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Glycoside hydrolases enhance antibiotic activity against Pseudomonas aeruginosa biofilms from cystic fibrosis airways.

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Title: Glycoside hydrolases enhance antibiotic activity against Pseudomonas aeruginosa biofilms from cystic fibrosis airways.
Authors: Martin I; Division of Paediatric Respiratory Medicine, Department of Paediatrics, The Hospital for Sick Children, Toronto, Ontario, Canada.; Program in Translational Medicine, Peter Gilgan Center for Research and Learning, The Hospital for Sick Children, Toronto, Ontario, Canada., Chung J; Program in Translational Medicine, Peter Gilgan Center for Research and Learning, The Hospital for Sick Children, Toronto, Ontario, Canada.; Temerty Faculty of Medicine, University of Toronto, Toronto, Ontario, Canada., Raju D; Program in Molecular Medicine, Peter Gilgan Center for Research and Learning, The Hospital for Sick Children, Toronto, Ontario, Canada., Yau Y; Program in Translational Medicine, Peter Gilgan Center for Research and Learning, The Hospital for Sick Children, Toronto, Ontario, Canada., Morris AJ; Program in Translational Medicine, Peter Gilgan Center for Research and Learning, The Hospital for Sick Children, Toronto, Ontario, Canada.; Department of Cellular and Molecular Biology, University of Texas Health Science Center at Tyler, Tyler, Texas, USA., Eisha S; Program in Translational Medicine, Peter Gilgan Center for Research and Learning, The Hospital for Sick Children, Toronto, Ontario, Canada., Howell PL; Program in Molecular Medicine, Peter Gilgan Center for Research and Learning, The Hospital for Sick Children, Toronto, Ontario, Canada.; Department of Biochemistry, University of Toronto, Toronto, Ontario, Canada., Waters V; Program in Translational Medicine, Peter Gilgan Center for Research and Learning, The Hospital for Sick Children, Toronto, Ontario, Canada.; Division of Infectious Diseases, Department of Paediatrics, The Hospital for Sick Children, Toronto, Ontario, Canada.
Source: Microbiology spectrum [Microbiol Spectr] 2026 Apr 07; Vol. 14 (4), pp. e0135425. Date of Electronic Publication: 2026 Mar 09.
Publication Type: Journal Article
Journal Info: Publisher: ASM Press Country of Publication: United States NLM ID: 101634614 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2165-0497 (Electronic) Linking ISSN: 21650497 NLM ISO Abbreviation: Microbiol Spectr Subsets: MEDLINE
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  Data: Glycoside hydrolases enhance antibiotic activity against Pseudomonas aeruginosa biofilms from cystic fibrosis airways.
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  Data: <searchLink fieldCode="AU" term="%22Martin+I%22">Martin I</searchLink>; Division of Paediatric Respiratory Medicine, Department of Paediatrics, The Hospital for Sick Children, Toronto, Ontario, Canada.; Program in Translational Medicine, Peter Gilgan Center for Research and Learning, The Hospital for Sick Children, Toronto, Ontario, Canada.<br /><searchLink fieldCode="AU" term="%22Chung+J%22">Chung J</searchLink>; Program in Translational Medicine, Peter Gilgan Center for Research and Learning, The Hospital for Sick Children, Toronto, Ontario, Canada.; Temerty Faculty of Medicine, University of Toronto, Toronto, Ontario, Canada.<br /><searchLink fieldCode="AU" term="%22Raju+D%22">Raju D</searchLink>; Program in Molecular Medicine, Peter Gilgan Center for Research and Learning, The Hospital for Sick Children, Toronto, Ontario, Canada.<br /><searchLink fieldCode="AU" term="%22Yau+Y%22">Yau Y</searchLink>; Program in Translational Medicine, Peter Gilgan Center for Research and Learning, The Hospital for Sick Children, Toronto, Ontario, Canada.<br /><searchLink fieldCode="AU" term="%22Morris+AJ%22">Morris AJ</searchLink>; Program in Translational Medicine, Peter Gilgan Center for Research and Learning, The Hospital for Sick Children, Toronto, Ontario, Canada.; Department of Cellular and Molecular Biology, University of Texas Health Science Center at Tyler, Tyler, Texas, USA.<br /><searchLink fieldCode="AU" term="%22Eisha+S%22">Eisha S</searchLink>; Program in Translational Medicine, Peter Gilgan Center for Research and Learning, The Hospital for Sick Children, Toronto, Ontario, Canada.<br /><searchLink fieldCode="AU" term="%22Howell+PL%22">Howell PL</searchLink>; Program in Molecular Medicine, Peter Gilgan Center for Research and Learning, The Hospital for Sick Children, Toronto, Ontario, Canada.; Department of Biochemistry, University of Toronto, Toronto, Ontario, Canada.<br /><searchLink fieldCode="AU" term="%22Waters+V%22">Waters V</searchLink>; Program in Translational Medicine, Peter Gilgan Center for Research and Learning, The Hospital for Sick Children, Toronto, Ontario, Canada.; Division of Infectious Diseases, Department of Paediatrics, The Hospital for Sick Children, Toronto, Ontario, Canada.
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        Value: 10.1128/spectrum.01354-25
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      – TitleFull: Glycoside hydrolases enhance antibiotic activity against Pseudomonas aeruginosa biofilms from cystic fibrosis airways.
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              Text: 2026 Apr 07
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