Trans-Omics Integration Reveals That the Kidney Contributes to Systemic Aging via Sexually Dimorphic Accumulation of Glycosphingolipids.

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Title: Trans-Omics Integration Reveals That the Kidney Contributes to Systemic Aging via Sexually Dimorphic Accumulation of Glycosphingolipids.
Authors: Ni Z; State Key Laboratory of Molecular Developmental Biology, Institute of Genetics and Developmental Biology, Chinese Academy of Sciences Beijing China.; Beijing Life Science Academy Beijing China.; University of Chinese Academy of Sciences Beijing China., Cao C; State Key Laboratory of Molecular Developmental Biology, Institute of Genetics and Developmental Biology, Chinese Academy of Sciences Beijing China.; University of Chinese Academy of Sciences Beijing China., Tian Y; State Key Laboratory of Molecular Developmental Biology, Institute of Genetics and Developmental Biology, Chinese Academy of Sciences Beijing China.; University of Chinese Academy of Sciences Beijing China., Mu J; State Key Laboratory of Molecular Developmental Biology, Institute of Genetics and Developmental Biology, Chinese Academy of Sciences Beijing China.; University of Chinese Academy of Sciences Beijing China., Tian H; Guangzhou National Laboratory Guangzhou China., Wang Z; Guangzhou National Laboratory Guangzhou China., Zhang S; State Key Laboratory of Molecular Developmental Biology, Institute of Genetics and Developmental Biology, Chinese Academy of Sciences Beijing China., Cao M; State Key Laboratory of Molecular Developmental Biology, Institute of Genetics and Developmental Biology, Chinese Academy of Sciences Beijing China., Yang Y; Guangzhou National Laboratory Guangzhou China., Lim WLF; Jiangsu Provincial Key Laboratory of Molecular Targets and Intervention for Metabolic Diseases LipidALL Technologies Company Limited Changzhou China., Cui J; Jiangsu Provincial Key Laboratory of Molecular Targets and Intervention for Metabolic Diseases LipidALL Technologies Company Limited Changzhou China., Sun H; State Key Laboratory of Molecular Developmental Biology, Institute of Genetics and Developmental Biology, Chinese Academy of Sciences Beijing China.; University of Chinese Academy of Sciences Beijing China., Miao H; State Key Laboratory of Molecular Developmental Biology, Institute of Genetics and Developmental Biology, Chinese Academy of Sciences Beijing China.; University of Chinese Academy of Sciences Beijing China., Wang Y; Beijing Anzhen Hospital Capital Medical University Beijing China., Du J; Beijing Anzhen Hospital Capital Medical University Beijing China., Kwok T; Department of Medicine and Therapeutics The Chinese University of Hong Kong, Prince of Wales Hospital Shatin China., Chen H; Beijing Life Science Academy Beijing China., Lam SM; Jiangsu Provincial Key Laboratory of Molecular Targets and Intervention for Metabolic Diseases LipidALL Technologies Company Limited Changzhou China.; Guangzhou Institute of Cancer Research, the Affiliated Cancer Hospital Guangzhou Medical University Guangzhou China., Shui G; State Key Laboratory of Molecular Developmental Biology, Institute of Genetics and Developmental Biology, Chinese Academy of Sciences Beijing China.; University of Chinese Academy of Sciences Beijing China.; Guangzhou National Laboratory Guangzhou China.
Source: MedComm [MedComm (2020)] 2026 Mar 07; Vol. 7 (3), pp. e70669. Date of Electronic Publication: 2026 Mar 07 (Print Publication: 2026).
Publication Type: Journal Article
Journal Info: Publisher: John Wiley & Sons, Inc Country of Publication: China NLM ID: 101769925 Publication Model: eCollection Cited Medium: Internet ISSN: 2688-2663 (Electronic) Linking ISSN: 26882663 NLM ISO Abbreviation: MedComm (2020) Subsets: PubMed not MEDLINE
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  Data: Trans-Omics Integration Reveals That the Kidney Contributes to Systemic Aging via Sexually Dimorphic Accumulation of Glycosphingolipids.
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  Data: <searchLink fieldCode="AU" term="%22Ni+Z%22">Ni Z</searchLink>; State Key Laboratory of Molecular Developmental Biology, Institute of Genetics and Developmental Biology, Chinese Academy of Sciences Beijing China.; Beijing Life Science Academy Beijing China.; University of Chinese Academy of Sciences Beijing China.<br /><searchLink fieldCode="AU" term="%22Cao+C%22">Cao C</searchLink>; State Key Laboratory of Molecular Developmental Biology, Institute of Genetics and Developmental Biology, Chinese Academy of Sciences Beijing China.; University of Chinese Academy of Sciences Beijing China.<br /><searchLink fieldCode="AU" term="%22Tian+Y%22">Tian Y</searchLink>; State Key Laboratory of Molecular Developmental Biology, Institute of Genetics and Developmental Biology, Chinese Academy of Sciences Beijing China.; University of Chinese Academy of Sciences Beijing China.<br /><searchLink fieldCode="AU" term="%22Mu+J%22">Mu J</searchLink>; State Key Laboratory of Molecular Developmental Biology, Institute of Genetics and Developmental Biology, Chinese Academy of Sciences Beijing China.; University of Chinese Academy of Sciences Beijing China.<br /><searchLink fieldCode="AU" term="%22Tian+H%22">Tian H</searchLink>; Guangzhou National Laboratory Guangzhou China.<br /><searchLink fieldCode="AU" term="%22Wang+Z%22">Wang Z</searchLink>; Guangzhou National Laboratory Guangzhou China.<br /><searchLink fieldCode="AU" term="%22Zhang+S%22">Zhang S</searchLink>; State Key Laboratory of Molecular Developmental Biology, Institute of Genetics and Developmental Biology, Chinese Academy of Sciences Beijing China.<br /><searchLink fieldCode="AU" term="%22Cao+M%22">Cao M</searchLink>; State Key Laboratory of Molecular Developmental Biology, Institute of Genetics and Developmental Biology, Chinese Academy of Sciences Beijing China.<br /><searchLink fieldCode="AU" term="%22Yang+Y%22">Yang Y</searchLink>; Guangzhou National Laboratory Guangzhou China.<br /><searchLink fieldCode="AU" term="%22Lim+WLF%22">Lim WLF</searchLink>; Jiangsu Provincial Key Laboratory of Molecular Targets and Intervention for Metabolic Diseases LipidALL Technologies Company Limited Changzhou China.<br /><searchLink fieldCode="AU" term="%22Cui+J%22">Cui J</searchLink>; Jiangsu Provincial Key Laboratory of Molecular Targets and Intervention for Metabolic Diseases LipidALL Technologies Company Limited Changzhou China.<br /><searchLink fieldCode="AU" term="%22Sun+H%22">Sun H</searchLink>; State Key Laboratory of Molecular Developmental Biology, Institute of Genetics and Developmental Biology, Chinese Academy of Sciences Beijing China.; University of Chinese Academy of Sciences Beijing China.<br /><searchLink fieldCode="AU" term="%22Miao+H%22">Miao H</searchLink>; State Key Laboratory of Molecular Developmental Biology, Institute of Genetics and Developmental Biology, Chinese Academy of Sciences Beijing China.; University of Chinese Academy of Sciences Beijing China.<br /><searchLink fieldCode="AU" term="%22Wang+Y%22">Wang Y</searchLink>; Beijing Anzhen Hospital Capital Medical University Beijing China.<br /><searchLink fieldCode="AU" term="%22Du+J%22">Du J</searchLink>; Beijing Anzhen Hospital Capital Medical University Beijing China.<br /><searchLink fieldCode="AU" term="%22Kwok+T%22">Kwok T</searchLink>; Department of Medicine and Therapeutics The Chinese University of Hong Kong, Prince of Wales Hospital Shatin China.<br /><searchLink fieldCode="AU" term="%22Chen+H%22">Chen H</searchLink>; Beijing Life Science Academy Beijing China.<br /><searchLink fieldCode="AU" term="%22Lam+SM%22">Lam SM</searchLink>; Jiangsu Provincial Key Laboratory of Molecular Targets and Intervention for Metabolic Diseases LipidALL Technologies Company Limited Changzhou China.; Guangzhou Institute of Cancer Research, the Affiliated Cancer Hospital Guangzhou Medical University Guangzhou China.<br /><searchLink fieldCode="AU" term="%22Shui+G%22">Shui G</searchLink>; State Key Laboratory of Molecular Developmental Biology, Institute of Genetics and Developmental Biology, Chinese Academy of Sciences Beijing China.; University of Chinese Academy of Sciences Beijing China.; Guangzhou National Laboratory Guangzhou China.
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