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Plasma GDF15 increases during hyperinsulinemic hypoglycemia in humans with post-bariatric hypoglycemia and after insulin exposure in mice.

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Title: Plasma GDF15 increases during hyperinsulinemic hypoglycemia in humans with post-bariatric hypoglycemia and after insulin exposure in mice.
Authors: Ferraz-Bannitz R; Research Division, Joslin Diabetes Center, Boston, MA, USA; Harvard Medical School, Boston, MA, USA., Pei L; Research Division, Joslin Diabetes Center, Boston, MA, USA; Harvard Medical School, Boston, MA, USA., Wang H; Research Division, Joslin Diabetes Center, Boston, MA, USA., Ozturk B; Research Division, Joslin Diabetes Center, Boston, MA, USA; Harvard Medical School, Boston, MA, USA., Casanova Querol P; Research Division, Joslin Diabetes Center, Boston, MA, USA; Harvard Medical School, Boston, MA, USA., Gonçalves da Cruz A; Research Division, Joslin Diabetes Center, Boston, MA, USA; Harvard Medical School, Boston, MA, USA., Cook TM; Section of Nutrition, Department of Pediatrics, Division of Endocrinology, Diabetes and Metabolism, University of Colorado Anschutz Medical Campus, Aurora, CO, USA., Saeed H; Research Division, Joslin Diabetes Center, Boston, MA, USA; Harvard Medical School, Boston, MA, USA., Osterwalder L; Research Division, Joslin Diabetes Center, Boston, MA, USA; Harvard Medical School, Boston, MA, USA., Poulos L; Research Division, Joslin Diabetes Center, Boston, MA, USA; Harvard Medical School, Boston, MA, USA., Saifeldin H; Research Division, Joslin Diabetes Center, Boston, MA, USA; Harvard Medical School, Boston, MA, USA., Cummings C; Research Division, Joslin Diabetes Center, Boston, MA, USA., Farahmandsadr M; Research Division, Joslin Diabetes Center, Boston, MA, USA; Harvard Medical School, Boston, MA, USA., Amore A; Research Division, Joslin Diabetes Center, Boston, MA, USA; Harvard Medical School, Boston, MA, USA., Sheehan A; Research Division, Joslin Diabetes Center, Boston, MA, USA; Harvard Medical School, Boston, MA, USA., Simonson DC; Harvard Medical School, Boston, MA, USA; Divsion of Endocrinology, Brigham and Women's Hospital, Boston, MA, USA., Sandoval DA; Section of Nutrition, Department of Pediatrics, Division of Endocrinology, Diabetes and Metabolism, University of Colorado Anschutz Medical Campus, Aurora, CO, USA., Patti ME; Research Division, Joslin Diabetes Center, Boston, MA, USA; Harvard Medical School, Boston, MA, USA. Electronic address: mary.elizabeth.patti@joslin.harvard.edu.
Source: Cell reports. Medicine [Cell Rep Med] 2026 Mar 17; Vol. 7 (3), pp. 102656. Date of Electronic Publication: 2026 Mar 09.
Publication Type: Journal Article
Journal Info: Publisher: Cell Press Country of Publication: United States NLM ID: 101766894 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2666-3791 (Electronic) Linking ISSN: 26663791 NLM ISO Abbreviation: Cell Rep Med Subsets: MEDLINE
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  Data: Plasma GDF15 increases during hyperinsulinemic hypoglycemia in humans with post-bariatric hypoglycemia and after insulin exposure in mice.
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  Data: <searchLink fieldCode="AU" term="%22Ferraz-Bannitz+R%22">Ferraz-Bannitz R</searchLink>; Research Division, Joslin Diabetes Center, Boston, MA, USA; Harvard Medical School, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Pei+L%22">Pei L</searchLink>; Research Division, Joslin Diabetes Center, Boston, MA, USA; Harvard Medical School, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Wang+H%22">Wang H</searchLink>; Research Division, Joslin Diabetes Center, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Ozturk+B%22">Ozturk B</searchLink>; Research Division, Joslin Diabetes Center, Boston, MA, USA; Harvard Medical School, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Casanova+Querol+P%22">Casanova Querol P</searchLink>; Research Division, Joslin Diabetes Center, Boston, MA, USA; Harvard Medical School, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Gonçalves+da+Cruz+A%22">Gonçalves da Cruz A</searchLink>; Research Division, Joslin Diabetes Center, Boston, MA, USA; Harvard Medical School, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Cook+TM%22">Cook TM</searchLink>; Section of Nutrition, Department of Pediatrics, Division of Endocrinology, Diabetes and Metabolism, University of Colorado Anschutz Medical Campus, Aurora, CO, USA.<br /><searchLink fieldCode="AU" term="%22Saeed+H%22">Saeed H</searchLink>; Research Division, Joslin Diabetes Center, Boston, MA, USA; Harvard Medical School, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Osterwalder+L%22">Osterwalder L</searchLink>; Research Division, Joslin Diabetes Center, Boston, MA, USA; Harvard Medical School, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Poulos+L%22">Poulos L</searchLink>; Research Division, Joslin Diabetes Center, Boston, MA, USA; Harvard Medical School, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Saifeldin+H%22">Saifeldin H</searchLink>; Research Division, Joslin Diabetes Center, Boston, MA, USA; Harvard Medical School, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Cummings+C%22">Cummings C</searchLink>; Research Division, Joslin Diabetes Center, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Farahmandsadr+M%22">Farahmandsadr M</searchLink>; Research Division, Joslin Diabetes Center, Boston, MA, USA; Harvard Medical School, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Amore+A%22">Amore A</searchLink>; Research Division, Joslin Diabetes Center, Boston, MA, USA; Harvard Medical School, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Sheehan+A%22">Sheehan A</searchLink>; Research Division, Joslin Diabetes Center, Boston, MA, USA; Harvard Medical School, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Simonson+DC%22">Simonson DC</searchLink>; Harvard Medical School, Boston, MA, USA; Divsion of Endocrinology, Brigham and Women's Hospital, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Sandoval+DA%22">Sandoval DA</searchLink>; Section of Nutrition, Department of Pediatrics, Division of Endocrinology, Diabetes and Metabolism, University of Colorado Anschutz Medical Campus, Aurora, CO, USA.<br /><searchLink fieldCode="AU" term="%22Patti+ME%22">Patti ME</searchLink>; Research Division, Joslin Diabetes Center, Boston, MA, USA; Harvard Medical School, Boston, MA, USA. Electronic address: mary.elizabeth.patti@joslin.harvard.edu.
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