Graft-derived VWF drives platelet activation and thrombocytopenia during porcine liver xenotransplantation to brain-dead human recipients.
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| Title: | Graft-derived VWF drives platelet activation and thrombocytopenia during porcine liver xenotransplantation to brain-dead human recipients. |
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| Authors: | Zhao L; Department of Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA., Apostolidis SA; Department of Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA., Suzuki A; Department of Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA., Sarkar A; Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA., Guo Q; Division of Transplantation, Department of Surgery, New York University Langone Health, New York, New York, USA., Li F; Department of Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA., Sagar A; Nuffield Department of Surgical Sciences, University of Oxford, The Churchill Hospital, Oxford, United Kingdom., Fallon J; Nuffield Department of Surgical Sciences, University of Oxford, The Churchill Hospital, Oxford, United Kingdom., Elzawahry MA; Nuffield Department of Surgical Sciences, University of Oxford, The Churchill Hospital, Oxford, United Kingdom., Abbas SH; Nuffield Department of Surgical Sciences, University of Oxford, The Churchill Hospital, Oxford, United Kingdom., Lanieri L; eGenesis, Cambridge, Massachusetts, USA., Getchell K; eGenesis, Cambridge, Massachusetts, USA., Low SC; eGenesis, Cambridge, Massachusetts, USA., Olthoff KM; Penn Transplant Institute, Hospital of the University of Pennsylvania, Philadelphia, Pennsylvania, USA., Furth EE; Department of Pathology and Laboratory Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA., Keating BJ; Division of Transplantation, Department of Surgery, New York University Langone Health, New York, New York, USA., Friend P; Nuffield Department of Surgical Sciences, University of Oxford, The Churchill Hospital, Oxford, United Kingdom., Poncz M; Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA., Shaked A; Penn Transplant Institute, Hospital of the University of Pennsylvania, Philadelphia, Pennsylvania, USA., Abrams CS; Department of Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA. |
| Source: | The Journal of clinical investigation [J Clin Invest] 2026 Mar 10; Vol. 136 (9). Date of Electronic Publication: 2026 Mar 10 (Print Publication: 2026). |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: American Society for Clinical Investigation Country of Publication: United States NLM ID: 7802877 Publication Model: eCollection Cited Medium: Internet ISSN: 1558-8238 (Electronic) Linking ISSN: 00219738 NLM ISO Abbreviation: J Clin Invest Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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