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Low-dose radiotherapy remodels the tumor immune microenvironment via the cGAS-STING pathway: mechanisms, challenges, and combination therapy strategies.

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Bibliographic Details
Title: Low-dose radiotherapy remodels the tumor immune microenvironment via the cGAS-STING pathway: mechanisms, challenges, and combination therapy strategies.
Authors: He Y; West China School of Medicine, Sichuan University, Chengdu, 610041, Sichuan Province, China., Zeng X; Department of Radiotherapy Physics & Technology, West China Hospital, Sichuan University, Cancer Center, Chengdu, 610041, Sichuan Province, China., Liu Q; West China School of Medicine, Sichuan University, Chengdu, 610041, Sichuan Province, China., Zhou L; West China School of Medicine, Sichuan University, Chengdu, 610041, Sichuan Province, China., Tang Y; West China School of Medicine, Sichuan University, Chengdu, 610041, Sichuan Province, China., Liu S; West China School of Medicine, Sichuan University, Chengdu, 610041, Sichuan Province, China., Wang X; West China School of Medicine, Sichuan University, Chengdu, 610041, Sichuan Province, China., Shen S; West China School of Medicine, Sichuan University, Chengdu, 610041, Sichuan Province, China., Ji J; West China School of Medicine, Sichuan University, Chengdu, 610041, Sichuan Province, China., Liu Z; Department of Radiotherapy Physics & Technology, West China Hospital, Sichuan University, Cancer Center, Chengdu, 610041, Sichuan Province, China., Li J; Division of Thoracic Tumor Multimodality Treatment, West China Hospital, Sichuan University, Cancer Center, Chengdu, 610041, Sichuan Province, China. lijiangping@wchscu.cn.
Source: Molecular cancer [Mol Cancer] 2026 Mar 10; Vol. 25 (1). Date of Electronic Publication: 2026 Mar 10.
Publication Type: Journal Article; Review
Journal Info: Publisher: BioMed Central Country of Publication: England NLM ID: 101147698 Publication Model: Electronic Cited Medium: Internet ISSN: 1476-4598 (Electronic) Linking ISSN: 14764598 NLM ISO Abbreviation: Mol Cancer Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1476-4598
DOI:10.1186/s12943-026-02634-5