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Clinical Validation of AI-Assisted Evaluation of Indeterminate Biliary Strictures in Digital-Single Operator Cholangioscopy: A Transcontinental Multicentric Study.

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Title: Clinical Validation of AI-Assisted Evaluation of Indeterminate Biliary Strictures in Digital-Single Operator Cholangioscopy: A Transcontinental Multicentric Study.
Authors: Mascarenhas M; Gastroenterology Department, Centro Hospitalar Universitario de São João, Porto, Portugal.; WGO Gastroenterology and Hepatology Training Center, Porto, Portugal.; Department of Medicine, Faculty of Medicine of the University of Porto, Porto, Portugal., Widmer J; Division of Gastroenterology, NYU Langone Health, New York, New York, USA., Mendes F; Gastroenterology Department, Centro Hospitalar Universitario de São João, Porto, Portugal.; WGO Gastroenterology and Hepatology Training Center, Porto, Portugal.; Department of Medicine, Faculty of Medicine of the University of Porto, Porto, Portugal., Ribeiro T; Gastroenterology Department, Centro Hospitalar Universitario de São João, Porto, Portugal.; WGO Gastroenterology and Hepatology Training Center, Porto, Portugal.; Department of Medicine, Faculty of Medicine of the University of Porto, Porto, Portugal., Pinto da Costa A; Gastroenterology Department, Hospital Universitario Puerta de Hierro Majadahonda, Madrid, Spain., Agudo B; Gastroenterology Department, Hospital Universitario Puerta de Hierro Majadahonda, Madrid, Spain., Martins M; Gastroenterology Department, Centro Hospitalar Universitario de São João, Porto, Portugal.; WGO Gastroenterology and Hepatology Training Center, Porto, Portugal.; Department of Medicine, Faculty of Medicine of the University of Porto, Porto, Portugal., Afonso J; Gastroenterology Department, Centro Hospitalar Universitario de São João, Porto, Portugal.; WGO Gastroenterology and Hepatology Training Center, Porto, Portugal.; Department of Medicine, Faculty of Medicine of the University of Porto, Porto, Portugal., Mota J; Gastroenterology Department, Centro Hospitalar Universitario de São João, Porto, Portugal.; WGO Gastroenterology and Hepatology Training Center, Porto, Portugal.; Department of Medicine, Faculty of Medicine of the University of Porto, Porto, Portugal., Almeida MJ; Gastroenterology Department, Centro Hospitalar Universitario de São João, Porto, Portugal.; WGO Gastroenterology and Hepatology Training Center, Porto, Portugal.; Department of Medicine, Faculty of Medicine of the University of Porto, Porto, Portugal., Cardoso P; Gastroenterology Department, Centro Hospitalar Universitario de São João, Porto, Portugal.; WGO Gastroenterology and Hepatology Training Center, Porto, Portugal.; Department of Medicine, Faculty of Medicine of the University of Porto, Porto, Portugal., Frias J; Gastroenterology Department, Centro Hospitalar Universitario de São João, Porto, Portugal.; WGO Gastroenterology and Hepatology Training Center, Porto, Portugal.; Department of Medicine, Faculty of Medicine of the University of Porto, Porto, Portugal., Araújo C; Gastroenterology Department, Centro Hospitalar Universitario de São João, Porto, Portugal.; WGO Gastroenterology and Hepatology Training Center, Porto, Portugal.; Department of Medicine, Faculty of Medicine of the University of Porto, Porto, Portugal., Cardoso H; Gastroenterology Department, Centro Hospitalar Universitario de São João, Porto, Portugal.; WGO Gastroenterology and Hepatology Training Center, Porto, Portugal.; Department of Medicine, Faculty of Medicine of the University of Porto, Porto, Portugal., Plaza González M; Gastroenterology Department, Hospital Universitario Puerta de Hierro Majadahonda, Madrid, Spain., Pérez-González A; Gastroenterology Department, Hospital Universitario Puerta de Hierro Majadahonda, Madrid, Spain., Lera Dos Santos ME; Digestive Endoscopy Department, Hospital das Clínicas da Faculdade de Medicina da Universidade de Sao Paulo, São Paulo, Brazil.; Digestive Endoscopy Department, Hospital São Luiz Jabaquara, São Paulo, Brazil., Moris M; Gastroenterology Department, Hospital Universitario Marques de Valdecilla, Santander, Spain., Garcia de Paredes AG; Gastroenterology Deparment, Hospital Universitario Ramon y Cajal, Madrid, Spain., Foruny J; Gastroenterology Deparment, Hospital Universitario Ramon y Cajal, Madrid, Spain., Bicudo de Oliveira L; Digestive Endoscopy Department, Hospital das Clínicas da Faculdade de Medicina da Universidade de Sao Paulo, São Paulo, Brazil., Ferreira de Carvalho M; Digestive Endoscopy Department, Hospital das Clínicas da Faculdade de Medicina da Universidade de Sao Paulo, São Paulo, Brazil., Maluf-Filho F; Digestive Endoscopy Department, Hospital das Clínicas da Faculdade de Medicina da Universidade de Sao Paulo, São Paulo, Brazil.; São Paulo State Cancer Institute, Universidade de Sao Paulo, São Paulo, Brazil., Ferreira MC; Gastrointestinal Endoscopy Department, Hospital Nove de Julho, São Paulo, Brazil., Prince T; Digestive Endoscopy Department, Hospital das Clínicas da Faculdade de Medicina da Universidade de Sao Paulo, São Paulo, Brazil.; Gastrointestinal Endoscopy Department, Hospital Nove de Julho, São Paulo, Brazil., Velasquez A; Gastrointestinal Endoscopy Department, Clínica Universitaria Colombia, Bogotá, Colombia., González IE; Gastrointestinal Endoscopy Department, Clínica Universitaria Colombia, Bogotá, Colombia., Ferreira J; Department of Mechanical Engineering, Faculty of Engineering of the University of Porto, Porto, Portugal., Kim GE; Center for Endoscopic Research and Therapeutics, University of Chicago Medicine, Chicago, Illinois, USA., Siddiqui UD; Center for Endoscopic Research and Therapeutics, University of Chicago Medicine, Chicago, Illinois, USA., Omrani LR; Division of Gastroenterology, NYU Langone Health, New York, New York, USA., Alrossais N MD; Department of Gastroenterology, King Faisal Specialist Hospital and Research Centre, Riyadh, Saudi Arabia., Keegan M; Gastrointestinal Endoscopy Department, Northern Beaches Hospital, Sydney, Australia., Aslam P; Gastrointestinal Endoscopy Department, Camberra Hospital, Camberra, Australia., Aggarwal V; Gastrointestinal Endoscopy Department, Camberra Hospital, Camberra, Australia., Vilas-Boas F; Gastroenterology Department, Centro Hospitalar Universitario de São João, Porto, Portugal.; WGO Gastroenterology and Hepatology Training Center, Porto, Portugal.; Department of Medicine, Faculty of Medicine of the University of Porto, Porto, Portugal., Pereira P; Gastroenterology Department, Centro Hospitalar Universitario de São João, Porto, Portugal.; WGO Gastroenterology and Hepatology Training Center, Porto, Portugal.; Department of Medicine, Faculty of Medicine of the University of Porto, Porto, Portugal., Sabbagh LC; Gastrointestinal Endoscopy Department, Clínica Universitaria Colombia, Bogotá, Colombia., Almuhaidb A; Department of Gastroenterology, King Faisal Specialist Hospital and Research Centre, Riyadh, Saudi Arabia., Guimarães Hourneaux De Moura E; Digestive Endoscopy Department, Hospital das Clínicas da Faculdade de Medicina da Universidade de Sao Paulo, São Paulo, Brazil.; Gastrointestinal Endoscopy Department, Hospital Vila Nova Star, São Paulo, Brazil ., Macedo G; Gastroenterology Department, Centro Hospitalar Universitario de São João, Porto, Portugal.; WGO Gastroenterology and Hepatology Training Center, Porto, Portugal.; Department of Medicine, Faculty of Medicine of the University of Porto, Porto, Portugal., González-Haba M; Gastroenterology Department, Hospital Universitario Puerta de Hierro Majadahonda, Madrid, Spain.
Source: Clinical and translational gastroenterology [Clin Transl Gastroenterol] 2026 Jun 01; Vol. 17 (6), pp. e01015. Date of Electronic Publication: 2026 Jun 01.
Publication Type: Journal Article; Multicenter Study; Validation Study
Journal Info: Publisher: Wolters Kluwer Health Country of Publication: United States NLM ID: 101532142 Publication Model: Electronic Cited Medium: Internet ISSN: 2155-384X (Electronic) Linking ISSN: 2155384X NLM ISO Abbreviation: Clin Transl Gastroenterol Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Clinical Validation of AI-Assisted Evaluation of Indeterminate Biliary Strictures in Digital-Single Operator Cholangioscopy: A Transcontinental Multicentric Study.
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  Label: Authors
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  Data: <searchLink fieldCode="AU" term="%22Mascarenhas+M%22">Mascarenhas M</searchLink>; Gastroenterology Department, Centro Hospitalar Universitario de São João, Porto, Portugal.; WGO Gastroenterology and Hepatology Training Center, Porto, Portugal.; Department of Medicine, Faculty of Medicine of the University of Porto, Porto, Portugal.<br /><searchLink fieldCode="AU" term="%22Widmer+J%22">Widmer J</searchLink>; Division of Gastroenterology, NYU Langone Health, New York, New York, USA.<br /><searchLink fieldCode="AU" term="%22Mendes+F%22">Mendes F</searchLink>; Gastroenterology Department, Centro Hospitalar Universitario de São João, Porto, Portugal.; WGO Gastroenterology and Hepatology Training Center, Porto, Portugal.; Department of Medicine, Faculty of Medicine of the University of Porto, Porto, Portugal.<br /><searchLink fieldCode="AU" term="%22Ribeiro+T%22">Ribeiro T</searchLink>; Gastroenterology Department, Centro Hospitalar Universitario de São João, Porto, Portugal.; WGO Gastroenterology and Hepatology Training Center, Porto, Portugal.; Department of Medicine, Faculty of Medicine of the University of Porto, Porto, Portugal.<br /><searchLink fieldCode="AU" term="%22Pinto+da+Costa+A%22">Pinto da Costa A</searchLink>; Gastroenterology Department, Hospital Universitario Puerta de Hierro Majadahonda, Madrid, Spain.<br /><searchLink fieldCode="AU" term="%22Agudo+B%22">Agudo B</searchLink>; Gastroenterology Department, Hospital Universitario Puerta de Hierro Majadahonda, Madrid, Spain.<br /><searchLink fieldCode="AU" term="%22Martins+M%22">Martins M</searchLink>; Gastroenterology Department, Centro Hospitalar Universitario de São João, Porto, Portugal.; WGO Gastroenterology and Hepatology Training Center, Porto, Portugal.; Department of Medicine, Faculty of Medicine of the University of Porto, Porto, Portugal.<br /><searchLink fieldCode="AU" term="%22Afonso+J%22">Afonso J</searchLink>; Gastroenterology Department, Centro Hospitalar Universitario de São João, Porto, Portugal.; WGO Gastroenterology and Hepatology Training Center, Porto, Portugal.; Department of Medicine, Faculty of Medicine of the University of Porto, Porto, Portugal.<br /><searchLink fieldCode="AU" term="%22Mota+J%22">Mota J</searchLink>; Gastroenterology Department, Centro Hospitalar Universitario de São João, Porto, Portugal.; WGO Gastroenterology and Hepatology Training Center, Porto, Portugal.; Department of Medicine, Faculty of Medicine of the University of Porto, Porto, Portugal.<br /><searchLink fieldCode="AU" term="%22Almeida+MJ%22">Almeida MJ</searchLink>; Gastroenterology Department, Centro Hospitalar Universitario de São João, Porto, Portugal.; WGO Gastroenterology and Hepatology Training Center, Porto, Portugal.; Department of Medicine, Faculty of Medicine of the University of Porto, Porto, Portugal.<br /><searchLink fieldCode="AU" term="%22Cardoso+P%22">Cardoso P</searchLink>; Gastroenterology Department, Centro Hospitalar Universitario de São João, Porto, Portugal.; WGO Gastroenterology and Hepatology Training Center, Porto, Portugal.; Department of Medicine, Faculty of Medicine of the University of Porto, Porto, Portugal.<br /><searchLink fieldCode="AU" term="%22Frias+J%22">Frias J</searchLink>; Gastroenterology Department, Centro Hospitalar Universitario de São João, Porto, Portugal.; WGO Gastroenterology and Hepatology Training Center, Porto, Portugal.; Department of Medicine, Faculty of Medicine of the University of Porto, Porto, Portugal.<br /><searchLink fieldCode="AU" term="%22Araújo+C%22">Araújo C</searchLink>; Gastroenterology Department, Centro Hospitalar Universitario de São João, Porto, Portugal.; WGO Gastroenterology and Hepatology Training Center, Porto, Portugal.; Department of Medicine, Faculty of Medicine of the University of Porto, Porto, Portugal.<br /><searchLink fieldCode="AU" term="%22Cardoso+H%22">Cardoso H</searchLink>; Gastroenterology Department, Centro Hospitalar Universitario de São João, Porto, Portugal.; WGO Gastroenterology and Hepatology Training Center, Porto, Portugal.; Department of Medicine, Faculty of Medicine of the University of Porto, Porto, Portugal.<br /><searchLink fieldCode="AU" term="%22Plaza+González+M%22">Plaza González M</searchLink>; 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Gastroenterology Deparment, Hospital Universitario Ramon y Cajal, Madrid, Spain.<br /><searchLink fieldCode="AU" term="%22Bicudo+de+Oliveira+L%22">Bicudo de Oliveira L</searchLink>; Digestive Endoscopy Department, Hospital das Clínicas da Faculdade de Medicina da Universidade de Sao Paulo, São Paulo, Brazil.<br /><searchLink fieldCode="AU" term="%22Ferreira+de+Carvalho+M%22">Ferreira de Carvalho M</searchLink>; Digestive Endoscopy Department, Hospital das Clínicas da Faculdade de Medicina da Universidade de Sao Paulo, São Paulo, Brazil.<br /><searchLink fieldCode="AU" term="%22Maluf-Filho+F%22">Maluf-Filho F</searchLink>; Digestive Endoscopy Department, Hospital das Clínicas da Faculdade de Medicina da Universidade de Sao Paulo, São Paulo, Brazil.; São Paulo State Cancer Institute, Universidade de Sao Paulo, São Paulo, Brazil.<br /><searchLink fieldCode="AU" term="%22Ferreira+MC%22">Ferreira MC</searchLink>; Gastrointestinal Endoscopy Department, Hospital Nove de Julho, São Paulo, Brazil.<br /><searchLink fieldCode="AU" term="%22Prince+T%22">Prince T</searchLink>; 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Gastroenterology Department, Centro Hospitalar Universitario de São João, Porto, Portugal.; WGO Gastroenterology and Hepatology Training Center, Porto, Portugal.; Department of Medicine, Faculty of Medicine of the University of Porto, Porto, Portugal.<br /><searchLink fieldCode="AU" term="%22Pereira+P%22">Pereira P</searchLink>; Gastroenterology Department, Centro Hospitalar Universitario de São João, Porto, Portugal.; WGO Gastroenterology and Hepatology Training Center, Porto, Portugal.; Department of Medicine, Faculty of Medicine of the University of Porto, Porto, Portugal.<br /><searchLink fieldCode="AU" term="%22Sabbagh+LC%22">Sabbagh LC</searchLink>; Gastrointestinal Endoscopy Department, Clínica Universitaria Colombia, Bogotá, Colombia.<br /><searchLink fieldCode="AU" term="%22Almuhaidb+A%22">Almuhaidb A</searchLink>; Department of Gastroenterology, King Faisal Specialist Hospital and Research Centre, Riyadh, Saudi Arabia.<br /><searchLink fieldCode="AU" term="%22Guimarães+Hourneaux+De+Moura+E%22">Guimarães Hourneaux De Moura E</searchLink>; Digestive Endoscopy Department, Hospital das Clínicas da Faculdade de Medicina da Universidade de Sao Paulo, São Paulo, Brazil.; Gastrointestinal Endoscopy Department, Hospital Vila Nova Star, São Paulo, Brazil .<br /><searchLink fieldCode="AU" term="%22Macedo+G%22">Macedo G</searchLink>; Gastroenterology Department, Centro Hospitalar Universitario de São João, Porto, Portugal.; WGO Gastroenterology and Hepatology Training Center, Porto, Portugal.; Department of Medicine, Faculty of Medicine of the University of Porto, Porto, Portugal.<br /><searchLink fieldCode="AU" term="%22González-Haba+M%22">González-Haba M</searchLink>; Gastroenterology Department, Hospital Universitario Puerta de Hierro Majadahonda, Madrid, Spain.
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