Elevated Polyreactive Immunoglobulin G in Immune-Mediated Liver Injuries With the Need for Immunosuppressive Therapy.

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Title: Elevated Polyreactive Immunoglobulin G in Immune-Mediated Liver Injuries With the Need for Immunosuppressive Therapy.
Authors: Kirchner T; Department of Gastroenterology, Hepatology, Infectious Diseases and Endocrinology, Hannover Medical School, Hannover, Germany.; European Reference Network on Hepatological Diseases (ERN RARE-LIVER), Hamburg, Germany., Dalekos GN; European Reference Network on Hepatological Diseases (ERN RARE-LIVER), Hamburg, Germany.; Department of Medicine and Research Laboratory of Internal Medicine, National Expertise Center of Greece in Autoimmune Liver Diseases, General University Hospital of Larissa, Larissa, Greece., Zachou K; European Reference Network on Hepatological Diseases (ERN RARE-LIVER), Hamburg, Germany.; Department of Medicine and Research Laboratory of Internal Medicine, National Expertise Center of Greece in Autoimmune Liver Diseases, General University Hospital of Larissa, Larissa, Greece., Robles-Díaz M; Unidad de Gestión Clínica de Aparato Digestivo, Instituto de Investigación Biomédica de Málaga-IBIMA, Plataforma BIONAND, CIBEREHD, Hospital Universitario Virgen de la Victoria, Universidad de Málaga, Málaga, Spain., Andrade RJ; Unidad de Gestión Clínica de Aparato Digestivo, Instituto de Investigación Biomédica de Málaga-IBIMA, Plataforma BIONAND, CIBEREHD, Hospital Universitario Virgen de la Victoria, Universidad de Málaga, Málaga, Spain., Sebode M; European Reference Network on Hepatological Diseases (ERN RARE-LIVER), Hamburg, Germany.; Department of Medicine, University Medical Centre Hamburg-Eppendorf, Hamburg, Germany., Lohse A; European Reference Network on Hepatological Diseases (ERN RARE-LIVER), Hamburg, Germany.; Department of Medicine, University Medical Centre Hamburg-Eppendorf, Hamburg, Germany., Janik MK; European Reference Network on Hepatological Diseases (ERN RARE-LIVER), Hamburg, Germany.; Department of Hepatology, Transplantology, Internal Medicine, Medical University of Warsaw, Warsaw, Poland., Milkiewicz P; European Reference Network on Hepatological Diseases (ERN RARE-LIVER), Hamburg, Germany.; Department of Hepatology, Transplantology, Internal Medicine, Medical University of Warsaw, Warsaw, Poland.; Translational Medicine Group, Pomeranian Medical University, Szczecin, Poland., Kolev M; Department of Visceral Surgery and Medicine, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland., Semmo N; Department of Visceral Surgery and Medicine, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland., Bruns T; European Reference Network on Hepatological Diseases (ERN RARE-LIVER), Hamburg, Germany.; Department of Medicine III, University Hospital RWTH Aachen, Aachen, Germany., Gevers TJ; European Reference Network on Hepatological Diseases (ERN RARE-LIVER), Hamburg, Germany.; Department of Gastroenterology and Hepatology, Maastricht University Medical Center, Maastricht, the Netherlands., Beretta-Piccoli BT; Epatocentro Ticino, Lugano, Switzerland., Wedemeyer H; Department of Gastroenterology, Hepatology, Infectious Diseases and Endocrinology, Hannover Medical School, Hannover, Germany.; European Reference Network on Hepatological Diseases (ERN RARE-LIVER), Hamburg, Germany., Jaeckel E; Department of Gastroenterology, Hepatology, Infectious Diseases and Endocrinology, Hannover Medical School, Hannover, Germany.; European Reference Network on Hepatological Diseases (ERN RARE-LIVER), Hamburg, Germany., Taubert R; Department of Gastroenterology, Hepatology, Infectious Diseases and Endocrinology, Hannover Medical School, Hannover, Germany.; European Reference Network on Hepatological Diseases (ERN RARE-LIVER), Hamburg, Germany., Engel B; Department of Gastroenterology, Hepatology, Infectious Diseases and Endocrinology, Hannover Medical School, Hannover, Germany.; European Reference Network on Hepatological Diseases (ERN RARE-LIVER), Hamburg, Germany.; PRACTIS & CORE100Pilot Clinician Scientist Programs, Dean's Office for Academic Career Development, Hannover Medical School, Hannover, Germany.
Corporate Authors: pIgG study group
Source: Liver international : official journal of the International Association for the Study of the Liver [Liver Int] 2026 Apr; Vol. 46 (4), pp. e70571.
Publication Type: Journal Article
Journal Info: Publisher: Wiley-Blackwell Country of Publication: United States NLM ID: 101160857 Publication Model: Print Cited Medium: Internet ISSN: 1478-3231 (Electronic) Linking ISSN: 14783223 NLM ISO Abbreviation: Liver Int Subsets: MEDLINE
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  Data: <searchLink fieldCode="AU" term="%22Kirchner+T%22">Kirchner T</searchLink>; Department of Gastroenterology, Hepatology, Infectious Diseases and Endocrinology, Hannover Medical School, Hannover, Germany.; European Reference Network on Hepatological Diseases (ERN RARE-LIVER), Hamburg, Germany.<br /><searchLink fieldCode="AU" term="%22Dalekos+GN%22">Dalekos GN</searchLink>; European Reference Network on Hepatological Diseases (ERN RARE-LIVER), Hamburg, Germany.; Department of Medicine and Research Laboratory of Internal Medicine, National Expertise Center of Greece in Autoimmune Liver Diseases, General University Hospital of Larissa, Larissa, Greece.<br /><searchLink fieldCode="AU" term="%22Zachou+K%22">Zachou K</searchLink>; European Reference Network on Hepatological Diseases (ERN RARE-LIVER), Hamburg, Germany.; Department of Medicine and Research Laboratory of Internal Medicine, National Expertise Center of Greece in Autoimmune Liver Diseases, General University Hospital of Larissa, Larissa, Greece.<br /><searchLink fieldCode="AU" term="%22Robles-Díaz+M%22">Robles-Díaz M</searchLink>; Unidad de Gestión Clínica de Aparato Digestivo, Instituto de Investigación Biomédica de Málaga-IBIMA, Plataforma BIONAND, CIBEREHD, Hospital Universitario Virgen de la Victoria, Universidad de Málaga, Málaga, Spain.<br /><searchLink fieldCode="AU" term="%22Andrade+RJ%22">Andrade RJ</searchLink>; Unidad de Gestión Clínica de Aparato Digestivo, Instituto de Investigación Biomédica de Málaga-IBIMA, Plataforma BIONAND, CIBEREHD, Hospital Universitario Virgen de la Victoria, Universidad de Málaga, Málaga, Spain.<br /><searchLink fieldCode="AU" term="%22Sebode+M%22">Sebode M</searchLink>; European Reference Network on Hepatological Diseases (ERN RARE-LIVER), Hamburg, Germany.; Department of Medicine, University Medical Centre Hamburg-Eppendorf, Hamburg, Germany.<br /><searchLink fieldCode="AU" term="%22Lohse+A%22">Lohse A</searchLink>; European Reference Network on Hepatological Diseases (ERN RARE-LIVER), Hamburg, Germany.; Department of Medicine, University Medical Centre Hamburg-Eppendorf, Hamburg, Germany.<br /><searchLink fieldCode="AU" term="%22Janik+MK%22">Janik MK</searchLink>; European Reference Network on Hepatological Diseases (ERN RARE-LIVER), Hamburg, Germany.; Department of Hepatology, Transplantology, Internal Medicine, Medical University of Warsaw, Warsaw, Poland.<br /><searchLink fieldCode="AU" term="%22Milkiewicz+P%22">Milkiewicz P</searchLink>; European Reference Network on Hepatological Diseases (ERN RARE-LIVER), Hamburg, Germany.; Department of Hepatology, Transplantology, Internal Medicine, Medical University of Warsaw, Warsaw, Poland.; Translational Medicine Group, Pomeranian Medical University, Szczecin, Poland.<br /><searchLink fieldCode="AU" term="%22Kolev+M%22">Kolev M</searchLink>; Department of Visceral Surgery and Medicine, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland.<br /><searchLink fieldCode="AU" term="%22Semmo+N%22">Semmo N</searchLink>; Department of Visceral Surgery and Medicine, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland.<br /><searchLink fieldCode="AU" term="%22Bruns+T%22">Bruns T</searchLink>; European Reference Network on Hepatological Diseases (ERN RARE-LIVER), Hamburg, Germany.; Department of Medicine III, University Hospital RWTH Aachen, Aachen, Germany.<br /><searchLink fieldCode="AU" term="%22Gevers+TJ%22">Gevers TJ</searchLink>; European Reference Network on Hepatological Diseases (ERN RARE-LIVER), Hamburg, Germany.; Department of Gastroenterology and Hepatology, Maastricht University Medical Center, Maastricht, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Beretta-Piccoli+BT%22">Beretta-Piccoli BT</searchLink>; Epatocentro Ticino, Lugano, Switzerland.<br /><searchLink fieldCode="AU" term="%22Wedemeyer+H%22">Wedemeyer H</searchLink>; Department of Gastroenterology, Hepatology, Infectious Diseases and Endocrinology, Hannover Medical School, Hannover, Germany.; European Reference Network on Hepatological Diseases (ERN RARE-LIVER), Hamburg, Germany.<br /><searchLink fieldCode="AU" term="%22Jaeckel+E%22">Jaeckel E</searchLink>; Department of Gastroenterology, Hepatology, Infectious Diseases and Endocrinology, Hannover Medical School, Hannover, Germany.; European Reference Network on Hepatological Diseases (ERN RARE-LIVER), Hamburg, Germany.<br /><searchLink fieldCode="AU" term="%22Taubert+R%22">Taubert R</searchLink>; Department of Gastroenterology, Hepatology, Infectious Diseases and Endocrinology, Hannover Medical School, Hannover, Germany.; European Reference Network on Hepatological Diseases (ERN RARE-LIVER), Hamburg, Germany.<br /><searchLink fieldCode="AU" term="%22Engel+B%22">Engel B</searchLink>; Department of Gastroenterology, Hepatology, Infectious Diseases and Endocrinology, Hannover Medical School, Hannover, Germany.; European Reference Network on Hepatological Diseases (ERN RARE-LIVER), Hamburg, Germany.; PRACTIS & CORE100Pilot Clinician Scientist Programs, Dean's Office for Academic Career Development, Hannover Medical School, Hannover, Germany.
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