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IFN-gene signatures in B cells following influenza A and B virus infection and influenza vaccination.

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Title: IFN-gene signatures in B cells following influenza A and B virus infection and influenza vaccination.
Authors: Zhang W; Department of Microbiology and Immunology, University of Melbourne, at the Peter Doherty Institute for Infection and Immunity, Parkville, VIC, 3010, Australia.; HKU-Pasteur Research Pole, School of Public Health, LKS Faculty of Medicine, The University of Hong Kong, Hong Kong SAR, China., Allen EK; Department of Immunology, St. Jude Children's Research Hospital, Memphis, TN, 38105, USA., Li S; Computational Sciences Initiative, Department of Immunology and Microbiology, University of Melbourne, at the Peter Doherty Institute for Infection and Immunity, Melbourne, VIC, 3000, Australia., Tarasova I; Bioinformatics Division, Walter and Eliza Hall Institute of Medical Research, Parkville, VIC, 3052, Australia., Farrukee R; Department of Microbiology and Immunology, University of Melbourne, at the Peter Doherty Institute for Infection and Immunity, Parkville, VIC, 3010, Australia., Kedzierski L; Department of Microbiology and Immunology, University of Melbourne, at the Peter Doherty Institute for Infection and Immunity, Parkville, VIC, 3010, Australia., Gilbertson B; Department of Microbiology and Immunology, University of Melbourne, at the Peter Doherty Institute for Infection and Immunity, Parkville, VIC, 3010, Australia., McQuilten HA; Department of Microbiology and Immunology, University of Melbourne, at the Peter Doherty Institute for Infection and Immunity, Parkville, VIC, 3010, Australia., Habel JR; Department of Microbiology and Immunology, University of Melbourne, at the Peter Doherty Institute for Infection and Immunity, Parkville, VIC, 3010, Australia., Allen LF; Department of Microbiology and Immunology, University of Melbourne, at the Peter Doherty Institute for Infection and Immunity, Parkville, VIC, 3010, Australia., Rockman S; Department of Microbiology and Immunology, University of Melbourne, at the Peter Doherty Institute for Infection and Immunity, Parkville, VIC, 3010, Australia.; Vaccine Product Development, CSL Seqirus Ltd, Parkville, VIC, 3052, Australia., Londrigan SL; Department of Microbiology and Immunology, University of Melbourne, at the Peter Doherty Institute for Infection and Immunity, Parkville, VIC, 3010, Australia., Kent SJ; Department of Microbiology and Immunology, University of Melbourne, at the Peter Doherty Institute for Infection and Immunity, Parkville, VIC, 3010, Australia., Wheatley AK; Department of Microbiology and Immunology, University of Melbourne, at the Peter Doherty Institute for Infection and Immunity, Parkville, VIC, 3010, Australia., Trubiano JA; Department of Infectious Diseases, University of Melbourne, at the Peter Doherty Institute for Infection and Immunity, Melbourne, VIC, 3000, Australia.; Department of Infectious Diseases, Centre for Antibiotic Allergy and Research, Austin Health, Heidelberg, VIC, 3084, Australia.; Department of Infectious Diseases, Peter MacCallum Cancer Centre, Melbourne, VIC, 3000, Australia.; National Centre for Infections in Cancer, Peter McCallum Cancer Centre, Melbourne, 3000, VIC, Australia., Kotsimbos TC; Department of Respiratory Medicine, The Alfred Hospital, Melbourne, 3004, VIC, Australia.; Department of Medicine, Central Clinical School, The Alfred Hospital, Monash University, Melbourne, 3004, VIC, Australia., Cheng AC; School of Public Health and Preventive Medicine, Monash University, Clayton, 3800, VIC, Australia.; Monash Infectious Diseases, Monash Health and School of Clinical Sciences, Monash University, Clayton, 3168, VIC, Australia., Schroeder J; Computational Sciences Initiative, Department of Immunology and Microbiology, University of Melbourne, at the Peter Doherty Institute for Infection and Immunity, Melbourne, VIC, 3000, Australia., Crawford JC; Department of Host-Microbe Interactions, St. Jude Children's Research Hospital, Memphis, 38105, TN, USA., Thomas PG; Immunology and Vaccine Development Program, Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Center, Seattle, 98109, WA, USA., Kedzierska K; Department of Microbiology and Immunology, University of Melbourne, at the Peter Doherty Institute for Infection and Immunity, Parkville, VIC, 3010, Australia. kkedz@unimelb.edu.au., Nguyen THO; Department of Microbiology and Immunology, University of Melbourne, at the Peter Doherty Institute for Infection and Immunity, Parkville, VIC, 3010, Australia. thonguyen@unimelb.edu.au.
Source: EMBO molecular medicine [EMBO Mol Med] 2026 Apr; Vol. 18 (4), pp. 1456-1477. Date of Electronic Publication: 2026 Mar 09.
Publication Type: Journal Article
Journal Info: Publisher: EMBO Press Country of Publication: Germany NLM ID: 101487380 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1757-4684 (Electronic) Linking ISSN: 17574676 NLM ISO Abbreviation: EMBO Mol Med Subsets: MEDLINE
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  Data: IFN-gene signatures in B cells following influenza A and B virus infection and influenza vaccination.
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  Data: <searchLink fieldCode="AU" term="%22Zhang+W%22">Zhang W</searchLink>; Department of Microbiology and Immunology, University of Melbourne, at the Peter Doherty Institute for Infection and Immunity, Parkville, VIC, 3010, Australia.; HKU-Pasteur Research Pole, School of Public Health, LKS Faculty of Medicine, The University of Hong Kong, Hong Kong SAR, China.<br /><searchLink fieldCode="AU" term="%22Allen+EK%22">Allen EK</searchLink>; Department of Immunology, St. Jude Children's Research Hospital, Memphis, TN, 38105, USA.<br /><searchLink fieldCode="AU" term="%22Li+S%22">Li S</searchLink>; Computational Sciences Initiative, Department of Immunology and Microbiology, University of Melbourne, at the Peter Doherty Institute for Infection and Immunity, Melbourne, VIC, 3000, Australia.<br /><searchLink fieldCode="AU" term="%22Tarasova+I%22">Tarasova I</searchLink>; Bioinformatics Division, Walter and Eliza Hall Institute of Medical Research, Parkville, VIC, 3052, Australia.<br /><searchLink fieldCode="AU" term="%22Farrukee+R%22">Farrukee R</searchLink>; Department of Microbiology and Immunology, University of Melbourne, at the Peter Doherty Institute for Infection and Immunity, Parkville, VIC, 3010, Australia.<br /><searchLink fieldCode="AU" term="%22Kedzierski+L%22">Kedzierski L</searchLink>; Department of Microbiology and Immunology, University of Melbourne, at the Peter Doherty Institute for Infection and Immunity, Parkville, VIC, 3010, Australia.<br /><searchLink fieldCode="AU" term="%22Gilbertson+B%22">Gilbertson B</searchLink>; Department of Microbiology and Immunology, University of Melbourne, at the Peter Doherty Institute for Infection and Immunity, Parkville, VIC, 3010, Australia.<br /><searchLink fieldCode="AU" term="%22McQuilten+HA%22">McQuilten HA</searchLink>; Department of Microbiology and Immunology, University of Melbourne, at the Peter Doherty Institute for Infection and Immunity, Parkville, VIC, 3010, Australia.<br /><searchLink fieldCode="AU" term="%22Habel+JR%22">Habel JR</searchLink>; Department of Microbiology and Immunology, University of Melbourne, at the Peter Doherty Institute for Infection and Immunity, Parkville, VIC, 3010, Australia.<br /><searchLink fieldCode="AU" term="%22Allen+LF%22">Allen LF</searchLink>; Department of Microbiology and Immunology, University of Melbourne, at the Peter Doherty Institute for Infection and Immunity, Parkville, VIC, 3010, Australia.<br /><searchLink fieldCode="AU" term="%22Rockman+S%22">Rockman S</searchLink>; Department of Microbiology and Immunology, University of Melbourne, at the Peter Doherty Institute for Infection and Immunity, Parkville, VIC, 3010, Australia.; Vaccine Product Development, CSL Seqirus Ltd, Parkville, VIC, 3052, Australia.<br /><searchLink fieldCode="AU" term="%22Londrigan+SL%22">Londrigan SL</searchLink>; Department of Microbiology and Immunology, University of Melbourne, at the Peter Doherty Institute for Infection and Immunity, Parkville, VIC, 3010, Australia.<br /><searchLink fieldCode="AU" term="%22Kent+SJ%22">Kent SJ</searchLink>; Department of Microbiology and Immunology, University of Melbourne, at the Peter Doherty Institute for Infection and Immunity, Parkville, VIC, 3010, Australia.<br /><searchLink fieldCode="AU" term="%22Wheatley+AK%22">Wheatley AK</searchLink>; Department of Microbiology and Immunology, University of Melbourne, at the Peter Doherty Institute for Infection and Immunity, Parkville, VIC, 3010, Australia.<br /><searchLink fieldCode="AU" term="%22Trubiano+JA%22">Trubiano JA</searchLink>; Department of Infectious Diseases, University of Melbourne, at the Peter Doherty Institute for Infection and Immunity, Melbourne, VIC, 3000, Australia.; Department of Infectious Diseases, Centre for Antibiotic Allergy and Research, Austin Health, Heidelberg, VIC, 3084, Australia.; Department of Infectious Diseases, Peter MacCallum Cancer Centre, Melbourne, VIC, 3000, Australia.; National Centre for Infections in Cancer, Peter McCallum Cancer Centre, Melbourne, 3000, VIC, Australia.<br /><searchLink fieldCode="AU" term="%22Kotsimbos+TC%22">Kotsimbos TC</searchLink>; Department of Respiratory Medicine, The Alfred Hospital, Melbourne, 3004, VIC, Australia.; Department of Medicine, Central Clinical School, The Alfred Hospital, Monash University, Melbourne, 3004, VIC, Australia.<br /><searchLink fieldCode="AU" term="%22Cheng+AC%22">Cheng AC</searchLink>; School of Public Health and Preventive Medicine, Monash University, Clayton, 3800, VIC, Australia.; Monash Infectious Diseases, Monash Health and School of Clinical Sciences, Monash University, Clayton, 3168, VIC, Australia.<br /><searchLink fieldCode="AU" term="%22Schroeder+J%22">Schroeder J</searchLink>; Computational Sciences Initiative, Department of Immunology and Microbiology, University of Melbourne, at the Peter Doherty Institute for Infection and Immunity, Melbourne, VIC, 3000, Australia.<br /><searchLink fieldCode="AU" term="%22Crawford+JC%22">Crawford JC</searchLink>; Department of Host-Microbe Interactions, St. Jude Children's Research Hospital, Memphis, 38105, TN, USA.<br /><searchLink fieldCode="AU" term="%22Thomas+PG%22">Thomas PG</searchLink>; Immunology and Vaccine Development Program, Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Center, Seattle, 98109, WA, USA.<br /><searchLink fieldCode="AU" term="%22Kedzierska+K%22">Kedzierska K</searchLink>; Department of Microbiology and Immunology, University of Melbourne, at the Peter Doherty Institute for Infection and Immunity, Parkville, VIC, 3010, Australia. kkedz@unimelb.edu.au.<br /><searchLink fieldCode="AU" term="%22Nguyen+THO%22">Nguyen THO</searchLink>; Department of Microbiology and Immunology, University of Melbourne, at the Peter Doherty Institute for Infection and Immunity, Parkville, VIC, 3010, Australia. thonguyen@unimelb.edu.au.
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  Data: <searchLink fieldCode="JN" term="%22101487380%22">EMBO molecular medicine</searchLink> [EMBO Mol Med] 2026 Apr; Vol. 18 (4), pp. 1456-1477. <i>Date of Electronic Publication: </i>2026 Mar 09.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22EMBO+Press%22">EMBO Press </searchLink><i>Country of Publication: </i>Germany <i>NLM ID: </i>101487380 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1757-4684 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2217574676%22">17574676 </searchLink><i>NLM ISO Abbreviation: </i>EMBO Mol Med <i>Subsets: </i>MEDLINE
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