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Reovirus resistance in tumors mediated by elevated ISG expression: overcoming therapeutic resistance via JAK/STAT pathway modulation.

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Title: Reovirus resistance in tumors mediated by elevated ISG expression: overcoming therapeutic resistance via JAK/STAT pathway modulation.
Authors: Yang Y; Center for Tissue Engineering and Stem Cell Research, Guizhou Medical University, Guiyang, Guizhou, China.; Department of Immunology, Basic Medical College, Guizhou Medical University, Guiyang, Guizhou, China., Lin X; Center for Tissue Engineering and Stem Cell Research, Guizhou Medical University, Guiyang, Guizhou, China.; Department of Cell Biology, Basic Medical College, Guizhou Medical University, Guiyang, Guizhou, China., Chen L; Thoracic and Breast Surgery Department, Anshun People's Hospital, Anshun, Guizhou, China., Fan Y; Department of Immunology, Basic Medical College, Guizhou Medical University, Guiyang, Guizhou, China., Dou X; Clinical Research Center, The Affiliated Hospital of Guizhou Medical University, Guiyang, Guizhou, China., Zhang J; Department of Cell Biology, Basic Medical College, Guizhou Medical University, Guiyang, Guizhou, China., Zhang Y; Department of Cell Biology, Basic Medical College, Guizhou Medical University, Guiyang, Guizhou, China., Liang D; Center for Tissue Engineering and Stem Cell Research, Guizhou Medical University, Guiyang, Guizhou, China.; Department of Immunology, Basic Medical College, Guizhou Medical University, Guiyang, Guizhou, China., Zhao X; Center for Tissue Engineering and Stem Cell Research, Guizhou Medical University, Guiyang, Guizhou, China. xingzhao@gmc.edu.cn.; Department of Immunology, Basic Medical College, Guizhou Medical University, Guiyang, Guizhou, China. xingzhao@gmc.edu.cn.
Source: Virology journal [Virol J] 2026 Mar 06; Vol. 23 (1). Date of Electronic Publication: 2026 Mar 06.
Publication Type: Journal Article
Journal Info: Publisher: BioMed Central Country of Publication: England NLM ID: 101231645 Publication Model: Electronic Cited Medium: Internet ISSN: 1743-422X (Electronic) Linking ISSN: 1743422X NLM ISO Abbreviation: Virol J Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Reovirus resistance in tumors mediated by elevated ISG expression: overcoming therapeutic resistance via JAK/STAT pathway modulation.
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  Data: <searchLink fieldCode="AU" term="%22Yang+Y%22">Yang Y</searchLink>; Center for Tissue Engineering and Stem Cell Research, Guizhou Medical University, Guiyang, Guizhou, China.; Department of Immunology, Basic Medical College, Guizhou Medical University, Guiyang, Guizhou, China.<br /><searchLink fieldCode="AU" term="%22Lin+X%22">Lin X</searchLink>; Center for Tissue Engineering and Stem Cell Research, Guizhou Medical University, Guiyang, Guizhou, China.; Department of Cell Biology, Basic Medical College, Guizhou Medical University, Guiyang, Guizhou, China.<br /><searchLink fieldCode="AU" term="%22Chen+L%22">Chen L</searchLink>; Thoracic and Breast Surgery Department, Anshun People's Hospital, Anshun, Guizhou, China.<br /><searchLink fieldCode="AU" term="%22Fan+Y%22">Fan Y</searchLink>; Department of Immunology, Basic Medical College, Guizhou Medical University, Guiyang, Guizhou, China.<br /><searchLink fieldCode="AU" term="%22Dou+X%22">Dou X</searchLink>; Clinical Research Center, The Affiliated Hospital of Guizhou Medical University, Guiyang, Guizhou, China.<br /><searchLink fieldCode="AU" term="%22Zhang+J%22">Zhang J</searchLink>; Department of Cell Biology, Basic Medical College, Guizhou Medical University, Guiyang, Guizhou, China.<br /><searchLink fieldCode="AU" term="%22Zhang+Y%22">Zhang Y</searchLink>; Department of Cell Biology, Basic Medical College, Guizhou Medical University, Guiyang, Guizhou, China.<br /><searchLink fieldCode="AU" term="%22Liang+D%22">Liang D</searchLink>; Center for Tissue Engineering and Stem Cell Research, Guizhou Medical University, Guiyang, Guizhou, China.; Department of Immunology, Basic Medical College, Guizhou Medical University, Guiyang, Guizhou, China.<br /><searchLink fieldCode="AU" term="%22Zhao+X%22">Zhao X</searchLink>; Center for Tissue Engineering and Stem Cell Research, Guizhou Medical University, Guiyang, Guizhou, China. xingzhao@gmc.edu.cn.; Department of Immunology, Basic Medical College, Guizhou Medical University, Guiyang, Guizhou, China. xingzhao@gmc.edu.cn.
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  Data: <searchLink fieldCode="JN" term="%22101231645%22">Virology journal</searchLink> [Virol J] 2026 Mar 06; Vol. 23 (1). <i>Date of Electronic Publication: </i>2026 Mar 06.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22BioMed+Central%22">BioMed Central </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>101231645 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1743-422X (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%221743422X%22">1743422X </searchLink><i>NLM ISO Abbreviation: </i>Virol J <i>Subsets: </i>MEDLINE
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        Value: 10.1186/s12985-026-03118-0
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        Text: English
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      – TitleFull: Reovirus resistance in tumors mediated by elevated ISG expression: overcoming therapeutic resistance via JAK/STAT pathway modulation.
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              Text: 2026 Mar 06
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