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Genetic risk loci for Parkinson's disease and dementia in a large-scale population-based Taiwanese cohort (TPMI).

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Title: Genetic risk loci for Parkinson's disease and dementia in a large-scale population-based Taiwanese cohort (TPMI).
Authors: Lin CH; Department of Neurology, National Taiwan University Hospital, Taipei, 100225, Taiwan.; School of Medicine, National Taiwan University, Taipei, 100225, Taiwan.; Graduate Institute of Biomedical Engineering, College of Medical Science and Technology, National Taiwan University, Taipei, 10617, Taiwan.; Graduate Institute of Molecular Medicine, College of Medicine, National Taiwan University, Taipei, 10617, Taiwan.; Graduate Institute of Brain and Mind Sciences, College of Medicine, National Taiwan University, Taipei, 10617, Taiwan., Chang CC; Institute of Biomedical Sciences, Academia Sinica, Taipei, 11529, Taiwan., Chen HH; Institute of Biomedical Sciences, Academia Sinica, Taipei, 11529, Taiwan., Lin WJ; Institute of Biomedical Sciences, Academia Sinica, Taipei, 11529, Taiwan., Hsu CL; Department of Medical Research, National Taiwan University Hospital, Taipei, 10025, Taiwan.; Graduate Institute of Oncology, National Taiwan University, Taipei, 10617, Taiwan.; Graduate Institute of Medical Genomics and Proteomics, National Taiwan University, Taipei, 10617, Taiwan.; Center for Computational and Systems Biology, National Taiwan University, Taipei, 10617, Taiwan., Lin RJ; Department of Neurology, National Taiwan University Hospital, Taipei, 100225, Taiwan., Guo YJ; Department of Neurological Institute, Taichung Veterans General Hospital, Taichung, 407005, Taiwan., Fang TC; Department of Neurological Institute, Taichung Veterans General Hospital, Taichung, 407005, Taiwan., Lin SZ; Bioinnovation Center, Buddhist Tzu Chi Medical Foundation, Hualien, 970473, Taiwan.; Department of Neurosurgery, Hualien Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, Hualien, 970473, Taiwan., Huang CY; Cardiovascular and Mitochondria Related Disease Research Center, Hualien Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, Hualien, 970473, Taiwan.; Department of Medical Research, China Medical University Hospital, China Medical University, Taichung, 406040, Taiwan.; Department of Biotechnology, Asia University, Taichung, 41354, Taiwan.; Center of General Education, Tzu Chi University, Hualien, 970374, Taiwan.; Graduate Institute of Biomedical Science, China Medical University, Taichung, 406040, Taiwan., Wang SJ; Department of Neurology, Neurological Institute, Taipei Veterans General Hospital, Taipei, 11217, Taiwan.; College of Medicine, National Yang Ming Chiao Tung University, Taipei, 112304, Taiwan.; Brain Research Center, National Yang Ming Chiao Tung University, Taipei, 112304, Taiwan., Hang JF; Department of Pathology and Laboratory Medicine, Taipei Veterans General Hospital, Taipei, 11217, Taiwan.; Department of Pathology, School of Medicine, National Yang Ming Chiao Tung University, Taipei, 112304, Taiwan., Hsieh SW; Department of Public Health, Kaohsiung Medical University, Kaohsiung, 807378, Taiwan.; Department of Neurology, Kaohsiung Municipal Siaogang Hospital, Kaohsiung Medical University, Kaohsiung, 807378, Taiwan.; Department of Neurology, Kaohsiung Medical University Hospital, Kaohsiung Medical University, Kaohsiung, 807378, Taiwan.; Department of Neurology, Faculty of Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung, 807378, Taiwan.; Neuroscience Research Center, Kaohsiung Medical University, Kaohsiung, 807378, Taiwan., Chou MC; Department of Neurology, Kaohsiung Medical University Hospital, Kaohsiung Medical University, Kaohsiung, 807378, Taiwan.; Neuroscience Research Center, Kaohsiung Medical University, Kaohsiung, 807378, Taiwan., Yeh TH; Department of Neurology, Taipei Medical University Hospital, Taipei, 110301, Taiwan.; Department of Neurology, College of Medicine, Taipei Medical University, Taipei, 110301, Taiwan., Hu CJ; Department of Neurology, College of Medicine, Taipei Medical University, Taipei, 110301, Taiwan.; Department of Neurology, Shuang-Ho Hospital, Taipei Medical University, New Taipei City, 23561, Taiwan., Yang FC; Department of Neurology, Tri-Service General Hospital, National Defense Medical Center, Taipei, 114202, Taiwan., Chang HA; Department of Psychiatry, Tri-Service General Hospital, National Defense Medical Center, Taipei, 114202, Taiwan., Lee TH; Department of Neurology, Chang Gung Memorial Hospital and College of Medicine, Chang Gung University, Taoyuan, 33302, Taiwan., Tsai MH; Department of Neurology, Kaohsiung Chang Gung Memorial Hospital, Kaohsiung, 83301, Taiwan.; School of Medicine, Chang Gung University, Taoyuan, 33302, Taiwan.; Doctoral Program of Clinical and Experimental Medicine, National Sun Yat-sen University, Kaohsiung, 80424, Taiwan., Kuo MC; Department of Medicine, National Taiwan University Cancer Center, Taipei, 11008, Taiwan., Liou JM; Department of Medicine, National Taiwan University Cancer Center, Taipei, 11008, Taiwan.; Department of Gastroenterology, National Taiwan University Hospital, College of Medicine, National Taiwan University, Taipei, 10025, Taiwan., Wu MS; Department of Gastroenterology, National Taiwan University Hospital, College of Medicine, National Taiwan University, Taipei, 10025, Taiwan., Park KW; Department of Neurology, Gangneung Asan Hospital University of Ulsan College of Medicine, Gangneung, South Korea., Chung SJ; Department of Neurology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, South Korea., Tan EK; Department of Neurology, Singapore General Hospital, Singapore, 169608, Singapore., Shen-Jang Fann C; Institute of Biomedical Sciences, Academia Sinica, Taipei, 11529, Taiwan.
Source: The Lancet regional health. Western Pacific [Lancet Reg Health West Pac] 2026 Mar 04; Vol. 68, pp. 101825. Date of Electronic Publication: 2026 Mar 04 (Print Publication: 2026).
Publication Type: Journal Article
Journal Info: Publisher: Elsevier Ltd Country of Publication: England NLM ID: 101774968 Publication Model: eCollection Cited Medium: Internet ISSN: 2666-6065 (Electronic) Linking ISSN: 26666065 NLM ISO Abbreviation: Lancet Reg Health West Pac Subsets: PubMed not MEDLINE
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  Data: Genetic risk loci for Parkinson's disease and dementia in a large-scale population-based Taiwanese cohort (TPMI).
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  Data: <searchLink fieldCode="AU" term="%22Lin+CH%22">Lin CH</searchLink>; Department of Neurology, National Taiwan University Hospital, Taipei, 100225, Taiwan.; School of Medicine, National Taiwan University, Taipei, 100225, Taiwan.; Graduate Institute of Biomedical Engineering, College of Medical Science and Technology, National Taiwan University, Taipei, 10617, Taiwan.; Graduate Institute of Molecular Medicine, College of Medicine, National Taiwan University, Taipei, 10617, Taiwan.; Graduate Institute of Brain and Mind Sciences, College of Medicine, National Taiwan University, Taipei, 10617, Taiwan.<br /><searchLink fieldCode="AU" term="%22Chang+CC%22">Chang CC</searchLink>; Institute of Biomedical Sciences, Academia Sinica, Taipei, 11529, Taiwan.<br /><searchLink fieldCode="AU" term="%22Chen+HH%22">Chen HH</searchLink>; Institute of Biomedical Sciences, Academia Sinica, Taipei, 11529, Taiwan.<br /><searchLink fieldCode="AU" term="%22Lin+WJ%22">Lin WJ</searchLink>; Institute of Biomedical Sciences, Academia Sinica, Taipei, 11529, Taiwan.<br /><searchLink fieldCode="AU" term="%22Hsu+CL%22">Hsu CL</searchLink>; Department of Medical Research, National Taiwan University Hospital, Taipei, 10025, Taiwan.; Graduate Institute of Oncology, National Taiwan University, Taipei, 10617, Taiwan.; Graduate Institute of Medical Genomics and Proteomics, National Taiwan University, Taipei, 10617, Taiwan.; Center for Computational and Systems Biology, National Taiwan University, Taipei, 10617, Taiwan.<br /><searchLink fieldCode="AU" term="%22Lin+RJ%22">Lin RJ</searchLink>; Department of Neurology, National Taiwan University Hospital, Taipei, 100225, Taiwan.<br /><searchLink fieldCode="AU" term="%22Guo+YJ%22">Guo YJ</searchLink>; Department of Neurological Institute, Taichung Veterans General Hospital, Taichung, 407005, Taiwan.<br /><searchLink fieldCode="AU" term="%22Fang+TC%22">Fang TC</searchLink>; Department of Neurological Institute, Taichung Veterans General Hospital, Taichung, 407005, Taiwan.<br /><searchLink fieldCode="AU" term="%22Lin+SZ%22">Lin SZ</searchLink>; Bioinnovation Center, Buddhist Tzu Chi Medical Foundation, Hualien, 970473, Taiwan.; Department of Neurosurgery, Hualien Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, Hualien, 970473, Taiwan.<br /><searchLink fieldCode="AU" term="%22Huang+CY%22">Huang CY</searchLink>; Cardiovascular and Mitochondria Related Disease Research Center, Hualien Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, Hualien, 970473, Taiwan.; Department of Medical Research, China Medical University Hospital, China Medical University, Taichung, 406040, Taiwan.; Department of Biotechnology, Asia University, Taichung, 41354, Taiwan.; Center of General Education, Tzu Chi University, Hualien, 970374, Taiwan.; Graduate Institute of Biomedical Science, China Medical University, Taichung, 406040, Taiwan.<br /><searchLink fieldCode="AU" term="%22Wang+SJ%22">Wang SJ</searchLink>; Department of Neurology, Neurological Institute, Taipei Veterans General Hospital, Taipei, 11217, Taiwan.; College of Medicine, National Yang Ming Chiao Tung University, Taipei, 112304, Taiwan.; Brain Research Center, National Yang Ming Chiao Tung University, Taipei, 112304, Taiwan.<br /><searchLink fieldCode="AU" term="%22Hang+JF%22">Hang JF</searchLink>; Department of Pathology and Laboratory Medicine, Taipei Veterans General Hospital, Taipei, 11217, Taiwan.; Department of Pathology, School of Medicine, National Yang Ming Chiao Tung University, Taipei, 112304, Taiwan.<br /><searchLink fieldCode="AU" term="%22Hsieh+SW%22">Hsieh SW</searchLink>; Department of Public Health, Kaohsiung Medical University, Kaohsiung, 807378, Taiwan.; Department of Neurology, Kaohsiung Municipal Siaogang Hospital, Kaohsiung Medical University, Kaohsiung, 807378, Taiwan.; Department of Neurology, Kaohsiung Medical University Hospital, Kaohsiung Medical University, Kaohsiung, 807378, Taiwan.; Department of Neurology, Faculty of Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung, 807378, Taiwan.; Neuroscience Research Center, Kaohsiung Medical University, Kaohsiung, 807378, Taiwan.<br /><searchLink fieldCode="AU" term="%22Chou+MC%22">Chou MC</searchLink>; Department of Neurology, Kaohsiung Medical University Hospital, Kaohsiung Medical University, Kaohsiung, 807378, Taiwan.; Neuroscience Research Center, Kaohsiung Medical University, Kaohsiung, 807378, Taiwan.<br /><searchLink fieldCode="AU" term="%22Yeh+TH%22">Yeh TH</searchLink>; Department of Neurology, Taipei Medical University Hospital, Taipei, 110301, Taiwan.; Department of Neurology, College of Medicine, Taipei Medical University, Taipei, 110301, Taiwan.<br /><searchLink fieldCode="AU" term="%22Hu+CJ%22">Hu CJ</searchLink>; Department of Neurology, College of Medicine, Taipei Medical University, Taipei, 110301, Taiwan.; Department of Neurology, Shuang-Ho Hospital, Taipei Medical University, New Taipei City, 23561, Taiwan.<br /><searchLink fieldCode="AU" term="%22Yang+FC%22">Yang FC</searchLink>; Department of Neurology, Tri-Service General Hospital, National Defense Medical Center, Taipei, 114202, Taiwan.<br /><searchLink fieldCode="AU" term="%22Chang+HA%22">Chang HA</searchLink>; Department of Psychiatry, Tri-Service General Hospital, National Defense Medical Center, Taipei, 114202, Taiwan.<br /><searchLink fieldCode="AU" term="%22Lee+TH%22">Lee TH</searchLink>; Department of Neurology, Chang Gung Memorial Hospital and College of Medicine, Chang Gung University, Taoyuan, 33302, Taiwan.<br /><searchLink fieldCode="AU" term="%22Tsai+MH%22">Tsai MH</searchLink>; Department of Neurology, Kaohsiung Chang Gung Memorial Hospital, Kaohsiung, 83301, Taiwan.; School of Medicine, Chang Gung University, Taoyuan, 33302, Taiwan.; Doctoral Program of Clinical and Experimental Medicine, National Sun Yat-sen University, Kaohsiung, 80424, Taiwan.<br /><searchLink fieldCode="AU" term="%22Kuo+MC%22">Kuo MC</searchLink>; Department of Medicine, National Taiwan University Cancer Center, Taipei, 11008, Taiwan.<br /><searchLink fieldCode="AU" term="%22Liou+JM%22">Liou JM</searchLink>; Department of Medicine, National Taiwan University Cancer Center, Taipei, 11008, Taiwan.; Department of Gastroenterology, National Taiwan University Hospital, College of Medicine, National Taiwan University, Taipei, 10025, Taiwan.<br /><searchLink fieldCode="AU" term="%22Wu+MS%22">Wu MS</searchLink>; Department of Gastroenterology, National Taiwan University Hospital, College of Medicine, National Taiwan University, Taipei, 10025, Taiwan.<br /><searchLink fieldCode="AU" term="%22Park+KW%22">Park KW</searchLink>; Department of Neurology, Gangneung Asan Hospital University of Ulsan College of Medicine, Gangneung, South Korea.<br /><searchLink fieldCode="AU" term="%22Chung+SJ%22">Chung SJ</searchLink>; Department of Neurology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, South Korea.<br /><searchLink fieldCode="AU" term="%22Tan+EK%22">Tan EK</searchLink>; Department of Neurology, Singapore General Hospital, Singapore, 169608, Singapore.<br /><searchLink fieldCode="AU" term="%22Shen-Jang+Fann+C%22">Shen-Jang Fann C</searchLink>; Institute of Biomedical Sciences, Academia Sinica, Taipei, 11529, Taiwan.
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  Data: <searchLink fieldCode="JN" term="%22101774968%22">The Lancet regional health. Western Pacific</searchLink> [Lancet Reg Health West Pac] 2026 Mar 04; Vol. 68, pp. 101825. <i>Date of Electronic Publication: </i>2026 Mar 04 (<i>Print Publication: </i>2026).
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Elsevier+Ltd%22">Elsevier Ltd </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>101774968 <i>Publication Model: </i>eCollection <i>Cited Medium: </i>Internet <i>ISSN: </i>2666-6065 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2226666065%22">26666065 </searchLink><i>NLM ISO Abbreviation: </i>Lancet Reg Health West Pac <i>Subsets: </i>PubMed not MEDLINE
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