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Differences in Disease Trajectory, Comorbidities, and Mortality in Sarcomeric and Nonsarcomeric Hypertrophic Cardiomyopathy.

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Title: Differences in Disease Trajectory, Comorbidities, and Mortality in Sarcomeric and Nonsarcomeric Hypertrophic Cardiomyopathy.
Authors: Vissing CR; Department of Cardiology, Rigshospitalet, Copenhagen University Hospital, Denmark (C.R.V., A.A.R., H.B.).; Department of Cardiology, Hvidovre Hospital, Copenhagen University Hospital, Denmark (C.R.V.)., Axelsson Raja A; Department of Cardiology, Rigshospitalet, Copenhagen University Hospital, Denmark (C.R.V., A.A.R., H.B.)., Helms AS; Department of Internal Medicine, Division of Cardiovascular Medicine, University of Michigan, Ann Arbor (A.S.H., S.S.)., Saberi S; Department of Internal Medicine, Division of Cardiovascular Medicine, University of Michigan, Ann Arbor (A.S.H., S.S.)., Owens AT; Division of Cardiology, University of Pennsylvania, PA (A.T.O., S.M.D.)., Rossano JW, Abrams DJ; Center for Cardiovascular Genetics, Department of Cardiology, Boston Children's Hospital & Harvard Medical School, Boston, MA (D.J.A)., Ingles J; Genomics and Inherited Disease Program, Garvan Institute of Medical Research and University of New South Wales, Sydney, Australia (J.I.)., Gray B; Faculty of Medicine and Health, The University of Sydney, Australia, Department of Cardiology, Royal Prince Alfred Hospital, Sydney, Australia (B.G)., Lampert R; Department of Medicine, Section of Cardiovascular Medicine, Yale School of Medicine, New Haven, CT (R.L, J.C.S)., Stendahl JC; Department of Medicine, Section of Cardiovascular Medicine, Yale School of Medicine, New Haven, CT (R.L, J.C.S)., Lakdawala NK; Department of Medicine, Brigham and Women's Hospital, Boston, MA (B.L.C, N.K.L., C.Y.H.)., Ware JS; Royal Brompton & Harefield Hospitals, Guy's and St. Thomas' NHS Foundation Trust, London, United Kingdom (J.S.W.)., Parikh VN; Center for Inherited Cardiovascular Disease, Division of Cardiovascular Medicine, Stanford University School of Medicine, Stanford, CA (V.N.P.)., Michels M; Cardiovascular Institute, Thoraxcenter, Department of Cardiology, Thoraxcenter, Erasmus Medical Center Rotterdam, the Netherlands (M.M.)., Crotti L; Department of Medicine and Surgery, University of Milano-Bicocca, Milan, Italy (L.C.).; IRCCS, Istituto Auxologico Italiano, Department of Cardiology, San Luca Hospital, Cardiomyopathy Unit, Milan, Italy (L.C.)., Ryan TD; Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, OH; Division of Cardiology, The Heart Institute, Cincinnati Children's Hospital Medical Center, Cincinnati, OH (E.M., T.D.R.)., Olivotto I; Meyer Children's Hospital IRCCS, Florence, Italy (I.O.)., Day SM; Division of Cardiology, University of Pennsylvania, PA (A.T.O., S.M.D.)., Bundgaard H; Department of Cardiology, Rigshospitalet, Copenhagen University Hospital, Denmark (C.R.V., A.A.R., H.B.)., Claggett BL; Department of Medicine, Brigham and Women's Hospital, Boston, MA (B.L.C, N.K.L., C.Y.H.)., Ho CY; Department of Medicine, Brigham and Women's Hospital, Boston, MA (B.L.C, N.K.L., C.Y.H.).
Source: Circulation [Circulation] 2026 Apr 14; Vol. 153 (15), pp. 1104-1116. Date of Electronic Publication: 2026 Mar 09.
Publication Type: Journal Article; Multicenter Study
Journal Info: Publisher: Lippincott Williams & Wilkins Country of Publication: United States NLM ID: 0147763 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1524-4539 (Electronic) Linking ISSN: 00097322 NLM ISO Abbreviation: Circulation Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Differences in Disease Trajectory, Comorbidities, and Mortality in Sarcomeric and Nonsarcomeric Hypertrophic Cardiomyopathy.
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  Data: <searchLink fieldCode="AU" term="%22Vissing+CR%22">Vissing CR</searchLink>; Department of Cardiology, Rigshospitalet, Copenhagen University Hospital, Denmark (C.R.V., A.A.R., H.B.).; Department of Cardiology, Hvidovre Hospital, Copenhagen University Hospital, Denmark (C.R.V.).<br /><searchLink fieldCode="AU" term="%22Axelsson+Raja+A%22">Axelsson Raja A</searchLink>; Department of Cardiology, Rigshospitalet, Copenhagen University Hospital, Denmark (C.R.V., A.A.R., H.B.).<br /><searchLink fieldCode="AU" term="%22Helms+AS%22">Helms AS</searchLink>; Department of Internal Medicine, Division of Cardiovascular Medicine, University of Michigan, Ann Arbor (A.S.H., S.S.).<br /><searchLink fieldCode="AU" term="%22Saberi+S%22">Saberi S</searchLink>; Department of Internal Medicine, Division of Cardiovascular Medicine, University of Michigan, Ann Arbor (A.S.H., S.S.).<br /><searchLink fieldCode="AU" term="%22Owens+AT%22">Owens AT</searchLink>; Division of Cardiology, University of Pennsylvania, PA (A.T.O., S.M.D.).<br /><searchLink fieldCode="AU" term="%22Rossano+JW%22">Rossano JW</searchLink><br /><searchLink fieldCode="AU" term="%22Abrams+DJ%22">Abrams DJ</searchLink>; Center for Cardiovascular Genetics, Department of Cardiology, Boston Children's Hospital & Harvard Medical School, Boston, MA (D.J.A).<br /><searchLink fieldCode="AU" term="%22Ingles+J%22">Ingles J</searchLink>; Genomics and Inherited Disease Program, Garvan Institute of Medical Research and University of New South Wales, Sydney, Australia (J.I.).<br /><searchLink fieldCode="AU" term="%22Gray+B%22">Gray B</searchLink>; Faculty of Medicine and Health, The University of Sydney, Australia, Department of Cardiology, Royal Prince Alfred Hospital, Sydney, Australia (B.G).<br /><searchLink fieldCode="AU" term="%22Lampert+R%22">Lampert R</searchLink>; Department of Medicine, Section of Cardiovascular Medicine, Yale School of Medicine, New Haven, CT (R.L, J.C.S).<br /><searchLink fieldCode="AU" term="%22Stendahl+JC%22">Stendahl JC</searchLink>; Department of Medicine, Section of Cardiovascular Medicine, Yale School of Medicine, New Haven, CT (R.L, J.C.S).<br /><searchLink fieldCode="AU" term="%22Lakdawala+NK%22">Lakdawala NK</searchLink>; Department of Medicine, Brigham and Women's Hospital, Boston, MA (B.L.C, N.K.L., C.Y.H.).<br /><searchLink fieldCode="AU" term="%22Ware+JS%22">Ware JS</searchLink>; Royal Brompton & Harefield Hospitals, Guy's and St. Thomas' NHS Foundation Trust, London, United Kingdom (J.S.W.).<br /><searchLink fieldCode="AU" term="%22Parikh+VN%22">Parikh VN</searchLink>; Center for Inherited Cardiovascular Disease, Division of Cardiovascular Medicine, Stanford University School of Medicine, Stanford, CA (V.N.P.).<br /><searchLink fieldCode="AU" term="%22Michels+M%22">Michels M</searchLink>; Cardiovascular Institute, Thoraxcenter, Department of Cardiology, Thoraxcenter, Erasmus Medical Center Rotterdam, the Netherlands (M.M.).<br /><searchLink fieldCode="AU" term="%22Crotti+L%22">Crotti L</searchLink>; Department of Medicine and Surgery, University of Milano-Bicocca, Milan, Italy (L.C.).; IRCCS, Istituto Auxologico Italiano, Department of Cardiology, San Luca Hospital, Cardiomyopathy Unit, Milan, Italy (L.C.).<br /><searchLink fieldCode="AU" term="%22Ryan+TD%22">Ryan TD</searchLink>; Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, OH; Division of Cardiology, The Heart Institute, Cincinnati Children's Hospital Medical Center, Cincinnati, OH (E.M., T.D.R.).<br /><searchLink fieldCode="AU" term="%22Olivotto+I%22">Olivotto I</searchLink>; Meyer Children's Hospital IRCCS, Florence, Italy (I.O.).<br /><searchLink fieldCode="AU" term="%22Day+SM%22">Day SM</searchLink>; Division of Cardiology, University of Pennsylvania, PA (A.T.O., S.M.D.).<br /><searchLink fieldCode="AU" term="%22Bundgaard+H%22">Bundgaard H</searchLink>; Department of Cardiology, Rigshospitalet, Copenhagen University Hospital, Denmark (C.R.V., A.A.R., H.B.).<br /><searchLink fieldCode="AU" term="%22Claggett+BL%22">Claggett BL</searchLink>; Department of Medicine, Brigham and Women's Hospital, Boston, MA (B.L.C, N.K.L., C.Y.H.).<br /><searchLink fieldCode="AU" term="%22Ho+CY%22">Ho CY</searchLink>; Department of Medicine, Brigham and Women's Hospital, Boston, MA (B.L.C, N.K.L., C.Y.H.).
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  Data: <searchLink fieldCode="JN" term="%220147763%22">Circulation</searchLink> [Circulation] 2026 Apr 14; Vol. 153 (15), pp. 1104-1116. <i>Date of Electronic Publication: </i>2026 Mar 09.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Lippincott+Williams+%26+Wilkins%22">Lippincott Williams & Wilkins </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>0147763 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1524-4539 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2200097322%22">00097322 </searchLink><i>NLM ISO Abbreviation: </i>Circulation <i>Subsets: </i>MEDLINE
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