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Donidalorsen for hereditary angioedema: Long-term results from a 4-year, phase 2, open-label extension study.

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Title: Donidalorsen for hereditary angioedema: Long-term results from a 4-year, phase 2, open-label extension study.
Authors: Manning ME; Medical Research of Arizona, Scottsdale, Arizona., de Lange M; Department of Vascular Medicine, Amsterdam Cardiovascular Sciences, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands., Bernstein JA; Division of Rheumatology, Allergy, and Immunology, Department of Internal Medicine, University of Cincinnati College of Medicine, Cincinnati, Ohio; Bernstein Clinical Research Center, LLC, Cincinnati, Ohio., Craig T; Departments of Medicine, Pediatrics, Obstetrics and Gynecology, Maternal-Fetal Medicine, and Biomedical Sciences, Penn State University, Hershey, Pennsylvania; Vinmec International Hospital, Times City, Hanoi, Vietnam; College of Health Sciences, VinUniversity, Hanoi, Vietnam., Lumry WR; Asthma and Allergy Research Associates, Dallas, Texas., Raasch J; Midwest Immunology Clinic, Plymouth, Minnesota., Tachdjian R; Division of Allergy, Immunology, and Rheumatology, University of California, Los Angeles, Los Angeles, California., Bordone L; Ionis, Carlsbad, California., Deng Y; Ionis, Carlsbad, California., Newman KB; Ionis, Carlsbad, California., Cohn DM; Department of Vascular Medicine, Amsterdam Cardiovascular Sciences, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands. Electronic address: d.m.cohn@amsterdamumc.nl.
Source: Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology [Ann Allergy Asthma Immunol] 2026 Jun; Vol. 136 (6), pp. 699-705.e1. Date of Electronic Publication: 2026 Mar 07.
Publication Type: Journal Article; Clinical Trial, Phase II; Multicenter Study
Journal Info: Publisher: American College of Allergy, Asthma, and Immunology Country of Publication: United States NLM ID: 9503580 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1534-4436 (Electronic) Linking ISSN: 10811206 NLM ISO Abbreviation: Ann Allergy Asthma Immunol Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Donidalorsen for hereditary angioedema: Long-term results from a 4-year, phase 2, open-label extension study.
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  Data: <searchLink fieldCode="AU" term="%22Manning+ME%22">Manning ME</searchLink>; Medical Research of Arizona, Scottsdale, Arizona.<br /><searchLink fieldCode="AU" term="%22de+Lange+M%22">de Lange M</searchLink>; Department of Vascular Medicine, Amsterdam Cardiovascular Sciences, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Bernstein+JA%22">Bernstein JA</searchLink>; Division of Rheumatology, Allergy, and Immunology, Department of Internal Medicine, University of Cincinnati College of Medicine, Cincinnati, Ohio; Bernstein Clinical Research Center, LLC, Cincinnati, Ohio.<br /><searchLink fieldCode="AU" term="%22Craig+T%22">Craig T</searchLink>; Departments of Medicine, Pediatrics, Obstetrics and Gynecology, Maternal-Fetal Medicine, and Biomedical Sciences, Penn State University, Hershey, Pennsylvania; Vinmec International Hospital, Times City, Hanoi, Vietnam; College of Health Sciences, VinUniversity, Hanoi, Vietnam.<br /><searchLink fieldCode="AU" term="%22Lumry+WR%22">Lumry WR</searchLink>; Asthma and Allergy Research Associates, Dallas, Texas.<br /><searchLink fieldCode="AU" term="%22Raasch+J%22">Raasch J</searchLink>; Midwest Immunology Clinic, Plymouth, Minnesota.<br /><searchLink fieldCode="AU" term="%22Tachdjian+R%22">Tachdjian R</searchLink>; Division of Allergy, Immunology, and Rheumatology, University of California, Los Angeles, Los Angeles, California.<br /><searchLink fieldCode="AU" term="%22Bordone+L%22">Bordone L</searchLink>; Ionis, Carlsbad, California.<br /><searchLink fieldCode="AU" term="%22Deng+Y%22">Deng Y</searchLink>; Ionis, Carlsbad, California.<br /><searchLink fieldCode="AU" term="%22Newman+KB%22">Newman KB</searchLink>; Ionis, Carlsbad, California.<br /><searchLink fieldCode="AU" term="%22Cohn+DM%22">Cohn DM</searchLink>; Department of Vascular Medicine, Amsterdam Cardiovascular Sciences, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands. Electronic address: d.m.cohn@amsterdamumc.nl.
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  Data: <searchLink fieldCode="JN" term="%229503580%22">Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology</searchLink> [Ann Allergy Asthma Immunol] 2026 Jun; Vol. 136 (6), pp. 699-705.e1. <i>Date of Electronic Publication: </i>2026 Mar 07.
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