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Single-cell profiling reveals MIF-mediated immune evasion and CD8 + T cell exhaustion in relapsed multiple myeloma.

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Title: Single-cell profiling reveals MIF-mediated immune evasion and CD8 + T cell exhaustion in relapsed multiple myeloma.
Authors: Ma J; Department of Hematology and Blood and Marrow Transplantation, Tianjin Cancer Hospital Airport Hospital, National Clinical Research Center for Cancer, No. 99, Dongwu Road, Tianjin Airport Economic Zone, Tianjin, 300300, China.; Department of Hematology , Tianjin Medical University Cancer Institute & Hospital, National Clinical Research Center for Cancer, Tianjin's Clinical Research Center for Cancer, Tianjin, 300060, China., Gao S; Department of Hematology and Blood and Marrow Transplantation, Tianjin Cancer Hospital Airport Hospital, National Clinical Research Center for Cancer, No. 99, Dongwu Road, Tianjin Airport Economic Zone, Tianjin, 300300, China., Liu S; Department of Hematology and Blood and Marrow Transplantation, Tianjin Cancer Hospital Airport Hospital, National Clinical Research Center for Cancer, No. 99, Dongwu Road, Tianjin Airport Economic Zone, Tianjin, 300300, China., Chen L; Department of Hematology and Blood and Marrow Transplantation, Tianjin Cancer Hospital Airport Hospital, National Clinical Research Center for Cancer, No. 99, Dongwu Road, Tianjin Airport Economic Zone, Tianjin, 300300, China., Lin L; Department of Hematology and Blood and Marrow Transplantation, Tianjin Cancer Hospital Airport Hospital, National Clinical Research Center for Cancer, No. 99, Dongwu Road, Tianjin Airport Economic Zone, Tianjin, 300300, China., Zhang Z; Department of Hematology and Blood and Marrow Transplantation, Tianjin Cancer Hospital Airport Hospital, National Clinical Research Center for Cancer, No. 99, Dongwu Road, Tianjin Airport Economic Zone, Tianjin, 300300, China., Zhao Z; Department of Medical Oncology, Tianjin First Central Hospital, School of Medicine Nankai University, No. 24, Fukang Road, Nankai District, Tianjin, 300192, China. goodluckzho001@163.com., Li Q; Department of Hematology , Tianjin Medical University Cancer Institute & Hospital, National Clinical Research Center for Cancer, Tianjin's Clinical Research Center for Cancer, Tianjin, 300060, China. liqtj@163.com.
Source: Clinical and experimental medicine [Clin Exp Med] 2026 Mar 08; Vol. 26 (1). Date of Electronic Publication: 2026 Mar 08.
Publication Type: Journal Article
Journal Info: Publisher: Springer-Verlag Italia Country of Publication: Italy NLM ID: 100973405 Publication Model: Electronic Cited Medium: Internet ISSN: 1591-9528 (Electronic) Linking ISSN: 15918890 NLM ISO Abbreviation: Clin Exp Med Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Single-cell profiling reveals MIF-mediated immune evasion and CD8 + T cell exhaustion in relapsed multiple myeloma.
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  Data: <searchLink fieldCode="AU" term="%22Ma+J%22">Ma J</searchLink>; Department of Hematology and Blood and Marrow Transplantation, Tianjin Cancer Hospital Airport Hospital, National Clinical Research Center for Cancer, No. 99, Dongwu Road, Tianjin Airport Economic Zone, Tianjin, 300300, China.; Department of Hematology , Tianjin Medical University Cancer Institute & Hospital, National Clinical Research Center for Cancer, Tianjin's Clinical Research Center for Cancer, Tianjin, 300060, China.<br /><searchLink fieldCode="AU" term="%22Gao+S%22">Gao S</searchLink>; Department of Hematology and Blood and Marrow Transplantation, Tianjin Cancer Hospital Airport Hospital, National Clinical Research Center for Cancer, No. 99, Dongwu Road, Tianjin Airport Economic Zone, Tianjin, 300300, China.<br /><searchLink fieldCode="AU" term="%22Liu+S%22">Liu S</searchLink>; Department of Hematology and Blood and Marrow Transplantation, Tianjin Cancer Hospital Airport Hospital, National Clinical Research Center for Cancer, No. 99, Dongwu Road, Tianjin Airport Economic Zone, Tianjin, 300300, China.<br /><searchLink fieldCode="AU" term="%22Chen+L%22">Chen L</searchLink>; Department of Hematology and Blood and Marrow Transplantation, Tianjin Cancer Hospital Airport Hospital, National Clinical Research Center for Cancer, No. 99, Dongwu Road, Tianjin Airport Economic Zone, Tianjin, 300300, China.<br /><searchLink fieldCode="AU" term="%22Lin+L%22">Lin L</searchLink>; Department of Hematology and Blood and Marrow Transplantation, Tianjin Cancer Hospital Airport Hospital, National Clinical Research Center for Cancer, No. 99, Dongwu Road, Tianjin Airport Economic Zone, Tianjin, 300300, China.<br /><searchLink fieldCode="AU" term="%22Zhang+Z%22">Zhang Z</searchLink>; Department of Hematology and Blood and Marrow Transplantation, Tianjin Cancer Hospital Airport Hospital, National Clinical Research Center for Cancer, No. 99, Dongwu Road, Tianjin Airport Economic Zone, Tianjin, 300300, China.<br /><searchLink fieldCode="AU" term="%22Zhao+Z%22">Zhao Z</searchLink>; Department of Medical Oncology, Tianjin First Central Hospital, School of Medicine Nankai University, No. 24, Fukang Road, Nankai District, Tianjin, 300192, China. goodluckzho001@163.com.<br /><searchLink fieldCode="AU" term="%22Li+Q%22">Li Q</searchLink>; Department of Hematology , Tianjin Medical University Cancer Institute & Hospital, National Clinical Research Center for Cancer, Tianjin's Clinical Research Center for Cancer, Tianjin, 300060, China. liqtj@163.com.
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  Data: <searchLink fieldCode="JN" term="%22100973405%22">Clinical and experimental medicine</searchLink> [Clin Exp Med] 2026 Mar 08; Vol. 26 (1). <i>Date of Electronic Publication: </i>2026 Mar 08.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Springer-Verlag+Italia%22">Springer-Verlag Italia </searchLink><i>Country of Publication: </i>Italy <i>NLM ID: </i>100973405 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1591-9528 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2215918890%22">15918890 </searchLink><i>NLM ISO Abbreviation: </i>Clin Exp Med <i>Subsets: </i>MEDLINE
PLink https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=41795737
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      – Type: doi
        Value: 10.1007/s10238-026-02113-7
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      – Code: eng
        Text: English
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      – TitleFull: Single-cell profiling reveals MIF-mediated immune evasion and CD8 + T cell exhaustion in relapsed multiple myeloma.
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            – D: 08
              M: 03
              Text: 2026 Mar 08
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              Y: 2026
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