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Epigenome-wide analysis in West Africans identifies DNA methylation markers for circulating adiponectin.

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Title: Epigenome-wide analysis in West Africans identifies DNA methylation markers for circulating adiponectin.
Authors: Mungamba MM; Department of Public and Occupational Health, Amsterdam University Medical Centers, University of Amsterdam, Amsterdam Public Health Research Institute, Amsterdam, the Netherlands; Department of Human Biology, Faculty of Medicine and Health Sciences, Walter Sisulu University, Mthatha, South Africa. Electronic address: m.m.mungamba@amsterdamumc.nl., Wijburg J; Department of Public and Occupational Health, Amsterdam University Medical Centers, University of Amsterdam, Amsterdam Public Health Research Institute, Amsterdam, the Netherlands., van der Linden EL; Department of Public and Occupational Health, Amsterdam University Medical Centers, University of Amsterdam, Amsterdam Public Health Research Institute, Amsterdam, the Netherlands., Chilunga FP; Department of Public and Occupational Health, Amsterdam University Medical Centers, University of Amsterdam, Amsterdam Public Health Research Institute, Amsterdam, the Netherlands., Doumatey AP; Center for Research on Genomics and Global Health, National Human Genome Research Institute, National Institutes of Health, Bethesda, MD, USA., Bentley AR; Center for Research on Genomics and Global Health, National Human Genome Research Institute, National Institutes of Health, Bethesda, MD, USA., Hayfron-Benjamin CF; Department of Public and Occupational Health, Amsterdam University Medical Centers, University of Amsterdam, Amsterdam Public Health Research Institute, Amsterdam, the Netherlands; Department of Vascular Medicine, Amsterdam University Medical Centers, University of Amsterdam, Amsterdam Cardiovascular Sciences, Amsterdam, the Netherlands; Departments of Physiology and Anaesthesia/Critical Care, University of Ghana Medical School, Korle Bu Teaching Hospital, Ghana., Sewani-Rusike CR; Department of Human Biology, Faculty of Medicine and Health Sciences, Walter Sisulu University, Mthatha, South Africa., Nkeh-Chungag BN; Department of Biological and Environmental Sciences, Faculty of Natural Sciences, Walter Sisulu University, Mthatha, South Africa., Ahima RS; Center for Research on Genomics and Global Health, National Human Genome Research Institute, National Institutes of Health, Bethesda, MD, USA., Agyemang C; Department of Public and Occupational Health, Amsterdam University Medical Centers, University of Amsterdam, Amsterdam Public Health Research Institute, Amsterdam, the Netherlands; Division of Endocrinology, Diabetes and Metabolism, Department of Medicine, The Johns Hopkins University School of Medicine, Baltimore, MD, USA., Henneman P; Department of Human Genetics, Epigenetics, Amsterdam Reproduction and Development, Research Institute, Amsterdam University Medical Centers, Amsterdam, the Netherlands., Adeyemo AA; Center for Research on Genomics and Global Health, National Human Genome Research Institute, National Institutes of Health, Bethesda, MD, USA., Rotimi CN; Center for Research on Genomics and Global Health, National Human Genome Research Institute, National Institutes of Health, Bethesda, MD, USA., Meeks KAC; Department of Public and Occupational Health, Amsterdam University Medical Centers, University of Amsterdam, Amsterdam Public Health Research Institute, Amsterdam, the Netherlands; Center for Research on Genomics and Global Health, National Human Genome Research Institute, National Institutes of Health, Bethesda, MD, USA; Division of Endocrinology, Diabetes and Nutrition, Department of Medicine, University of Maryland School of Medicine, Baltimore, MD, USA. Electronic address: karlijn.meeks@som.umaryland.edu.
Source: EBioMedicine [EBioMedicine] 2026 Apr; Vol. 126, pp. 106192. Date of Electronic Publication: 2026 Mar 06.
Publication Type: Journal Article
Journal Info: Publisher: Elsevier B.V Country of Publication: Netherlands NLM ID: 101647039 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2352-3964 (Electronic) Linking ISSN: 23523964 NLM ISO Abbreviation: EBioMedicine Subsets: MEDLINE
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  Data: Epigenome-wide analysis in West Africans identifies DNA methylation markers for circulating adiponectin.
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  Data: <searchLink fieldCode="AU" term="%22Mungamba+MM%22">Mungamba MM</searchLink>; Department of Public and Occupational Health, Amsterdam University Medical Centers, University of Amsterdam, Amsterdam Public Health Research Institute, Amsterdam, the Netherlands; Department of Human Biology, Faculty of Medicine and Health Sciences, Walter Sisulu University, Mthatha, South Africa. Electronic address: m.m.mungamba@amsterdamumc.nl.<br /><searchLink fieldCode="AU" term="%22Wijburg+J%22">Wijburg J</searchLink>; Department of Public and Occupational Health, Amsterdam University Medical Centers, University of Amsterdam, Amsterdam Public Health Research Institute, Amsterdam, the Netherlands.<br /><searchLink fieldCode="AU" term="%22van+der+Linden+EL%22">van der Linden EL</searchLink>; Department of Public and Occupational Health, Amsterdam University Medical Centers, University of Amsterdam, Amsterdam Public Health Research Institute, Amsterdam, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Chilunga+FP%22">Chilunga FP</searchLink>; Department of Public and Occupational Health, Amsterdam University Medical Centers, University of Amsterdam, Amsterdam Public Health Research Institute, Amsterdam, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Doumatey+AP%22">Doumatey AP</searchLink>; Center for Research on Genomics and Global Health, National Human Genome Research Institute, National Institutes of Health, Bethesda, MD, USA.<br /><searchLink fieldCode="AU" term="%22Bentley+AR%22">Bentley AR</searchLink>; Center for Research on Genomics and Global Health, National Human Genome Research Institute, National Institutes of Health, Bethesda, MD, USA.<br /><searchLink fieldCode="AU" term="%22Hayfron-Benjamin+CF%22">Hayfron-Benjamin CF</searchLink>; Department of Public and Occupational Health, Amsterdam University Medical Centers, University of Amsterdam, Amsterdam Public Health Research Institute, Amsterdam, the Netherlands; Department of Vascular Medicine, Amsterdam University Medical Centers, University of Amsterdam, Amsterdam Cardiovascular Sciences, Amsterdam, the Netherlands; Departments of Physiology and Anaesthesia/Critical Care, University of Ghana Medical School, Korle Bu Teaching Hospital, Ghana.<br /><searchLink fieldCode="AU" term="%22Sewani-Rusike+CR%22">Sewani-Rusike CR</searchLink>; Department of Human Biology, Faculty of Medicine and Health Sciences, Walter Sisulu University, Mthatha, South Africa.<br /><searchLink fieldCode="AU" term="%22Nkeh-Chungag+BN%22">Nkeh-Chungag BN</searchLink>; Department of Biological and Environmental Sciences, Faculty of Natural Sciences, Walter Sisulu University, Mthatha, South Africa.<br /><searchLink fieldCode="AU" term="%22Ahima+RS%22">Ahima RS</searchLink>; Center for Research on Genomics and Global Health, National Human Genome Research Institute, National Institutes of Health, Bethesda, MD, USA.<br /><searchLink fieldCode="AU" term="%22Agyemang+C%22">Agyemang C</searchLink>; Department of Public and Occupational Health, Amsterdam University Medical Centers, University of Amsterdam, Amsterdam Public Health Research Institute, Amsterdam, the Netherlands; Division of Endocrinology, Diabetes and Metabolism, Department of Medicine, The Johns Hopkins University School of Medicine, Baltimore, MD, USA.<br /><searchLink fieldCode="AU" term="%22Henneman+P%22">Henneman P</searchLink>; Department of Human Genetics, Epigenetics, Amsterdam Reproduction and Development, Research Institute, Amsterdam University Medical Centers, Amsterdam, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Adeyemo+AA%22">Adeyemo AA</searchLink>; Center for Research on Genomics and Global Health, National Human Genome Research Institute, National Institutes of Health, Bethesda, MD, USA.<br /><searchLink fieldCode="AU" term="%22Rotimi+CN%22">Rotimi CN</searchLink>; Center for Research on Genomics and Global Health, National Human Genome Research Institute, National Institutes of Health, Bethesda, MD, USA.<br /><searchLink fieldCode="AU" term="%22Meeks+KAC%22">Meeks KAC</searchLink>; Department of Public and Occupational Health, Amsterdam University Medical Centers, University of Amsterdam, Amsterdam Public Health Research Institute, Amsterdam, the Netherlands; Center for Research on Genomics and Global Health, National Human Genome Research Institute, National Institutes of Health, Bethesda, MD, USA; Division of Endocrinology, Diabetes and Nutrition, Department of Medicine, University of Maryland School of Medicine, Baltimore, MD, USA. Electronic address: karlijn.meeks@som.umaryland.edu.
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