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Cerebral oxygen extraction and blood flow in community-based older adults: associations with white matter hyperintensity and neurocognitive function.

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Title: Cerebral oxygen extraction and blood flow in community-based older adults: associations with white matter hyperintensity and neurocognitive function.
Authors: Yan Y; Department of Psychiatry, School of Public Health, The 2nd Affiliated Hospital of Zhejiang University School of Medicine, Hangzhou 310058, China.; Department of Brain-Computer Interface, Nanhu Brain-Computer Interface Institute, Hangzhou 311100, China.; The State Key Lab of Brain-Machine Intelligence, MOE Frontier Science Center for Brain Science and Brain-Machine Integration, Zhejiang University School of Medicine, Hangzhou 310058, China.; Key Laboratory of Intelligent Preventive Medicine of Zhejiang Province, Hangzhou, Zhejiang 310058, China., Zhao X; Department of Psychiatry, School of Public Health, The 2nd Affiliated Hospital of Zhejiang University School of Medicine, Hangzhou 310058, China.; Key Laboratory of Intelligent Preventive Medicine of Zhejiang Province, Hangzhou, Zhejiang 310058, China., Zhang Y; Department of Psychiatry, School of Public Health, The 2nd Affiliated Hospital of Zhejiang University School of Medicine, Hangzhou 310058, China.; Key Laboratory of Intelligent Preventive Medicine of Zhejiang Province, Hangzhou, Zhejiang 310058, China., Li W; Department of Psychiatry, School of Public Health, The 2nd Affiliated Hospital of Zhejiang University School of Medicine, Hangzhou 310058, China.; Key Laboratory of Intelligent Preventive Medicine of Zhejiang Province, Hangzhou, Zhejiang 310058, China., Lin Z; Department of Psychiatry, School of Public Health, The 2nd Affiliated Hospital of Zhejiang University School of Medicine, Hangzhou 310058, China.; Key Laboratory of Intelligent Preventive Medicine of Zhejiang Province, Hangzhou, Zhejiang 310058, China., Zhou Y; Department of Psychiatry, School of Public Health, The 2nd Affiliated Hospital of Zhejiang University School of Medicine, Hangzhou 310058, China.; Key Laboratory of Intelligent Preventive Medicine of Zhejiang Province, Hangzhou, Zhejiang 310058, China., Fang S; Department of Psychiatry, School of Public Health, The 2nd Affiliated Hospital of Zhejiang University School of Medicine, Hangzhou 310058, China.; Key Laboratory of Intelligent Preventive Medicine of Zhejiang Province, Hangzhou, Zhejiang 310058, China., Huang J; Department of Psychiatry, School of Public Health, The 2nd Affiliated Hospital of Zhejiang University School of Medicine, Hangzhou 310058, China.; Key Laboratory of Intelligent Preventive Medicine of Zhejiang Province, Hangzhou, Zhejiang 310058, China., Chen CL; Memory, Ageing, and Cognition Centre (MACC), Department of Pharmacology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore 119077, Singapore., Lin Z; Key Laboratory for Biomedical Engineering of Ministry of Education, Department of Biomedical Engineering, College of Biomedical Engineering & Instrument Science, Zhejiang University, Hangzhou, Zhejiang 310027, China., Xu X; Department of Psychiatry, School of Public Health, The 2nd Affiliated Hospital of Zhejiang University School of Medicine, Hangzhou 310058, China.; Department of Brain-Computer Interface, Nanhu Brain-Computer Interface Institute, Hangzhou 311100, China.; The State Key Lab of Brain-Machine Intelligence, MOE Frontier Science Center for Brain Science and Brain-Machine Integration, Zhejiang University School of Medicine, Hangzhou 310058, China.
Source: Brain communications [Brain Commun] 2026 Feb 24; Vol. 8 (2), pp. fcag056. Date of Electronic Publication: 2026 Feb 24 (Print Publication: 2026).
Publication Type: Journal Article
Journal Info: Publisher: Oxford University Press Country of Publication: England NLM ID: 101755125 Publication Model: eCollection Cited Medium: Internet ISSN: 2632-1297 (Electronic) Linking ISSN: 26321297 NLM ISO Abbreviation: Brain Commun Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
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  Data: <searchLink fieldCode="AU" term="%22Yan+Y%22">Yan Y</searchLink>; Department of Psychiatry, School of Public Health, The 2nd Affiliated Hospital of Zhejiang University School of Medicine, Hangzhou 310058, China.; Department of Brain-Computer Interface, Nanhu Brain-Computer Interface Institute, Hangzhou 311100, China.; The State Key Lab of Brain-Machine Intelligence, MOE Frontier Science Center for Brain Science and Brain-Machine Integration, Zhejiang University School of Medicine, Hangzhou 310058, China.; Key Laboratory of Intelligent Preventive Medicine of Zhejiang Province, Hangzhou, Zhejiang 310058, China.<br /><searchLink fieldCode="AU" term="%22Zhao+X%22">Zhao X</searchLink>; Department of Psychiatry, School of Public Health, The 2nd Affiliated Hospital of Zhejiang University School of Medicine, Hangzhou 310058, China.; Key Laboratory of Intelligent Preventive Medicine of Zhejiang Province, Hangzhou, Zhejiang 310058, China.<br /><searchLink fieldCode="AU" term="%22Zhang+Y%22">Zhang Y</searchLink>; Department of Psychiatry, School of Public Health, The 2nd Affiliated Hospital of Zhejiang University School of Medicine, Hangzhou 310058, China.; Key Laboratory of Intelligent Preventive Medicine of Zhejiang Province, Hangzhou, Zhejiang 310058, China.<br /><searchLink fieldCode="AU" term="%22Li+W%22">Li W</searchLink>; Department of Psychiatry, School of Public Health, The 2nd Affiliated Hospital of Zhejiang University School of Medicine, Hangzhou 310058, China.; Key Laboratory of Intelligent Preventive Medicine of Zhejiang Province, Hangzhou, Zhejiang 310058, China.<br /><searchLink fieldCode="AU" term="%22Lin+Z%22">Lin Z</searchLink>; Department of Psychiatry, School of Public Health, The 2nd Affiliated Hospital of Zhejiang University School of Medicine, Hangzhou 310058, China.; Key Laboratory of Intelligent Preventive Medicine of Zhejiang Province, Hangzhou, Zhejiang 310058, China.<br /><searchLink fieldCode="AU" term="%22Zhou+Y%22">Zhou Y</searchLink>; Department of Psychiatry, School of Public Health, The 2nd Affiliated Hospital of Zhejiang University School of Medicine, Hangzhou 310058, China.; Key Laboratory of Intelligent Preventive Medicine of Zhejiang Province, Hangzhou, Zhejiang 310058, China.<br /><searchLink fieldCode="AU" term="%22Fang+S%22">Fang S</searchLink>; Department of Psychiatry, School of Public Health, The 2nd Affiliated Hospital of Zhejiang University School of Medicine, Hangzhou 310058, China.; Key Laboratory of Intelligent Preventive Medicine of Zhejiang Province, Hangzhou, Zhejiang 310058, China.<br /><searchLink fieldCode="AU" term="%22Huang+J%22">Huang J</searchLink>; Department of Psychiatry, School of Public Health, The 2nd Affiliated Hospital of Zhejiang University School of Medicine, Hangzhou 310058, China.; Key Laboratory of Intelligent Preventive Medicine of Zhejiang Province, Hangzhou, Zhejiang 310058, China.<br /><searchLink fieldCode="AU" term="%22Chen+CL%22">Chen CL</searchLink>; Memory, Ageing, and Cognition Centre (MACC), Department of Pharmacology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore 119077, Singapore.<br /><searchLink fieldCode="AU" term="%22Lin+Z%22">Lin Z</searchLink>; Key Laboratory for Biomedical Engineering of Ministry of Education, Department of Biomedical Engineering, College of Biomedical Engineering & Instrument Science, Zhejiang University, Hangzhou, Zhejiang 310027, China.<br /><searchLink fieldCode="AU" term="%22Xu+X%22">Xu X</searchLink>; Department of Psychiatry, School of Public Health, The 2nd Affiliated Hospital of Zhejiang University School of Medicine, Hangzhou 310058, China.; Department of Brain-Computer Interface, Nanhu Brain-Computer Interface Institute, Hangzhou 311100, China.; The State Key Lab of Brain-Machine Intelligence, MOE Frontier Science Center for Brain Science and Brain-Machine Integration, Zhejiang University School of Medicine, Hangzhou 310058, China.
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        Value: 10.1093/braincomms/fcag056
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              Text: 2026 Feb 24
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