Antiphospholipid antibodies and cardiovascular thrombosis.

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Title: Antiphospholipid antibodies and cardiovascular thrombosis.
Authors: Rashedi S; Division of Cardiovascular Medicine, Brigham and Women's Hospital and Heart and Vascular Institute, Mass General Brigham, Harvard Medical School, Boston, MA, USA.; Thrombosis Research Group, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA., Leyva H; Division of Cardiovascular Medicine, Brigham and Women's Hospital and Heart and Vascular Institute, Mass General Brigham, Harvard Medical School, Boston, MA, USA.; Thrombosis Research Group, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA., Siddiqui SA; Baim Institute for Clinical Research, Boston, MA, USA., Bukhari S; Division of Cardiology, Department of Medicine, Johns Hopkins University, Baltimore, MD, USA., Pfeferman MB; Division of Cardiovascular Medicine, Brigham and Women's Hospital and Heart and Vascular Institute, Mass General Brigham, Harvard Medical School, Boston, MA, USA.; Thrombosis Research Group, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA., Watson NW; Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA., Ujueta F; Division of Cardiovascular Medicine, Vanderbilt University Medical Center, Nashville, TN, USA., Zarghami M; Jamaica Hospital Medical Center, Queens, NY, USA., Bacare B; Division of Cardiovascular Medicine, Brigham and Women's Hospital and Heart and Vascular Institute, Mass General Brigham, Harvard Medical School, Boston, MA, USA.; Thrombosis Research Group, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA., Kanthi Y; Section of Vascular Thrombosis & Inflammation, Division of Intramural Research, National Heart, Lung and Blood Institute, Bethesda, MD, USA., Jimenez D; Respiratory Department, Hospital Ramón y Cajal and Instituto Ramón y Cajal de Investigación Sanitaria (IRYCIS), Madrid, Spain.; Medicine Department, Universidad de Alcalá, Campus Científico-Tecnológico, Alcalá de Henares, Madrid, Spain.; CIBER Enfermedades Respiratorias (CIBERES), Instituto de Salud Carlos III, Madrid, Spain., Monreal M; Cátedra de Enfermedad Tromboembólica, Universidad Católica San Antonio de Murcia, Murcia, Spain., Siegal DM; Division of Hematology, Department of Medicine and Ottawa Hospital Research Institute, University of Ottawa, Ottawa, Ontario, Canada.; Faculty of Medicine, University of Ottawa, Ottawa, Ontario, Canada., Barnes GD; Division of Cardiovascular Medicine, Frankel Cardiovascular Center, University of Michigan, Ann Arbor, MI, USA., Eikelboom JW; Department of Medicine, Population Health Research Institute, Faculty of Health Sciences, McMaster University, Hamilton, Ontario, Canada., O'Donoghue ML; TIMI Study Group, Division of Cardiovascular Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA., Ruff CT; TIMI Study Group, Division of Cardiovascular Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA., Galli M; Department of Medical-Surgical Sciences and Biotechnologies, Sapienza University of Rome, Latina, Italy.; Maria Cecilia Hospital, GVM Care & Research, Cotignola, Italy., Weber BN; Division of Cardiovascular Medicine, Brigham and Women's Hospital and Heart and Vascular Institute, Mass General Brigham, Harvard Medical School, Boston, MA, USA., Goldhaber SZ; Division of Cardiovascular Medicine, Brigham and Women's Hospital and Heart and Vascular Institute, Mass General Brigham, Harvard Medical School, Boston, MA, USA.; Thrombosis Research Group, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA., Uljon S; Department of Pathology, Massachusetts General Hospital, Mass General Brigham, Boston, MA, USA., Middeldorp S; Department of Internal Medicine, Radboud University Medical Center, Nijmegen, Netherlands., Lopes RD; Department of Cardiology, Duke University, Durham, NC, USA., Garcia DA; Division of Hematology, Department of Medicine, University of Washington, Seattle, WA, USA., Lip GYH; Liverpool Centre for Cardiovascular Science at University of Liverpool, Liverpool John Moores University and Liverpool Heart and Chest Hospital, Liverpool, UK.; Danish Center for Health Services Research, Department of Clinical Medicine, Aalborg University, Aalborg, Denmark., Weitz JI; Thrombosis and Atherosclerosis Research Institute, Hamilton Health Sciences, McMaster University, Hamilton, Ontario, Canada., Connors JM; Hematology Division, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA., Krumholz HM; YNHH/Yale Center for Outcomes Research and Evaluation (CORE), New Haven, CT, USA.; Section of Cardiovascular Medicine, Department of Internal Medicine, Yale School of Medicine, New Haven, CT, USA.; Department of Health Policy and Management, Yale School of Public Health, New Haven, CT, USA., Knight JS; Division of Rheumatology, Department of Internal Medicine, University of Michigan Medical School, Ann Arbor, MI, USA., Lippi G; Section of Clinical Biochemistry, University of Verona, Verona, Italy., Elkind MSV; Department of Neurology, Vagelos College of Physicians and Surgeons, Columbia University, New York, NY, USA.; Department of Epidemiology, Mailman School of Public Health, Columbia University, New York, NY, USA., Cushman M; Division of Hematology and Oncology, Department of Medicine, Larner College of Medicine at the University of Vermont, Burlington, VT, USA., Costenbader KH; Division of Rheumatology, Inflammation and Immunity, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA., Piazza G; Division of Cardiovascular Medicine, Brigham and Women's Hospital and Heart and Vascular Institute, Mass General Brigham, Harvard Medical School, Boston, MA, USA.; Thrombosis Research Group, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA., Bikdeli B; Division of Cardiovascular Medicine, Brigham and Women's Hospital and Heart and Vascular Institute, Mass General Brigham, Harvard Medical School, Boston, MA, USA. bbikdeli@bwh.harvard.edu.; Thrombosis Research Group, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA. bbikdeli@bwh.harvard.edu.; YNHH/Yale Center for Outcomes Research and Evaluation (CORE), New Haven, CT, USA. bbikdeli@bwh.harvard.edu.
Source: Nature reviews. Cardiology [Nat Rev Cardiol] 2026 Mar 10. Date of Electronic Publication: 2026 Mar 10.
Publication Type: Journal Article; Review
Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101500075 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1759-5010 (Electronic) Linking ISSN: 17595002 NLM ISO Abbreviation: Nat Rev Cardiol Subsets: MEDLINE
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Division of Hematology, Department of Medicine, University of Washington, Seattle, WA, USA.<br /><searchLink fieldCode="AU" term="%22Lip+GYH%22">Lip GYH</searchLink>; Liverpool Centre for Cardiovascular Science at University of Liverpool, Liverpool John Moores University and Liverpool Heart and Chest Hospital, Liverpool, UK.; Danish Center for Health Services Research, Department of Clinical Medicine, Aalborg University, Aalborg, Denmark.<br /><searchLink fieldCode="AU" term="%22Weitz+JI%22">Weitz JI</searchLink>; Thrombosis and Atherosclerosis Research Institute, Hamilton Health Sciences, McMaster University, Hamilton, Ontario, Canada.<br /><searchLink fieldCode="AU" term="%22Connors+JM%22">Connors JM</searchLink>; Hematology Division, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Krumholz+HM%22">Krumholz HM</searchLink>; YNHH/Yale Center for Outcomes Research and Evaluation (CORE), New Haven, CT, USA.; Section of Cardiovascular Medicine, Department of Internal Medicine, Yale School of Medicine, New Haven, CT, USA.; 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