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PHIVE: A physics-informed variational encoder enables rapid spectral fitting of brain metabolite mapping at 7T.

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Title: PHIVE: A physics-informed variational encoder enables rapid spectral fitting of brain metabolite mapping at 7T.
Authors: Shamaei A; Electrical and Software Engineering, University of Calgary, Calgary, AB, Canada; Hotchkiss Brain Institute, University of Calgary, Calgary, AB, Canada., Buchali A; Massive Portraits, Vancouver, BC, Canada., Niess E; Department of Biomedical Imaging and Image-guided Therapy, Radiology and Nuclear Medicine, Medical University of Vienna, Vienna, Austria., Hingerl L; Department of Biomedical Imaging and Image-guided Therapy, Radiology and Nuclear Medicine, Medical University of Vienna, Vienna, Austria., Strasser B; Department of Biomedical Imaging and Image-guided Therapy, Radiology and Nuclear Medicine, Medical University of Vienna, Vienna, Austria., Osburg A; Department of Biomedical Imaging and Image-guided Therapy, Radiology and Nuclear Medicine, Medical University of Vienna, Vienna, Austria; Comprehensive Center for AI in Medicine (CAIM), Medical University of Vienna, Vienna, Austria., Eckstein K; Department of Biomedical Imaging and Image-guided Therapy, Radiology and Nuclear Medicine, Medical University of Vienna, Vienna, Austria; School of Electrical Engineering and Computer Science, The University of Queensland, St Lucia, Australia., Bogner W; Department of Biomedical Imaging and Image-guided Therapy, Radiology and Nuclear Medicine, Medical University of Vienna, Vienna, Austria; Christian Doppler Laboratory for MR Imaging Biomarker Development, Vienna, Austria; Comprehensive Center for AI in Medicine (CAIM), Medical University of Vienna, Vienna, Austria. Electronic address: wolfgang.bogner@meduniwien.ac.at., Motyka S; Department of Biomedical Imaging and Image-guided Therapy, Radiology and Nuclear Medicine, Medical University of Vienna, Vienna, Austria; Christian Doppler Laboratory for MR Imaging Biomarker Development, Vienna, Austria; Comprehensive Center for AI in Medicine (CAIM), Medical University of Vienna, Vienna, Austria.
Source: Medical image analysis [Med Image Anal] 2026 Jun; Vol. 111, pp. 104014. Date of Electronic Publication: 2026 Mar 03.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 9713490 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1361-8423 (Electronic) Linking ISSN: 13618415 NLM ISO Abbreviation: Med Image Anal Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: PHIVE: A physics-informed variational encoder enables rapid spectral fitting of brain metabolite mapping at 7T.
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  Data: <searchLink fieldCode="AU" term="%22Shamaei+A%22">Shamaei A</searchLink>; Electrical and Software Engineering, University of Calgary, Calgary, AB, Canada; Hotchkiss Brain Institute, University of Calgary, Calgary, AB, Canada.<br /><searchLink fieldCode="AU" term="%22Buchali+A%22">Buchali A</searchLink>; Massive Portraits, Vancouver, BC, Canada.<br /><searchLink fieldCode="AU" term="%22Niess+E%22">Niess E</searchLink>; Department of Biomedical Imaging and Image-guided Therapy, Radiology and Nuclear Medicine, Medical University of Vienna, Vienna, Austria.<br /><searchLink fieldCode="AU" term="%22Hingerl+L%22">Hingerl L</searchLink>; Department of Biomedical Imaging and Image-guided Therapy, Radiology and Nuclear Medicine, Medical University of Vienna, Vienna, Austria.<br /><searchLink fieldCode="AU" term="%22Strasser+B%22">Strasser B</searchLink>; Department of Biomedical Imaging and Image-guided Therapy, Radiology and Nuclear Medicine, Medical University of Vienna, Vienna, Austria.<br /><searchLink fieldCode="AU" term="%22Osburg+A%22">Osburg A</searchLink>; Department of Biomedical Imaging and Image-guided Therapy, Radiology and Nuclear Medicine, Medical University of Vienna, Vienna, Austria; Comprehensive Center for AI in Medicine (CAIM), Medical University of Vienna, Vienna, Austria.<br /><searchLink fieldCode="AU" term="%22Eckstein+K%22">Eckstein K</searchLink>; Department of Biomedical Imaging and Image-guided Therapy, Radiology and Nuclear Medicine, Medical University of Vienna, Vienna, Austria; School of Electrical Engineering and Computer Science, The University of Queensland, St Lucia, Australia.<br /><searchLink fieldCode="AU" term="%22Bogner+W%22">Bogner W</searchLink>; Department of Biomedical Imaging and Image-guided Therapy, Radiology and Nuclear Medicine, Medical University of Vienna, Vienna, Austria; Christian Doppler Laboratory for MR Imaging Biomarker Development, Vienna, Austria; Comprehensive Center for AI in Medicine (CAIM), Medical University of Vienna, Vienna, Austria. Electronic address: wolfgang.bogner@meduniwien.ac.at.<br /><searchLink fieldCode="AU" term="%22Motyka+S%22">Motyka S</searchLink>; Department of Biomedical Imaging and Image-guided Therapy, Radiology and Nuclear Medicine, Medical University of Vienna, Vienna, Austria; Christian Doppler Laboratory for MR Imaging Biomarker Development, Vienna, Austria; Comprehensive Center for AI in Medicine (CAIM), Medical University of Vienna, Vienna, Austria.
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  Data: <searchLink fieldCode="JN" term="%229713490%22">Medical image analysis</searchLink> [Med Image Anal] 2026 Jun; Vol. 111, pp. 104014. <i>Date of Electronic Publication: </i>2026 Mar 03.
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  Data: Journal Article; Research Support, Non-U.S. Gov't
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Elsevier%22">Elsevier </searchLink><i>Country of Publication: </i>Netherlands <i>NLM ID: </i>9713490 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1361-8423 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2213618415%22">13618415 </searchLink><i>NLM ISO Abbreviation: </i>Med Image Anal <i>Subsets: </i>MEDLINE
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        Value: 10.1016/j.media.2026.104014
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              Text: 2026 Jun
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