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Selective disruption of tau-SH3 interactions rescues seizure and sleep phenotypes.

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Title: Selective disruption of tau-SH3 interactions rescues seizure and sleep phenotypes.
Authors: Shandilya MCV; Department of Neurology, University of California, Los Angeles, California, 90095, USA., Koutures A; Department of Neurology, University of California, Los Angeles, California, 90095, USA., Addo-Osafo K; Department of Neurology, University of California, Los Angeles, California, 90095, USA., Hwang K; Department of Neurology, University of California, Los Angeles, California, 90095, USA., Vicente M; Department of Neurology, University of California, Los Angeles, California, 90095, USA., Ewens AN; Department of Pharmacology, University of Minnesota, Minneapolis, Minnesota, 55455, USA., Katz BM; Department of Neurology, University of California, Los Angeles, California, 90095, USA., Peters ST; Department of Neurology, University of Minnesota, Minneapolis, Minnesota, 55455, USA., Choquette JM; Department of Neurology, University of Minnesota, Minneapolis, Minnesota, 55455, USA., Vaknalli RN; Department of Neurology, University of California, Los Angeles, California, 90095, USA., Venkateswaran N; Department of Neurology, University of California, Los Angeles, California, 90095, USA., Onanyan N; Department of Neurology, University of California, Los Angeles, California, 90095, USA., Narasani A; Department of Neurology, University of California, Los Angeles, California, 90095, USA., Ravishankar S; Department of Neurology, University of California, Los Angeles, California, 90095, USA., Stepter J; Department of Neurology, University of California, Los Angeles, California, 90095, USA., Western A; Department of Neurology, University of California, Los Angeles, California, 90095, USA., Benneyworth MA; Department of Neuroscience, University of Minnesota, Minneapolis, Minnesota, 55455, USA., Cohn W; Department of Neurology, University of California, Los Angeles, California, 90095, USA., John V; Department of Neurology, University of California, Los Angeles, California, 90095, USA., Whitelegge JP; Pasarow Mass Spectrometry Laboratory, Jane and Terry Semel Institute for Neuroscience and Human Behavior, University of California, Los Angeles, California, 90095, USA., Vossel K; Department of Neurology, University of California, Los Angeles, California, 90095, USA.
Source: Brain : a journal of neurology [Brain] 2026 Mar 09. Date of Electronic Publication: 2026 Mar 09.
Publication Type: Journal Article
Journal Info: Publisher: Oxford University Press Country of Publication: England NLM ID: 0372537 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1460-2156 (Electronic) Linking ISSN: 00068950 NLM ISO Abbreviation: Brain Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Selective disruption of tau-SH3 interactions rescues seizure and sleep phenotypes.
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  Data: <searchLink fieldCode="AU" term="%22Shandilya+MCV%22">Shandilya MCV</searchLink>; Department of Neurology, University of California, Los Angeles, California, 90095, USA.<br /><searchLink fieldCode="AU" term="%22Koutures+A%22">Koutures A</searchLink>; Department of Neurology, University of California, Los Angeles, California, 90095, USA.<br /><searchLink fieldCode="AU" term="%22Addo-Osafo+K%22">Addo-Osafo K</searchLink>; Department of Neurology, University of California, Los Angeles, California, 90095, USA.<br /><searchLink fieldCode="AU" term="%22Hwang+K%22">Hwang K</searchLink>; Department of Neurology, University of California, Los Angeles, California, 90095, USA.<br /><searchLink fieldCode="AU" term="%22Vicente+M%22">Vicente M</searchLink>; Department of Neurology, University of California, Los Angeles, California, 90095, USA.<br /><searchLink fieldCode="AU" term="%22Ewens+AN%22">Ewens AN</searchLink>; Department of Pharmacology, University of Minnesota, Minneapolis, Minnesota, 55455, USA.<br /><searchLink fieldCode="AU" term="%22Katz+BM%22">Katz BM</searchLink>; Department of Neurology, University of California, Los Angeles, California, 90095, USA.<br /><searchLink fieldCode="AU" term="%22Peters+ST%22">Peters ST</searchLink>; Department of Neurology, University of Minnesota, Minneapolis, Minnesota, 55455, USA.<br /><searchLink fieldCode="AU" term="%22Choquette+JM%22">Choquette JM</searchLink>; Department of Neurology, University of Minnesota, Minneapolis, Minnesota, 55455, USA.<br /><searchLink fieldCode="AU" term="%22Vaknalli+RN%22">Vaknalli RN</searchLink>; Department of Neurology, University of California, Los Angeles, California, 90095, USA.<br /><searchLink fieldCode="AU" term="%22Venkateswaran+N%22">Venkateswaran N</searchLink>; Department of Neurology, University of California, Los Angeles, California, 90095, USA.<br /><searchLink fieldCode="AU" term="%22Onanyan+N%22">Onanyan N</searchLink>; Department of Neurology, University of California, Los Angeles, California, 90095, USA.<br /><searchLink fieldCode="AU" term="%22Narasani+A%22">Narasani A</searchLink>; Department of Neurology, University of California, Los Angeles, California, 90095, USA.<br /><searchLink fieldCode="AU" term="%22Ravishankar+S%22">Ravishankar S</searchLink>; Department of Neurology, University of California, Los Angeles, California, 90095, USA.<br /><searchLink fieldCode="AU" term="%22Stepter+J%22">Stepter J</searchLink>; Department of Neurology, University of California, Los Angeles, California, 90095, USA.<br /><searchLink fieldCode="AU" term="%22Western+A%22">Western A</searchLink>; Department of Neurology, University of California, Los Angeles, California, 90095, USA.<br /><searchLink fieldCode="AU" term="%22Benneyworth+MA%22">Benneyworth MA</searchLink>; Department of Neuroscience, University of Minnesota, Minneapolis, Minnesota, 55455, USA.<br /><searchLink fieldCode="AU" term="%22Cohn+W%22">Cohn W</searchLink>; Department of Neurology, University of California, Los Angeles, California, 90095, USA.<br /><searchLink fieldCode="AU" term="%22John+V%22">John V</searchLink>; Department of Neurology, University of California, Los Angeles, California, 90095, USA.<br /><searchLink fieldCode="AU" term="%22Whitelegge+JP%22">Whitelegge JP</searchLink>; Pasarow Mass Spectrometry Laboratory, Jane and Terry Semel Institute for Neuroscience and Human Behavior, University of California, Los Angeles, California, 90095, USA.<br /><searchLink fieldCode="AU" term="%22Vossel+K%22">Vossel K</searchLink>; Department of Neurology, University of California, Los Angeles, California, 90095, USA.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Oxford+University+Press%22">Oxford University Press </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>0372537 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1460-2156 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2200068950%22">00068950 </searchLink><i>NLM ISO Abbreviation: </i>Brain <i>Subsets: </i>MEDLINE
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        Value: 10.1093/brain/awag090
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        Text: English
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              Text: 2026 Mar 09
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