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Population Pharmacokinetics and Cerebrospinal Fluid Penetration of Intravenous Vancomycin in Intracranial Hemorrhage Patients with External Ventricular Drains: Implications for Dosing and Therapeutic Drug Monitoring.

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Title: Population Pharmacokinetics and Cerebrospinal Fluid Penetration of Intravenous Vancomycin in Intracranial Hemorrhage Patients with External Ventricular Drains: Implications for Dosing and Therapeutic Drug Monitoring.
Authors: Tseng YJ; Department of Pharmacy, National Taiwan University Hospital, Taipei, Taiwan.; School of Pharmacy, College of Medicine, National Taiwan University, Taipei, Taiwan., Juan L; School of Pharmacy, College of Medicine, National Taiwan University, Taipei, Taiwan., Wu CC; Department of Pharmacy, National Taiwan University Hospital, Taipei, Taiwan.; School of Pharmacy, College of Medicine, National Taiwan University, Taipei, Taiwan., Lan YX; Department of Medical Research, National Taiwan University, Taipei, Taiwan., Chen GY; Forensic and Clinical Toxicology Center, National Taiwan University Hospital, Taipei, Taiwan.; Department and Graduate Institute of Forensic Medicine, College of Medicine, National Taiwan University, Taipei, Taiwan., Huang AP; Division of Neurosurgery, Department of Surgery, National Taiwan University Hospital, Taipei, Taiwan., Chen KW; Division of Neurosurgery, Department of Surgery, National Taiwan University Hospital, Taipei, Taiwan., Wang KC; Division of Neurosurgery, Department of Surgery, National Taiwan University Hospital, Taipei, Taiwan., Luh HT; Medical Department, International SOS Company Limited, Taipei, Taiwan.; Division of Neurosurgery, Department of Surgery, National Taiwan University Hospital Hsin-Chu Branch, Hsin-Chu, Taiwan., Lin SW; School of Pharmacy, College of Medicine, National Taiwan University, Taipei, Taiwan.; Graduate Institute of Clinical Pharmacy, College of Medicine, National Taiwan University, Taipei, Taiwan.; Department of Pharmacy, National Taiwan University Cancer Center, Taipei, Taiwan.
Source: Drug design, development and therapy [Drug Des Devel Ther] 2026 Mar 02; Vol. 20, pp. 574548. Date of Electronic Publication: 2026 Mar 02 (Print Publication: 2026).
Publication Type: Journal Article; Observational Study
Journal Info: Publisher: Dove Press Limited Country of Publication: New Zealand NLM ID: 101475745 Publication Model: eCollection Cited Medium: Internet ISSN: 1177-8881 (Electronic) Linking ISSN: 11778881 NLM ISO Abbreviation: Drug Des Devel Ther Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Population Pharmacokinetics and Cerebrospinal Fluid Penetration of Intravenous Vancomycin in Intracranial Hemorrhage Patients with External Ventricular Drains: Implications for Dosing and Therapeutic Drug Monitoring.
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  Data: <searchLink fieldCode="AU" term="%22Tseng+YJ%22">Tseng YJ</searchLink>; Department of Pharmacy, National Taiwan University Hospital, Taipei, Taiwan.; School of Pharmacy, College of Medicine, National Taiwan University, Taipei, Taiwan.<br /><searchLink fieldCode="AU" term="%22Juan+L%22">Juan L</searchLink>; School of Pharmacy, College of Medicine, National Taiwan University, Taipei, Taiwan.<br /><searchLink fieldCode="AU" term="%22Wu+CC%22">Wu CC</searchLink>; Department of Pharmacy, National Taiwan University Hospital, Taipei, Taiwan.; School of Pharmacy, College of Medicine, National Taiwan University, Taipei, Taiwan.<br /><searchLink fieldCode="AU" term="%22Lan+YX%22">Lan YX</searchLink>; Department of Medical Research, National Taiwan University, Taipei, Taiwan.<br /><searchLink fieldCode="AU" term="%22Chen+GY%22">Chen GY</searchLink>; Forensic and Clinical Toxicology Center, National Taiwan University Hospital, Taipei, Taiwan.; Department and Graduate Institute of Forensic Medicine, College of Medicine, National Taiwan University, Taipei, Taiwan.<br /><searchLink fieldCode="AU" term="%22Huang+AP%22">Huang AP</searchLink>; Division of Neurosurgery, Department of Surgery, National Taiwan University Hospital, Taipei, Taiwan.<br /><searchLink fieldCode="AU" term="%22Chen+KW%22">Chen KW</searchLink>; Division of Neurosurgery, Department of Surgery, National Taiwan University Hospital, Taipei, Taiwan.<br /><searchLink fieldCode="AU" term="%22Wang+KC%22">Wang KC</searchLink>; Division of Neurosurgery, Department of Surgery, National Taiwan University Hospital, Taipei, Taiwan.<br /><searchLink fieldCode="AU" term="%22Luh+HT%22">Luh HT</searchLink>; Medical Department, International SOS Company Limited, Taipei, Taiwan.; Division of Neurosurgery, Department of Surgery, National Taiwan University Hospital Hsin-Chu Branch, Hsin-Chu, Taiwan.<br /><searchLink fieldCode="AU" term="%22Lin+SW%22">Lin SW</searchLink>; School of Pharmacy, College of Medicine, National Taiwan University, Taipei, Taiwan.; Graduate Institute of Clinical Pharmacy, College of Medicine, National Taiwan University, Taipei, Taiwan.; Department of Pharmacy, National Taiwan University Cancer Center, Taipei, Taiwan.
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  Data: <searchLink fieldCode="JN" term="%22101475745%22">Drug design, development and therapy</searchLink> [Drug Des Devel Ther] 2026 Mar 02; Vol. 20, pp. 574548. <i>Date of Electronic Publication: </i>2026 Mar 02 (<i>Print Publication: </i>2026).
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Dove+Press+Limited%22">Dove Press Limited </searchLink><i>Country of Publication: </i>New Zealand <i>NLM ID: </i>101475745 <i>Publication Model: </i>eCollection <i>Cited Medium: </i>Internet <i>ISSN: </i>1177-8881 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2211778881%22">11778881 </searchLink><i>NLM ISO Abbreviation: </i>Drug Des Devel Ther <i>Subsets: </i>MEDLINE
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              Text: 2026 Mar 02
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