" term="%22Jensen+RF%22">Jensen RF</searchLink>; Department of Infectious Disease Immunology, Center for Vaccine Research, Statens Serum Institut, Artillerivej 5, Copenhagen, 2300, Denmark.<br /><searchLink fieldCode="AU" term="%22Wørzner+K%22">Wørzner K</searchLink>; Department of Infectious Disease Immunology, Center for Vaccine Research, Statens Serum Institut, Artillerivej 5, Copenhagen, 2300, Denmark.<br /><searchLink fieldCode="AU" term="%22Schmidt+ST%22">Schmidt ST</searchLink>; Department of Infectious Disease Immunology, Center for Vaccine Research, Statens Serum Institut, Artillerivej 5, Copenhagen, 2300, Denmark. sxs@ssi.dk.
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  Data: <searchLink fieldCode="JN" term="%22101152208%22">Journal of nanobiotechnology</searchLink> [J Nanobiotechnology] 2026 Mar 07; Vol. 24 (1). <i>Date of Electronic Publication: </i>2026 Mar 07.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22BioMed+Central%22">BioMed Central </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>101152208 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1477-3155 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2214773155%22">14773155 </searchLink><i>NLM ISO Abbreviation: </i>J Nanobiotechnology <i>Subsets: </i>MEDLINE
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        Value: 10.1186/s12951-026-04234-3
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      – Code: eng
        Text: English
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      – TitleFull: A stable two-component cationic liposome platform for mRNA delivery induces CD8+ T-cell responses and protection in a murine lymphoma model.
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              Text: 2026 Mar 07
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