Predicting in vivo performance of piroxicam and apalutamide drug nanocrystals from in vitro flux measurements combined with in silico modelling.

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Title: Predicting in vivo performance of piroxicam and apalutamide drug nanocrystals from in vitro flux measurements combined with in silico modelling.
Authors: Lee S; Pion Inc UK Ltd., Forest Row Business Park, Forest Row, RH18 5DW, UK., Shuddhodana; Nanoform Finland Plc, Viikinkaari 4, 00790, Helsinki, Finland., Bowdery D; Pion Inc UK Ltd., Forest Row Business Park, Forest Row, RH18 5DW, UK., Arslan A; Nanoform Finland Plc, Viikinkaari 4, 00790, Helsinki, Finland., Tsinman O; Pion Inc., 10 Cook St, Billerica, MA 01821, United States., Hæggström E; Nanoform Finland Plc, Viikinkaari 4, 00790, Helsinki, Finland., Sinkó B; Pion Inc UK Ltd., Forest Row Business Park, Forest Row, RH18 5DW, UK. Electronic address: bsinko@pion-inc.com., Danilova T; Nanoform Finland Plc, Viikinkaari 4, 00790, Helsinki, Finland. Electronic address: tatiana.danilova@helsinki.fi.
Source: International journal of pharmaceutics [Int J Pharm] 2026 Apr 10; Vol. 694, pp. 126724. Date of Electronic Publication: 2026 Mar 05.
Publication Type: Journal Article
Journal Info: Publisher: Elsevier/North-Holland Biomedical Press Country of Publication: Netherlands NLM ID: 7804127 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-3476 (Electronic) Linking ISSN: 03785173 NLM ISO Abbreviation: Int J Pharm Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Predicting in vivo performance of piroxicam and apalutamide drug nanocrystals from in vitro flux measurements combined with in silico modelling.
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  Data: <searchLink fieldCode="AU" term="%22Lee+S%22">Lee S</searchLink>; Pion Inc UK Ltd., Forest Row Business Park, Forest Row, RH18 5DW, UK.<br /><searchLink fieldCode="AU" term="%22Shuddhodana%22">Shuddhodana</searchLink>; Nanoform Finland Plc, Viikinkaari 4, 00790, Helsinki, Finland.<br /><searchLink fieldCode="AU" term="%22Bowdery+D%22">Bowdery D</searchLink>; Pion Inc UK Ltd., Forest Row Business Park, Forest Row, RH18 5DW, UK.<br /><searchLink fieldCode="AU" term="%22Arslan+A%22">Arslan A</searchLink>; Nanoform Finland Plc, Viikinkaari 4, 00790, Helsinki, Finland.<br /><searchLink fieldCode="AU" term="%22Tsinman+O%22">Tsinman O</searchLink>; Pion Inc., 10 Cook St, Billerica, MA 01821, United States.<br /><searchLink fieldCode="AU" term="%22Hæggström+E%22">Hæggström E</searchLink>; Nanoform Finland Plc, Viikinkaari 4, 00790, Helsinki, Finland.<br /><searchLink fieldCode="AU" term="%22Sinkó+B%22">Sinkó B</searchLink>; Pion Inc UK Ltd., Forest Row Business Park, Forest Row, RH18 5DW, UK. Electronic address: bsinko@pion-inc.com.<br /><searchLink fieldCode="AU" term="%22Danilova+T%22">Danilova T</searchLink>; Nanoform Finland Plc, Viikinkaari 4, 00790, Helsinki, Finland. Electronic address: tatiana.danilova@helsinki.fi.
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  Data: <searchLink fieldCode="JN" term="%227804127%22">International journal of pharmaceutics</searchLink> [Int J Pharm] 2026 Apr 10; Vol. 694, pp. 126724. <i>Date of Electronic Publication: </i>2026 Mar 05.
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        Value: 10.1016/j.ijpharm.2026.126724
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      – TitleFull: Predicting in vivo performance of piroxicam and apalutamide drug nanocrystals from in vitro flux measurements combined with in silico modelling.
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              Text: 2026 Apr 10
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