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Oncolytic adenoviral infection of chordoma achieves treatment efficacy associated with immunologic response and tumor microenvironmental alteration.

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Title: Oncolytic adenoviral infection of chordoma achieves treatment efficacy associated with immunologic response and tumor microenvironmental alteration.
Authors: Wu X; Department of Neurosurgery, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA., Ledbetter D; Department of Neurosurgery, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA., Tsai JW; Department of Pathology, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA., Singh S; Department of Neurosurgery, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA., Gumin J; Department of Neurosurgery, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA., Fan X; Department of Neuro-Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA., Gillard AG; Department of Neuro-Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA., Shin DH; Department of Neuro-Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA., Jiang H; Department of Neuro-Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA., Zhao B; Department of Neurosurgery, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA., Ingram D; Department of Pathology, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA., Akdemir K; Department of Neurosurgery, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA., Conley AP; Department of Sarcoma Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA., Lazar AJ; Department of Pathology, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA., Raza S; Department of Neurosurgery, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA., North R; Department of Neurosurgery, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA., Tatsui C; Department of Neurosurgery, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA., Lang FF; Department of Neurosurgery, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA., Wang WL; Department of Pathology, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA., Rhines LD; Department of Neurosurgery, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA., Gomez-Manzano C; Department of Neuro-Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA., Fueyo J; Department of Neuro-Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA., Alvarez-Breckenridge C; Department of Neurosurgery, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA.
Source: Neuro-oncology [Neuro Oncol] 2026 Jun 01; Vol. 28 (6), pp. 1458-1473.
Publication Type: Journal Article
Journal Info: Publisher: Oxford University Press Country of Publication: England NLM ID: 100887420 Publication Model: Print Cited Medium: Internet ISSN: 1523-5866 (Electronic) Linking ISSN: 15228517 NLM ISO Abbreviation: Neuro Oncol Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Oncolytic adenoviral infection of chordoma achieves treatment efficacy associated with immunologic response and tumor microenvironmental alteration.
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  Data: <searchLink fieldCode="AU" term="%22Wu+X%22">Wu X</searchLink>; Department of Neurosurgery, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA.<br /><searchLink fieldCode="AU" term="%22Ledbetter+D%22">Ledbetter D</searchLink>; Department of Neurosurgery, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA.<br /><searchLink fieldCode="AU" term="%22Tsai+JW%22">Tsai JW</searchLink>; Department of Pathology, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA.<br /><searchLink fieldCode="AU" term="%22Singh+S%22">Singh S</searchLink>; Department of Neurosurgery, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA.<br /><searchLink fieldCode="AU" term="%22Gumin+J%22">Gumin J</searchLink>; Department of Neurosurgery, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA.<br /><searchLink fieldCode="AU" term="%22Fan+X%22">Fan X</searchLink>; Department of Neuro-Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA.<br /><searchLink fieldCode="AU" term="%22Gillard+AG%22">Gillard AG</searchLink>; Department of Neuro-Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA.<br /><searchLink fieldCode="AU" term="%22Shin+DH%22">Shin DH</searchLink>; Department of Neuro-Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA.<br /><searchLink fieldCode="AU" term="%22Jiang+H%22">Jiang H</searchLink>; Department of Neuro-Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA.<br /><searchLink fieldCode="AU" term="%22Zhao+B%22">Zhao B</searchLink>; Department of Neurosurgery, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA.<br /><searchLink fieldCode="AU" term="%22Ingram+D%22">Ingram D</searchLink>; Department of Pathology, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA.<br /><searchLink fieldCode="AU" term="%22Akdemir+K%22">Akdemir K</searchLink>; Department of Neurosurgery, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA.<br /><searchLink fieldCode="AU" term="%22Conley+AP%22">Conley AP</searchLink>; Department of Sarcoma Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA.<br /><searchLink fieldCode="AU" term="%22Lazar+AJ%22">Lazar AJ</searchLink>; Department of Pathology, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA.<br /><searchLink fieldCode="AU" term="%22Raza+S%22">Raza S</searchLink>; Department of Neurosurgery, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA.<br /><searchLink fieldCode="AU" term="%22North+R%22">North R</searchLink>; Department of Neurosurgery, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA.<br /><searchLink fieldCode="AU" term="%22Tatsui+C%22">Tatsui C</searchLink>; Department of Neurosurgery, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA.<br /><searchLink fieldCode="AU" term="%22Lang+FF%22">Lang FF</searchLink>; Department of Neurosurgery, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA.<br /><searchLink fieldCode="AU" term="%22Wang+WL%22">Wang WL</searchLink>; Department of Pathology, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA.<br /><searchLink fieldCode="AU" term="%22Rhines+LD%22">Rhines LD</searchLink>; Department of Neurosurgery, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA.<br /><searchLink fieldCode="AU" term="%22Gomez-Manzano+C%22">Gomez-Manzano C</searchLink>; Department of Neuro-Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA.<br /><searchLink fieldCode="AU" term="%22Fueyo+J%22">Fueyo J</searchLink>; Department of Neuro-Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA.<br /><searchLink fieldCode="AU" term="%22Alvarez-Breckenridge+C%22">Alvarez-Breckenridge C</searchLink>; Department of Neurosurgery, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA.
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  Data: <searchLink fieldCode="JN" term="%22100887420%22">Neuro-oncology</searchLink> [Neuro Oncol] 2026 Jun 01; Vol. 28 (6), pp. 1458-1473.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Oxford+University+Press%22">Oxford University Press </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>100887420 <i>Publication Model: </i>Print <i>Cited Medium: </i>Internet <i>ISSN: </i>1523-5866 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2215228517%22">15228517 </searchLink><i>NLM ISO Abbreviation: </i>Neuro Oncol <i>Subsets: </i>MEDLINE
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              Text: 2026 Jun 01
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