CAIX-targeted α therapy directed against hypoxic tumor cells in combination with immune checkpoint inhibitors in a syngeneic mouse tumor model.

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Title: CAIX-targeted α therapy directed against hypoxic tumor cells in combination with immune checkpoint inhibitors in a syngeneic mouse tumor model.
Authors: Wenker STM; Department of Medical Imaging: Nuclear Medicine, Radboudumc, Geert Grooteplein Zuid 10, 6525GA Nijmegen, The Netherlands.; Department of Radiation Oncology: Radiotherapy & Oncoimmunology laboratory, Radboudumc, Geert Grooteplein Zuid 10, 6525GA Nijmegen, The Netherlands., Konijnenberg MW; Department of Medical Imaging: Nuclear Medicine, Radboudumc, Geert Grooteplein Zuid 10, 6525GA Nijmegen, The Netherlands.; Department of Radiology & Nuclear Medicine, Erasmus MC, Dr. Molewaterplein 40, 3015GD Rotterdam, The Netherlands., Lobeek D; Department of Medical Imaging: Nuclear Medicine, Radboudumc, Geert Grooteplein Zuid 10, 6525GA Nijmegen, The Netherlands.; Department of Radiology and Nuclear Medicine, Catharina Hospital, Michelangelolaan 2, 5623EJ Eindhoven, The Netherlands., Tamborino G; Department of Radiology & Nuclear Medicine, Erasmus MC, Dr. Molewaterplein 40, 3015GD Rotterdam, The Netherlands., Molkenboer-Kuenen JDM; Department of Medical Imaging: Nuclear Medicine, Radboudumc, Geert Grooteplein Zuid 10, 6525GA Nijmegen, The Netherlands., Franssen GM; Department of Medical Imaging: Nuclear Medicine, Radboudumc, Geert Grooteplein Zuid 10, 6525GA Nijmegen, The Netherlands., Boreel DF; Department of Medical Imaging: Nuclear Medicine, Radboudumc, Geert Grooteplein Zuid 10, 6525GA Nijmegen, The Netherlands.; Department of Radiation Oncology: Radiotherapy & Oncoimmunology laboratory, Radboudumc, Geert Grooteplein Zuid 10, 6525GA Nijmegen, The Netherlands., Kleinendorst SC; Department of Medical Imaging: Nuclear Medicine, Radboudumc, Geert Grooteplein Zuid 10, 6525GA Nijmegen, The Netherlands., Peters H; Department of Radiation Oncology: Radiotherapy & Oncoimmunology laboratory, Radboudumc, Geert Grooteplein Zuid 10, 6525GA Nijmegen, The Netherlands., Bussink J; Department of Radiation Oncology: Radiotherapy & Oncoimmunology laboratory, Radboudumc, Geert Grooteplein Zuid 10, 6525GA Nijmegen, The Netherlands., van Lith SAM; Department of Medical Imaging: Nuclear Medicine, Radboudumc, Geert Grooteplein Zuid 10, 6525GA Nijmegen, The Netherlands., Heskamp S; Department of Medical Imaging: Nuclear Medicine, Radboudumc, Geert Grooteplein Zuid 10, 6525GA Nijmegen, The Netherlands.
Source: Theranostics [Theranostics] 2026 Feb 11; Vol. 16 (9), pp. 4508-4520. Date of Electronic Publication: 2026 Feb 11 (Print Publication: 2026).
Publication Type: Journal Article
Journal Info: Publisher: Ivyspring International Publisher Country of Publication: Australia NLM ID: 101552395 Publication Model: eCollection Cited Medium: Internet ISSN: 1838-7640 (Electronic) Linking ISSN: 18387640 NLM ISO Abbreviation: Theranostics Subsets: MEDLINE
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  Data: CAIX-targeted α therapy directed against hypoxic tumor cells in combination with immune checkpoint inhibitors in a syngeneic mouse tumor model.
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  Data: <searchLink fieldCode="AU" term="%22Wenker+STM%22">Wenker STM</searchLink>; Department of Medical Imaging: Nuclear Medicine, Radboudumc, Geert Grooteplein Zuid 10, 6525GA Nijmegen, The Netherlands.; Department of Radiation Oncology: Radiotherapy & Oncoimmunology laboratory, Radboudumc, Geert Grooteplein Zuid 10, 6525GA Nijmegen, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Konijnenberg+MW%22">Konijnenberg MW</searchLink>; Department of Medical Imaging: Nuclear Medicine, Radboudumc, Geert Grooteplein Zuid 10, 6525GA Nijmegen, The Netherlands.; Department of Radiology & Nuclear Medicine, Erasmus MC, Dr. Molewaterplein 40, 3015GD Rotterdam, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Lobeek+D%22">Lobeek D</searchLink>; Department of Medical Imaging: Nuclear Medicine, Radboudumc, Geert Grooteplein Zuid 10, 6525GA Nijmegen, The Netherlands.; Department of Radiology and Nuclear Medicine, Catharina Hospital, Michelangelolaan 2, 5623EJ Eindhoven, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Tamborino+G%22">Tamborino G</searchLink>; Department of Radiology & Nuclear Medicine, Erasmus MC, Dr. Molewaterplein 40, 3015GD Rotterdam, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Molkenboer-Kuenen+JDM%22">Molkenboer-Kuenen JDM</searchLink>; Department of Medical Imaging: Nuclear Medicine, Radboudumc, Geert Grooteplein Zuid 10, 6525GA Nijmegen, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Franssen+GM%22">Franssen GM</searchLink>; Department of Medical Imaging: Nuclear Medicine, Radboudumc, Geert Grooteplein Zuid 10, 6525GA Nijmegen, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Boreel+DF%22">Boreel DF</searchLink>; Department of Medical Imaging: Nuclear Medicine, Radboudumc, Geert Grooteplein Zuid 10, 6525GA Nijmegen, The Netherlands.; Department of Radiation Oncology: Radiotherapy & Oncoimmunology laboratory, Radboudumc, Geert Grooteplein Zuid 10, 6525GA Nijmegen, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Kleinendorst+SC%22">Kleinendorst SC</searchLink>; Department of Medical Imaging: Nuclear Medicine, Radboudumc, Geert Grooteplein Zuid 10, 6525GA Nijmegen, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Peters+H%22">Peters H</searchLink>; Department of Radiation Oncology: Radiotherapy & Oncoimmunology laboratory, Radboudumc, Geert Grooteplein Zuid 10, 6525GA Nijmegen, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Bussink+J%22">Bussink J</searchLink>; Department of Radiation Oncology: Radiotherapy & Oncoimmunology laboratory, Radboudumc, Geert Grooteplein Zuid 10, 6525GA Nijmegen, The Netherlands.<br /><searchLink fieldCode="AU" term="%22van+Lith+SAM%22">van Lith SAM</searchLink>; Department of Medical Imaging: Nuclear Medicine, Radboudumc, Geert Grooteplein Zuid 10, 6525GA Nijmegen, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Heskamp+S%22">Heskamp S</searchLink>; Department of Medical Imaging: Nuclear Medicine, Radboudumc, Geert Grooteplein Zuid 10, 6525GA Nijmegen, The Netherlands.
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  Data: <searchLink fieldCode="JN" term="%22101552395%22">Theranostics</searchLink> [Theranostics] 2026 Feb 11; Vol. 16 (9), pp. 4508-4520. <i>Date of Electronic Publication: </i>2026 Feb 11 (<i>Print Publication: </i>2026).
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Ivyspring+International+Publisher%22">Ivyspring International Publisher </searchLink><i>Country of Publication: </i>Australia <i>NLM ID: </i>101552395 <i>Publication Model: </i>eCollection <i>Cited Medium: </i>Internet <i>ISSN: </i>1838-7640 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2218387640%22">18387640 </searchLink><i>NLM ISO Abbreviation: </i>Theranostics <i>Subsets: </i>MEDLINE
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              Text: 2026 Feb 11
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