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PAR2 deletion in the osteoblast lineage affords long-term cartilage protection in experimental osteoarthritis.

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Title: PAR2 deletion in the osteoblast lineage affords long-term cartilage protection in experimental osteoarthritis.
Authors: Huesa C; School of Infection & Immunity, University of Glasgow, Glasgow G12 8TA, UK. Electronic address: carmen.huesa@glasgow.ac.uk., McGrath S; School of Infection & Immunity, University of Glasgow, Glasgow G12 8TA, UK. Electronic address: sarah.mcgrath@med.uni-muenchen.de., Dunning L; Institute of Biomedical & Environmental Health Research, University of the West of Scotland, Paisley PA1 2BE, UK. Electronic address: lynettedunning25@gmail.com., Vieri ML; School of Infection & Immunity, University of Glasgow, Glasgow G12 8TA, UK. Electronic address: m.vieri@ucl.ac.uk., McCulloch K; Institute of Biomedical & Environmental Health Research, University of the West of Scotland, Paisley PA1 2BE, UK. Electronic address: kendal.mcculloch@gmail.com., McIntosh KA; Strathclyde Institute of Pharmacy and Biomedical Sciences, University of Strathclyde, Glasgow, UK. Electronic address: kathryn.a.mcintosh@strath.ac.uk., Brown T; Institute of Biomedical & Environmental Health Research, University of the West of Scotland, Paisley PA1 2BE, UK. Electronic address: tatianacap26@gmail.com., Cole JJ; School of Infection & Immunity, University of Glasgow, Glasgow G12 8TA, UK. Electronic address: john.cole@glasgow.ac.uk., Plevin R; Strathclyde Institute of Pharmacy and Biomedical Sciences, University of Strathclyde, Glasgow, UK. Electronic address: r.plevin@strath.ac.uk., Rowan AD; Biosciences Institute of Cellular Medicine, Newcastle University, Newcastle, UK. Electronic address: drew.rowan@newcastle.ac.uk., van 't Hof R; Institute of Life Course and Medical Sciences, University of Liverpool, Liverpool L7 8TX, UK; Vanthof scientific S.C., Ul. Kollataja 17A/2, Torun 87-100, Poland. Electronic address: rj.vanthof@gmail.com., Ferrell WR; School of Infection & Immunity, University of Glasgow, Glasgow G12 8TA, UK. Electronic address: william.ferrell@glasgow.ac.uk., Lockhart JC; Institute of Biomedical & Environmental Health Research, University of the West of Scotland, Paisley PA1 2BE, UK. Electronic address: john.lockhart@uws.ac.uk., Goodyear CS; School of Infection & Immunity, University of Glasgow, Glasgow G12 8TA, UK. Electronic address: carl.goodyear@glasgow.ac.uk.
Source: Osteoarthritis and cartilage [Osteoarthritis Cartilage] 2026 Jun; Vol. 34 (6), pp. 819-831. Date of Electronic Publication: 2026 Mar 08.
Publication Type: Journal Article
Journal Info: Publisher: W.B. Saunders For The Osteoarthritis Research Society Country of Publication: England NLM ID: 9305697 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1522-9653 (Electronic) Linking ISSN: 10634584 NLM ISO Abbreviation: Osteoarthritis Cartilage Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: PAR2 deletion in the osteoblast lineage affords long-term cartilage protection in experimental osteoarthritis.
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  Data: <searchLink fieldCode="AU" term="%22Huesa+C%22">Huesa C</searchLink>; School of Infection & Immunity, University of Glasgow, Glasgow G12 8TA, UK. Electronic address: carmen.huesa@glasgow.ac.uk.<br /><searchLink fieldCode="AU" term="%22McGrath+S%22">McGrath S</searchLink>; School of Infection & Immunity, University of Glasgow, Glasgow G12 8TA, UK. Electronic address: sarah.mcgrath@med.uni-muenchen.de.<br /><searchLink fieldCode="AU" term="%22Dunning+L%22">Dunning L</searchLink>; Institute of Biomedical & Environmental Health Research, University of the West of Scotland, Paisley PA1 2BE, UK. Electronic address: lynettedunning25@gmail.com.<br /><searchLink fieldCode="AU" term="%22Vieri+ML%22">Vieri ML</searchLink>; School of Infection & Immunity, University of Glasgow, Glasgow G12 8TA, UK. Electronic address: m.vieri@ucl.ac.uk.<br /><searchLink fieldCode="AU" term="%22McCulloch+K%22">McCulloch K</searchLink>; Institute of Biomedical & Environmental Health Research, University of the West of Scotland, Paisley PA1 2BE, UK. Electronic address: kendal.mcculloch@gmail.com.<br /><searchLink fieldCode="AU" term="%22McIntosh+KA%22">McIntosh KA</searchLink>; Strathclyde Institute of Pharmacy and Biomedical Sciences, University of Strathclyde, Glasgow, UK. Electronic address: kathryn.a.mcintosh@strath.ac.uk.<br /><searchLink fieldCode="AU" term="%22Brown+T%22">Brown T</searchLink>; Institute of Biomedical & Environmental Health Research, University of the West of Scotland, Paisley PA1 2BE, UK. Electronic address: tatianacap26@gmail.com.<br /><searchLink fieldCode="AU" term="%22Cole+JJ%22">Cole JJ</searchLink>; School of Infection & Immunity, University of Glasgow, Glasgow G12 8TA, UK. Electronic address: john.cole@glasgow.ac.uk.<br /><searchLink fieldCode="AU" term="%22Plevin+R%22">Plevin R</searchLink>; Strathclyde Institute of Pharmacy and Biomedical Sciences, University of Strathclyde, Glasgow, UK. Electronic address: r.plevin@strath.ac.uk.<br /><searchLink fieldCode="AU" term="%22Rowan+AD%22">Rowan AD</searchLink>; Biosciences Institute of Cellular Medicine, Newcastle University, Newcastle, UK. Electronic address: drew.rowan@newcastle.ac.uk.<br /><searchLink fieldCode="AU" term="%22van+'t+Hof+R%22">van 't Hof R</searchLink>; Institute of Life Course and Medical Sciences, University of Liverpool, Liverpool L7 8TX, UK; Vanthof scientific S.C., Ul. Kollataja 17A/2, Torun 87-100, Poland. Electronic address: rj.vanthof@gmail.com.<br /><searchLink fieldCode="AU" term="%22Ferrell+WR%22">Ferrell WR</searchLink>; School of Infection & Immunity, University of Glasgow, Glasgow G12 8TA, UK. Electronic address: william.ferrell@glasgow.ac.uk.<br /><searchLink fieldCode="AU" term="%22Lockhart+JC%22">Lockhart JC</searchLink>; Institute of Biomedical & Environmental Health Research, University of the West of Scotland, Paisley PA1 2BE, UK. Electronic address: john.lockhart@uws.ac.uk.<br /><searchLink fieldCode="AU" term="%22Goodyear+CS%22">Goodyear CS</searchLink>; School of Infection & Immunity, University of Glasgow, Glasgow G12 8TA, UK. Electronic address: carl.goodyear@glasgow.ac.uk.
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  Data: <searchLink fieldCode="JN" term="%229305697%22">Osteoarthritis and cartilage</searchLink> [Osteoarthritis Cartilage] 2026 Jun; Vol. 34 (6), pp. 819-831. <i>Date of Electronic Publication: </i>2026 Mar 08.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22W%2EB%2E+Saunders+For+The+Osteoarthritis+Research+Society%22">W.B. Saunders For The Osteoarthritis Research Society </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>9305697 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1522-9653 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2210634584%22">10634584 </searchLink><i>NLM ISO Abbreviation: </i>Osteoarthritis Cartilage <i>Subsets: </i>MEDLINE
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              Text: 2026 Jun
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