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Development and characterization of rat hindlimb ischemia models mimicking peripheral arterial disease severity.

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Title: Development and characterization of rat hindlimb ischemia models mimicking peripheral arterial disease severity.
Authors: Liang Y; Division of Plastic and Reconstructive Surgery, Department of Surgery, Washington University School of Medicine, St. Louis, MO, 63110, USA.; Plastic Surgery Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, China., Mullen C; Division of Plastic and Reconstructive Surgery, Department of Surgery, Washington University School of Medicine, St. Louis, MO, 63110, USA., Young ER; Division of Plastic and Reconstructive Surgery, Department of Surgery, Washington University School of Medicine, St. Louis, MO, 63110, USA., Zaghloul M; Section of Vascular Surgery, Department of Surgery, Washington University School of Medicine, St. Louis, MO, 63110, USA., Guo Y; Division of Plastic and Reconstructive Surgery, Department of Surgery, Washington University School of Medicine, St. Louis, MO, 63110, USA., Jin S; Division of Plastic and Reconstructive Surgery, Department of Surgery, Washington University School of Medicine, St. Louis, MO, 63110, USA., Yang M; Division of Plastic and Reconstructive Surgery, Department of Surgery, Washington University School of Medicine, St. Louis, MO, 63110, USA., Yan J; Division of Plastic and Reconstructive Surgery, Department of Surgery, Washington University School of Medicine, St. Louis, MO, 63110, USA., Xia X; Division of Plastic and Reconstructive Surgery, Department of Surgery, Washington University School of Medicine, St. Louis, MO, 63110, USA., Arif B; Section of Vascular Surgery, Department of Surgery, Washington University School of Medicine, St. Louis, MO, 63110, USA., Ly T; Division of Plastic and Reconstructive Surgery, Department of Surgery, Washington University School of Medicine, St. Louis, MO, 63110, USA., Li D; Division of Plastic and Reconstructive Surgery, Department of Surgery, Washington University School of Medicine, St. Louis, MO, 63110, USA., Lee T; Division of Plastic and Reconstructive Surgery, Department of Surgery, Washington University School of Medicine, St. Louis, MO, 63110, USA., Boukind A; Division of Plastic and Reconstructive Surgery, Department of Surgery, Washington University School of Medicine, St. Louis, MO, 63110, USA., Schofield JB; Division of Plastic and Reconstructive Surgery, Department of Surgery, Washington University School of Medicine, St. Louis, MO, 63110, USA., Zayed MA; Section of Vascular Surgery, Department of Surgery, Washington University School of Medicine, St. Louis, MO, 63110, USA.; Division of Molecular Cell Biology, Washington University School of Medicine, St. Louis, MO, 63110, USA.; Department of Biomedical Engineering, McKelvey School of Engineering, Washington University in St. Louis, St. Louis, MO, 63130, USA.; St. Louis Veterans Affairs Health Care System, St. Louis, MO, 63106, USA., Sacks JM; Division of Plastic and Reconstructive Surgery, Department of Surgery, Washington University School of Medicine, St. Louis, MO, 63110, USA., Li X; Division of Plastic and Reconstructive Surgery, Department of Surgery, Washington University School of Medicine, St. Louis, MO, 63110, USA. xiaoweili@wustl.edu.; Department of Biomedical Engineering, McKelvey School of Engineering, Washington University in St. Louis, St. Louis, MO, 63130, USA. xiaoweili@wustl.edu.
Source: Scientific reports [Sci Rep] 2026 Mar 10; Vol. 16 (1). Date of Electronic Publication: 2026 Mar 10.
Publication Type: Journal Article
Journal Info: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN: 2045-2322 (Electronic) Linking ISSN: 20452322 NLM ISO Abbreviation: Sci Rep Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Development and characterization of rat hindlimb ischemia models mimicking peripheral arterial disease severity.
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  Data: <searchLink fieldCode="AU" term="%22Liang+Y%22">Liang Y</searchLink>; Division of Plastic and Reconstructive Surgery, Department of Surgery, Washington University School of Medicine, St. Louis, MO, 63110, USA.; Plastic Surgery Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, China.<br /><searchLink fieldCode="AU" term="%22Mullen+C%22">Mullen C</searchLink>; Division of Plastic and Reconstructive Surgery, Department of Surgery, Washington University School of Medicine, St. Louis, MO, 63110, USA.<br /><searchLink fieldCode="AU" term="%22Young+ER%22">Young ER</searchLink>; Division of Plastic and Reconstructive Surgery, Department of Surgery, Washington University School of Medicine, St. Louis, MO, 63110, USA.<br /><searchLink fieldCode="AU" term="%22Zaghloul+M%22">Zaghloul M</searchLink>; Section of Vascular Surgery, Department of Surgery, Washington University School of Medicine, St. Louis, MO, 63110, USA.<br /><searchLink fieldCode="AU" term="%22Guo+Y%22">Guo Y</searchLink>; Division of Plastic and Reconstructive Surgery, Department of Surgery, Washington University School of Medicine, St. Louis, MO, 63110, USA.<br /><searchLink fieldCode="AU" term="%22Jin+S%22">Jin S</searchLink>; Division of Plastic and Reconstructive Surgery, Department of Surgery, Washington University School of Medicine, St. Louis, MO, 63110, USA.<br /><searchLink fieldCode="AU" term="%22Yang+M%22">Yang M</searchLink>; Division of Plastic and Reconstructive Surgery, Department of Surgery, Washington University School of Medicine, St. Louis, MO, 63110, USA.<br /><searchLink fieldCode="AU" term="%22Yan+J%22">Yan J</searchLink>; Division of Plastic and Reconstructive Surgery, Department of Surgery, Washington University School of Medicine, St. Louis, MO, 63110, USA.<br /><searchLink fieldCode="AU" term="%22Xia+X%22">Xia X</searchLink>; Division of Plastic and Reconstructive Surgery, Department of Surgery, Washington University School of Medicine, St. Louis, MO, 63110, USA.<br /><searchLink fieldCode="AU" term="%22Arif+B%22">Arif B</searchLink>; Section of Vascular Surgery, Department of Surgery, Washington University School of Medicine, St. Louis, MO, 63110, USA.<br /><searchLink fieldCode="AU" term="%22Ly+T%22">Ly T</searchLink>; Division of Plastic and Reconstructive Surgery, Department of Surgery, Washington University School of Medicine, St. Louis, MO, 63110, USA.<br /><searchLink fieldCode="AU" term="%22Li+D%22">Li D</searchLink>; Division of Plastic and Reconstructive Surgery, Department of Surgery, Washington University School of Medicine, St. Louis, MO, 63110, USA.<br /><searchLink fieldCode="AU" term="%22Lee+T%22">Lee T</searchLink>; Division of Plastic and Reconstructive Surgery, Department of Surgery, Washington University School of Medicine, St. Louis, MO, 63110, USA.<br /><searchLink fieldCode="AU" term="%22Boukind+A%22">Boukind A</searchLink>; Division of Plastic and Reconstructive Surgery, Department of Surgery, Washington University School of Medicine, St. Louis, MO, 63110, USA.<br /><searchLink fieldCode="AU" term="%22Schofield+JB%22">Schofield JB</searchLink>; Division of Plastic and Reconstructive Surgery, Department of Surgery, Washington University School of Medicine, St. Louis, MO, 63110, USA.<br /><searchLink fieldCode="AU" term="%22Zayed+MA%22">Zayed MA</searchLink>; Section of Vascular Surgery, Department of Surgery, Washington University School of Medicine, St. Louis, MO, 63110, USA.; Division of Molecular Cell Biology, Washington University School of Medicine, St. Louis, MO, 63110, USA.; Department of Biomedical Engineering, McKelvey School of Engineering, Washington University in St. Louis, St. Louis, MO, 63130, USA.; St. Louis Veterans Affairs Health Care System, St. Louis, MO, 63106, USA.<br /><searchLink fieldCode="AU" term="%22Sacks+JM%22">Sacks JM</searchLink>; Division of Plastic and Reconstructive Surgery, Department of Surgery, Washington University School of Medicine, St. Louis, MO, 63110, USA.<br /><searchLink fieldCode="AU" term="%22Li+X%22">Li X</searchLink>; Division of Plastic and Reconstructive Surgery, Department of Surgery, Washington University School of Medicine, St. Louis, MO, 63110, USA. xiaoweili@wustl.edu.; Department of Biomedical Engineering, McKelvey School of Engineering, Washington University in St. Louis, St. Louis, MO, 63130, USA. xiaoweili@wustl.edu.
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