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Multi-omics analysis reveals CXCL14+ inhibitory neuron dysfunction in major depressive disorder.

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Title: Multi-omics analysis reveals CXCL14+ inhibitory neuron dysfunction in major depressive disorder.
Authors: Zhang L; Department of Psychiatry, Renmin Hospital of Wuhan University, Wuhan, China., Duan H; Department of Psychiatry, Renmin Hospital of Wuhan University, Wuhan, China., Lyu H; Department of Psychiatry, Renmin Hospital of Wuhan University, Wuhan, China., Ma S; Department of Psychiatry, Renmin Hospital of Wuhan University, Wuhan, China., Xu Y; Department of Dermatology, The Third Affiliated Hospital of Sun Yat-Sen University, 600 Tianhe Road, Guangzhou, China., Xie X; Department of Psychiatry, Renmin Hospital of Wuhan University, Wuhan, China; Department of Psychiatry, School of Clinical Medicine, University of Cambridge, United Kingdom., Gong Q; Department of Psychiatry, Renmin Hospital of Wuhan University, Wuhan, China., Kang L; Department of Psychiatry, Renmin Hospital of Wuhan University, Wuhan, China., Chen S; Department of Psychiatry, Renmin Hospital of Wuhan University, Wuhan, China., Liu Z; Department of Psychiatry, Renmin Hospital of Wuhan University, Wuhan, China; Taikang Center for Life and Medical Sciences, Wuhan University, Wuhan, China; State Key Laboratory of Metabolism and Regulation in Complex Organisms, College of Life Sciences, Wuhan University, Wuhan, China. Electronic address: zcliu6@whu.edu.cn.
Source: Journal of affective disorders [J Affect Disord] 2026 Jul 15; Vol. 405, pp. 121586. Date of Electronic Publication: 2026 Mar 06.
Publication Type: Journal Article
Journal Info: Publisher: Elsevier/North-Holland Biomedical Press Country of Publication: Netherlands NLM ID: 7906073 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1573-2517 (Electronic) Linking ISSN: 01650327 NLM ISO Abbreviation: J Affect Disord Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Multi-omics analysis reveals CXCL14<superscript>+</superscript> inhibitory neuron dysfunction in major depressive disorder.
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  Data: <searchLink fieldCode="AU" term="%22Zhang+L%22">Zhang L</searchLink>; Department of Psychiatry, Renmin Hospital of Wuhan University, Wuhan, China.<br /><searchLink fieldCode="AU" term="%22Duan+H%22">Duan H</searchLink>; Department of Psychiatry, Renmin Hospital of Wuhan University, Wuhan, China.<br /><searchLink fieldCode="AU" term="%22Lyu+H%22">Lyu H</searchLink>; Department of Psychiatry, Renmin Hospital of Wuhan University, Wuhan, China.<br /><searchLink fieldCode="AU" term="%22Ma+S%22">Ma S</searchLink>; Department of Psychiatry, Renmin Hospital of Wuhan University, Wuhan, China.<br /><searchLink fieldCode="AU" term="%22Xu+Y%22">Xu Y</searchLink>; Department of Dermatology, The Third Affiliated Hospital of Sun Yat-Sen University, 600 Tianhe Road, Guangzhou, China.<br /><searchLink fieldCode="AU" term="%22Xie+X%22">Xie X</searchLink>; Department of Psychiatry, Renmin Hospital of Wuhan University, Wuhan, China; Department of Psychiatry, School of Clinical Medicine, University of Cambridge, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Gong+Q%22">Gong Q</searchLink>; Department of Psychiatry, Renmin Hospital of Wuhan University, Wuhan, China.<br /><searchLink fieldCode="AU" term="%22Kang+L%22">Kang L</searchLink>; Department of Psychiatry, Renmin Hospital of Wuhan University, Wuhan, China.<br /><searchLink fieldCode="AU" term="%22Chen+S%22">Chen S</searchLink>; Department of Psychiatry, Renmin Hospital of Wuhan University, Wuhan, China.<br /><searchLink fieldCode="AU" term="%22Liu+Z%22">Liu Z</searchLink>; Department of Psychiatry, Renmin Hospital of Wuhan University, Wuhan, China; Taikang Center for Life and Medical Sciences, Wuhan University, Wuhan, China; State Key Laboratory of Metabolism and Regulation in Complex Organisms, College of Life Sciences, Wuhan University, Wuhan, China. Electronic address: zcliu6@whu.edu.cn.
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  Data: <searchLink fieldCode="JN" term="%227906073%22">Journal of affective disorders</searchLink> [J Affect Disord] 2026 Jul 15; Vol. 405, pp. 121586. <i>Date of Electronic Publication: </i>2026 Mar 06.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Elsevier%2FNorth-Holland+Biomedical+Press%22">Elsevier/North-Holland Biomedical Press </searchLink><i>Country of Publication: </i>Netherlands <i>NLM ID: </i>7906073 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1573-2517 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2201650327%22">01650327 </searchLink><i>NLM ISO Abbreviation: </i>J Affect Disord <i>Subsets: </i>MEDLINE
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        Value: 10.1016/j.jad.2026.121586
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      – Code: eng
        Text: English
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        StartPage: 121586
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      – TitleFull: Multi-omics analysis reveals CXCL14+ inhibitory neuron dysfunction in major depressive disorder.
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              Text: 2026 Jul 15
              Type: published
              Y: 2026
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