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Assessing the presence of biasing and non-biasing unblinding in a randomized controlled trial of a home-use tDCS device: An exploratory analysis.

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Title: Assessing the presence of biasing and non-biasing unblinding in a randomized controlled trial of a home-use tDCS device: An exploratory analysis.
Authors: Hieronymus F; Institute of Neuroscience and Physiology, University of Gothenburg, Sweden; Department of Clinical Medicine, Aarhus university, Denmark. Electronic address: fredrik.hieronymus@neuro.gu.se., Huneke NTM; Clinical and Experimental Sciences, Faculty of Medicine, University of Southampton, UK; Hampshire and Isle of Wight Healthcare NHS Foundation Trust, Southampton, UK., Månsson D; Flow Neuroscience, Sweden., Rehn EM; Flow Neuroscience, Sweden., Hagsäter M; Institute of Neuroscience and Physiology, University of Gothenburg, Sweden., Woodham RD; Centre for Affective Disorders, Department of Psychological Medicine, Institute of Psychiatry, Psychology, and Neuroscience, King's College London, London, UK; University of East London, Department of Psychology, London, UK., Soares JC; Center of Excellence on Mood Disorders, Faillace Department of Psychiatry and Behavioral Sciences, McGovern Medical School, University of Texas Health Science Center at Houston, Houston, TX, USA., Young AH; Centre for Affective Disorders, Department of Psychological Medicine, Institute of Psychiatry, Psychology, and Neuroscience, King's College London, London, UK; National Institute for Health and Care Research (NIHR) Maudsley Biomedical Research Centre (BRC), King's College London, London, UK; South London and Maudsley NHS Foundation Trust, Bethlem Royal Hospital, Beckenham, UK; Division of Psychiatry, Department of Brain Sciences, Faculty of Medicine, Imperial College London, London, UK., Machado-Vieira R; Center of Excellence on Mood Disorders, Faillace Department of Psychiatry and Behavioral Sciences, McGovern Medical School, University of Texas Health Science Center at Houston, Houston, TX, USA., Selvaraj S; Center of Excellence on Mood Disorders, Faillace Department of Psychiatry and Behavioral Sciences, McGovern Medical School, University of Texas Health Science Center at Houston, Houston, TX, USA; Intra-Cellular Therapies Inc., USA., Fu C; Centre for Affective Disorders, Department of Psychological Medicine, Institute of Psychiatry, Psychology, and Neuroscience, King's College London, London, UK; Center of Excellence on Mood Disorders, Faillace Department of Psychiatry and Behavioral Sciences, McGovern Medical School, University of Texas Health Science Center at Houston, Houston, TX, USA; National Institute for Health and Care Research (NIHR) Maudsley Biomedical Research Centre (BRC), King's College London, London, UK.
Source: Journal of affective disorders [J Affect Disord] 2026 Jul 15; Vol. 405, pp. 121553. Date of Electronic Publication: 2026 Mar 06.
Publication Type: Journal Article; Randomized Controlled Trial
Journal Info: Publisher: Elsevier/North-Holland Biomedical Press Country of Publication: Netherlands NLM ID: 7906073 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1573-2517 (Electronic) Linking ISSN: 01650327 NLM ISO Abbreviation: J Affect Disord Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: <searchLink fieldCode="AU" term="%22Hieronymus+F%22">Hieronymus F</searchLink>; Institute of Neuroscience and Physiology, University of Gothenburg, Sweden; Department of Clinical Medicine, Aarhus university, Denmark. Electronic address: fredrik.hieronymus@neuro.gu.se.<br /><searchLink fieldCode="AU" term="%22Huneke+NTM%22">Huneke NTM</searchLink>; Clinical and Experimental Sciences, Faculty of Medicine, University of Southampton, UK; Hampshire and Isle of Wight Healthcare NHS Foundation Trust, Southampton, UK.<br /><searchLink fieldCode="AU" term="%22Månsson+D%22">Månsson D</searchLink>; Flow Neuroscience, Sweden.<br /><searchLink fieldCode="AU" term="%22Rehn+EM%22">Rehn EM</searchLink>; Flow Neuroscience, Sweden.<br /><searchLink fieldCode="AU" term="%22Hagsäter+M%22">Hagsäter M</searchLink>; Institute of Neuroscience and Physiology, University of Gothenburg, Sweden.<br /><searchLink fieldCode="AU" term="%22Woodham+RD%22">Woodham RD</searchLink>; Centre for Affective Disorders, Department of Psychological Medicine, Institute of Psychiatry, Psychology, and Neuroscience, King's College London, London, UK; University of East London, Department of Psychology, London, UK.<br /><searchLink fieldCode="AU" term="%22Soares+JC%22">Soares JC</searchLink>; Center of Excellence on Mood Disorders, Faillace Department of Psychiatry and Behavioral Sciences, McGovern Medical School, University of Texas Health Science Center at Houston, Houston, TX, USA.<br /><searchLink fieldCode="AU" term="%22Young+AH%22">Young AH</searchLink>; Centre for Affective Disorders, Department of Psychological Medicine, Institute of Psychiatry, Psychology, and Neuroscience, King's College London, London, UK; National Institute for Health and Care Research (NIHR) Maudsley Biomedical Research Centre (BRC), King's College London, London, UK; South London and Maudsley NHS Foundation Trust, Bethlem Royal Hospital, Beckenham, UK; Division of Psychiatry, Department of Brain Sciences, Faculty of Medicine, Imperial College London, London, UK.<br /><searchLink fieldCode="AU" term="%22Machado-Vieira+R%22">Machado-Vieira R</searchLink>; Center of Excellence on Mood Disorders, Faillace Department of Psychiatry and Behavioral Sciences, McGovern Medical School, University of Texas Health Science Center at Houston, Houston, TX, USA.<br /><searchLink fieldCode="AU" term="%22Selvaraj+S%22">Selvaraj S</searchLink>; Center of Excellence on Mood Disorders, Faillace Department of Psychiatry and Behavioral Sciences, McGovern Medical School, University of Texas Health Science Center at Houston, Houston, TX, USA; Intra-Cellular Therapies Inc., USA.<br /><searchLink fieldCode="AU" term="%22Fu+C%22">Fu C</searchLink>; Centre for Affective Disorders, Department of Psychological Medicine, Institute of Psychiatry, Psychology, and Neuroscience, King's College London, London, UK; Center of Excellence on Mood Disorders, Faillace Department of Psychiatry and Behavioral Sciences, McGovern Medical School, University of Texas Health Science Center at Houston, Houston, TX, USA; National Institute for Health and Care Research (NIHR) Maudsley Biomedical Research Centre (BRC), King's College London, London, UK.
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              Text: 2026 Jul 15
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