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Optimization of pediatric dosing regimens for aztreonam and amoxicillin/clavulanate combination therapy against multidrug-resistant bacteria.

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Title: Optimization of pediatric dosing regimens for aztreonam and amoxicillin/clavulanate combination therapy against multidrug-resistant bacteria.
Authors: Wang L; Department of Pulmonary and Critical Care Medicine, Shandong Provincial Key Medical and Health Discipline, Qingdao Central Hospital, University of Health and Rehabilitation Sciences, Qingdao, 266042, China., Wu M; School of Medicine and Pharmacy, Ocean University of China, Qingdao, 266003, China., Qu L; Department of Pulmonary and Critical Care Medicine, Shandong Provincial Key Medical and Health Discipline, Qingdao Central Hospital, University of Health and Rehabilitation Sciences, Qingdao, 266042, China., Wang P; Department of Pulmonary and Critical Care Medicine, Shandong Provincial Key Medical and Health Discipline, Qingdao Central Hospital, University of Health and Rehabilitation Sciences, Qingdao, 266042, China., Yu Z; Department of Pulmonary and Critical Care Medicine, Shandong Provincial Key Medical and Health Discipline, Qingdao Central Hospital, University of Health and Rehabilitation Sciences, Qingdao, 266042, China., Deng H; Department of Pulmonary and Critical Care Medicine, Shandong Provincial Key Medical and Health Discipline, Qingdao Central Hospital, University of Health and Rehabilitation Sciences, Qingdao, 266042, China., Martins FS; Institute of Technology and Research, Aracaju, Sergipe, 49010-390, Brazil., Zhang J; School of Medicine and Pharmacy, Ocean University of China, Qingdao, 266003, China., Rong D; School of Medicine and Pharmacy, Ocean University of China, Qingdao, 266003, China., Yu M; School of Medicine and Pharmacy, Ocean University of China, Qingdao, 266003, China., Lv Z; School of Medicine and Pharmacy, Ocean University of China, Qingdao, 266003, China., Sy SKB; Department of Statistics, Universidade Estadual de Maringá, Maringá, 87020-900, Paraná, Brazil. sherwin.kenneth.sy@gmail.com., Wu X; Department of Pulmonary and Critical Care Medicine, Shandong Provincial Key Medical and Health Discipline, Qingdao Central Hospital, University of Health and Rehabilitation Sciences, Qingdao, 266042, China. Wuxiao990222@163.com.
Source: European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology [Eur J Clin Microbiol Infect Dis] 2026 Jun; Vol. 45 (6), pp. 1763-1783. Date of Electronic Publication: 2026 Mar 10.
Publication Type: Journal Article
Journal Info: Publisher: Springer Country of Publication: Germany NLM ID: 8804297 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1435-4373 (Electronic) Linking ISSN: 09349723 NLM ISO Abbreviation: Eur J Clin Microbiol Infect Dis Subsets: MEDLINE; In Process
Database: MEDLINE Ultimate
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  Data: Optimization of pediatric dosing regimens for aztreonam and amoxicillin/clavulanate combination therapy against multidrug-resistant bacteria.
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  Data: <searchLink fieldCode="AU" term="%22Wang+L%22">Wang L</searchLink>; Department of Pulmonary and Critical Care Medicine, Shandong Provincial Key Medical and Health Discipline, Qingdao Central Hospital, University of Health and Rehabilitation Sciences, Qingdao, 266042, China.<br /><searchLink fieldCode="AU" term="%22Wu+M%22">Wu M</searchLink>; School of Medicine and Pharmacy, Ocean University of China, Qingdao, 266003, China.<br /><searchLink fieldCode="AU" term="%22Qu+L%22">Qu L</searchLink>; Department of Pulmonary and Critical Care Medicine, Shandong Provincial Key Medical and Health Discipline, Qingdao Central Hospital, University of Health and Rehabilitation Sciences, Qingdao, 266042, China.<br /><searchLink fieldCode="AU" term="%22Wang+P%22">Wang P</searchLink>; Department of Pulmonary and Critical Care Medicine, Shandong Provincial Key Medical and Health Discipline, Qingdao Central Hospital, University of Health and Rehabilitation Sciences, Qingdao, 266042, China.<br /><searchLink fieldCode="AU" term="%22Yu+Z%22">Yu Z</searchLink>; Department of Pulmonary and Critical Care Medicine, Shandong Provincial Key Medical and Health Discipline, Qingdao Central Hospital, University of Health and Rehabilitation Sciences, Qingdao, 266042, China.<br /><searchLink fieldCode="AU" term="%22Deng+H%22">Deng H</searchLink>; Department of Pulmonary and Critical Care Medicine, Shandong Provincial Key Medical and Health Discipline, Qingdao Central Hospital, University of Health and Rehabilitation Sciences, Qingdao, 266042, China.<br /><searchLink fieldCode="AU" term="%22Martins+FS%22">Martins FS</searchLink>; Institute of Technology and Research, Aracaju, Sergipe, 49010-390, Brazil.<br /><searchLink fieldCode="AU" term="%22Zhang+J%22">Zhang J</searchLink>; School of Medicine and Pharmacy, Ocean University of China, Qingdao, 266003, China.<br /><searchLink fieldCode="AU" term="%22Rong+D%22">Rong D</searchLink>; School of Medicine and Pharmacy, Ocean University of China, Qingdao, 266003, China.<br /><searchLink fieldCode="AU" term="%22Yu+M%22">Yu M</searchLink>; School of Medicine and Pharmacy, Ocean University of China, Qingdao, 266003, China.<br /><searchLink fieldCode="AU" term="%22Lv+Z%22">Lv Z</searchLink>; School of Medicine and Pharmacy, Ocean University of China, Qingdao, 266003, China.<br /><searchLink fieldCode="AU" term="%22Sy+SKB%22">Sy SKB</searchLink>; Department of Statistics, Universidade Estadual de Maringá, Maringá, 87020-900, Paraná, Brazil. sherwin.kenneth.sy@gmail.com.<br /><searchLink fieldCode="AU" term="%22Wu+X%22">Wu X</searchLink>; Department of Pulmonary and Critical Care Medicine, Shandong Provincial Key Medical and Health Discipline, Qingdao Central Hospital, University of Health and Rehabilitation Sciences, Qingdao, 266042, China. Wuxiao990222@163.com.
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              Text: 2026 Jun
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