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SPICE-GRADE: simultaneous processing of indirect causal evidence in complex pathways using GRADE - an exploratory case study.

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Title: SPICE-GRADE: simultaneous processing of indirect causal evidence in complex pathways using GRADE - an exploratory case study.
Authors: Eachempati P; MAGIC Evidence Ecosystem Foundation, Oslo, Norway; Faculty of Dentistry, Peninsula Dental School, University of Plymouth, UK; Manipal University College Malaysia, Melaka, Malaysia. Electronic address: prashanti@magicevidence.org., Guyatt G; MAGIC Evidence Ecosystem Foundation, Oslo, Norway; Department of Health Research Methods, Evidence, and Impact, McMaster University, Hamilton, Ontario, Canada; Department of Medicine, McMaster University, Hamilton, Ontario, L8S4L8, Canada., Vandvik PO; MAGIC Evidence Ecosystem Foundation, Oslo, Norway; Institute of Health and Society, University of Oslo Faculty of Medicine, Oslo, Norway., Guerin PJ; WorldWide Antimalarial Resistance Network (WWARN), Infectious Diseases Data Observatory (IDDO), Nuffield Department of Medicine, Oxford University, Oxford, UK., Dahal P; Department of Statistics and Sciences, Infectious Diseases Data Observatory (IDDO), Big Data Institute Building, University of Oxford, Oxford, UK., Barnes KI; WorldWide Antimalarial Resistance Network (WWARN), Infectious Diseases Data Observatory (IDDO), Nuffield Department of Medicine, Oxford University, Oxford, UK; Division of Clinical Pharmacology, Department of Medicine, University of Cape Town, Cape Town, South Africa., Agoritsas T; Division of General Internal Medicine, University Hospitals of Geneva, Geneva, Switzerland; MAGIC Evidence Ecosystem Foundation, Oslo, Norway; Department of Health Research Methods, Evidence, and Impact, McMaster University, Hamilton, Ontario, Canada.
Source: Journal of clinical epidemiology [J Clin Epidemiol] 2026 Jun; Vol. 194, pp. 112219. Date of Electronic Publication: 2026 Mar 07.
Publication Type: Journal Article
Journal Info: Publisher: Elsevier Country of Publication: United States NLM ID: 8801383 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1878-5921 (Electronic) Linking ISSN: 08954356 NLM ISO Abbreviation: J Clin Epidemiol Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: <searchLink fieldCode="AU" term="%22Eachempati+P%22">Eachempati P</searchLink>; MAGIC Evidence Ecosystem Foundation, Oslo, Norway; Faculty of Dentistry, Peninsula Dental School, University of Plymouth, UK; Manipal University College Malaysia, Melaka, Malaysia. Electronic address: prashanti@magicevidence.org.<br /><searchLink fieldCode="AU" term="%22Guyatt+G%22">Guyatt G</searchLink>; MAGIC Evidence Ecosystem Foundation, Oslo, Norway; Department of Health Research Methods, Evidence, and Impact, McMaster University, Hamilton, Ontario, Canada; Department of Medicine, McMaster University, Hamilton, Ontario, L8S4L8, Canada.<br /><searchLink fieldCode="AU" term="%22Vandvik+PO%22">Vandvik PO</searchLink>; MAGIC Evidence Ecosystem Foundation, Oslo, Norway; Institute of Health and Society, University of Oslo Faculty of Medicine, Oslo, Norway.<br /><searchLink fieldCode="AU" term="%22Guerin+PJ%22">Guerin PJ</searchLink>; WorldWide Antimalarial Resistance Network (WWARN), Infectious Diseases Data Observatory (IDDO), Nuffield Department of Medicine, Oxford University, Oxford, UK.<br /><searchLink fieldCode="AU" term="%22Dahal+P%22">Dahal P</searchLink>; Department of Statistics and Sciences, Infectious Diseases Data Observatory (IDDO), Big Data Institute Building, University of Oxford, Oxford, UK.<br /><searchLink fieldCode="AU" term="%22Barnes+KI%22">Barnes KI</searchLink>; WorldWide Antimalarial Resistance Network (WWARN), Infectious Diseases Data Observatory (IDDO), Nuffield Department of Medicine, Oxford University, Oxford, UK; Division of Clinical Pharmacology, Department of Medicine, University of Cape Town, Cape Town, South Africa.<br /><searchLink fieldCode="AU" term="%22Agoritsas+T%22">Agoritsas T</searchLink>; Division of General Internal Medicine, University Hospitals of Geneva, Geneva, Switzerland; MAGIC Evidence Ecosystem Foundation, Oslo, Norway; Department of Health Research Methods, Evidence, and Impact, McMaster University, Hamilton, Ontario, Canada.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Elsevier%22">Elsevier </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>8801383 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1878-5921 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2208954356%22">08954356 </searchLink><i>NLM ISO Abbreviation: </i>J Clin Epidemiol <i>Subsets: </i>MEDLINE
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        Value: 10.1016/j.jclinepi.2026.112219
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              Text: 2026 Jun
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