Safety, tolerability, and preliminary efficacy of seltorexant versus quetiapine extended release as adjunctive therapy in major depressive disorder: a randomized, flexible-dose, 6-month, parallel-group, exploratory study.
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| Title: | Safety, tolerability, and preliminary efficacy of seltorexant versus quetiapine extended release as adjunctive therapy in major depressive disorder: a randomized, flexible-dose, 6-month, parallel-group, exploratory study. |
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| Authors: | Pinter C; Neuroscience Clinical Development, Johnson & Johnson, Titusville, NJ, United States., Thase ME; Department of Psychiatry, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, United States.; Mood & Anxiety Disorders Section, Corporal Michael J. Crescenz Veterans Affairs Medical Center, Philadelphia, PA, United States., McIntyre RS; Department of Psychiatry, University of Toronto, Toronto, ON, Canada.; Department of Pharmacology and Toxicology, University of Toronto, Toronto, ON, Canada., Cooper K; Department of Statistics & Decision Sciences, Johnson & Johnson, Spring House, PA, United States., Xu H; Department of Statistics & Decision Sciences, Johnson & Johnson, Titusville, NJ, United States., Pandina G; Neuroscience Clinical Development, Johnson & Johnson, Titusville, NJ, United States., Savitz A; Neuroscience Clinical Development, Johnson & Johnson, Titusville, NJ, United States., Drevets WC; Neuroscience Clinical Development, Johnson & Johnson, San Diego, CA, United States. |
| Source: | The international journal of neuropsychopharmacology [Int J Neuropsychopharmacol] 2026 Apr 06; Vol. 29 (4). |
| Publication Type: | Journal Article; Randomized Controlled Trial; Multicenter Study; Clinical Trial, Phase II; Comparative Study |
| Journal Info: | Publisher: Oxford University Press Country of Publication: England NLM ID: 9815893 Publication Model: Print Cited Medium: Internet ISSN: 1469-5111 (Electronic) Linking ISSN: 14611457 NLM ISO Abbreviation: Int J Neuropsychopharmacol Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 1469-5111 |
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| DOI: | 10.1093/ijnp/pyag009 |
