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Prediction of incident heart failure in established atherosclerotic cardiovascular disease: the SMART2-HF model.

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Title: Prediction of incident heart failure in established atherosclerotic cardiovascular disease: the SMART2-HF model.
Authors: Reitsma TH; Department of Vascular Medicine and Endocrinology, University Medical Centre Utrecht, Utrecht, The Netherlands., Lim CE; Karolinska Institutet, Clinical Epidemiology Division, Department of Medicine, Stockholm, Sweden., Gynnild MN; Clinic of Cardiology, St. Olav University Hospital, Trondheim, Norway.; Department of Circulation and Medical Imaging, Faculty of Medicine and Health Science, NTNU - Norwegian University of Science and Technology, Trondheim, Norway.; K.G. Jebsen Center for Cardiac Biomarkers, Institute of Clinical Medicine, University of Oslo, Norway., Kaptoge S; British Heart Foundation Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Papworth Road, Cambridge Biomedical Campus, Cambridge, UK.; Victor Phillip Dahdaleh Heart and Lung Research Institute, University of Cambridge, Cambridge  UK., Lõo L; Institute of Family Medicine and Public Health, University of Tartu, Tartu, Estonia., Holtrop J; Department of Vascular Medicine and Endocrinology, University Medical Centre Utrecht, Utrecht, The Netherlands., Kuźma Ł; Medical University of Białystok, Department of Invasive Cardiology, Białystok, Poland.; National Medical Institute of the Ministry of Interior, Department of Cardiac Surgery and Transplantology, Warsaw, Poland.; Liverpool Centre for Cardiovascular Science, University of Liverpool, Liverpool, UK., Pennells L; British Heart Foundation Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Papworth Road, Cambridge Biomedical Campus, Cambridge, UK.; Victor Phillip Dahdaleh Heart and Lung Research Institute, University of Cambridge, Cambridge  UK.; British Heart Foundation Centre of Research Excellence, University of Cambridge, Cambridge, UK., Conrad N; Nuffield Department of Women's and Reproductive Health, University of Oxford, UK.; Department of Cardiovascular Sciences, Leuven, Belgium., Ueda P; Karolinska Institutet, Clinical Epidemiology Division, Department of Medicine, Stockholm, Sweden., Jernberg T; Department of Clinical Sciences, Cardiology, Karolinska Institutet Danderyd Hospital, Stockholm, Sweden., Kurasz A; Medical University of Białystok, Department of Invasive Cardiology, Białystok, Poland., Keene SJ; British Heart Foundation Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Papworth Road, Cambridge Biomedical Campus, Cambridge, UK.; Victor Phillip Dahdaleh Heart and Lung Research Institute, University of Cambridge, Cambridge  UK., Chilala C; British Heart Foundation Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Papworth Road, Cambridge Biomedical Campus, Cambridge, UK.; Victor Phillip Dahdaleh Heart and Lung Research Institute, University of Cambridge, Cambridge  UK., Deo SV; Surgical Services, Louis Stokes Cleveland VA Medical Center, Cleveland, OH, USA.; Case School of Medicine, Case Western Reserve University School of Medicine, Cleveland, OH, USA.; School of Health and Wellbeing, University of Glasgow, United Kingdom., Tillmann T; Institute of Family Medicine and Public Health, University of Tartu, Tartu, Estonia., Khunti K; Diabetes Research Centre, Leicester General Hospital, University of Leicester, Leicester, UK., Piepoli M; Department of Biomedical Science for Health, University of Milan, Italy.; Clinical University Cardiology, IRCCS Policlinico San Donato, Milan, Italy., Rossello X; Hospital Universitario Son Espases, Health Research Institute of the Balearic Islands, Universitat Illes Balears, Palma de Mallorca, Spain., Savarese G; Department of Clinical Science and Education, Södersjukhuset; Karolinska Institute, Stockholm, Sweden., Dalen H; Clinic of Cardiology, St. Olav University Hospital, Trondheim, Norway.; Department of Circulation and Medical Imaging, Faculty of Medicine and Health Science, NTNU - Norwegian University of Science and Technology, Trondheim, Norway.; Levanger Hospital, Nord-Trøndelag Hospital Trust, Levanger, Norway., Steg PG; Université Paris-Cité, FACT, French Alliance for Cardiovascular Trials, AP-HP; Hôpital Bichat; and INSERM U-1148, France., Wood AM; British Heart Foundation Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Papworth Road, Cambridge Biomedical Campus, Cambridge, UK.; Victor Phillip Dahdaleh Heart and Lung Research Institute, University of Cambridge, Cambridge  UK.; National Institute for Health and Care Research Blood and Transplant Research Unit in Donor Health and Behaviour, University of Cambridge, Cambridge, UK.; Health Data Research UK Cambridge, Wellcome Genome Campus and University of Cambridge, Cambridge, UK.; British Heart Foundation Data Science Centre, Health Data Research UK, London, UK., Lees JS; School of Cardiovascular & Metabolic Health, University of Glasgow, Glasgow, UK., Kavousi M; Department of Epidemiology, Erasmus MC, University Medical Centre Rotterdam, Rotterdam, The Netherlands., McEvoy JW; University of Galway School of Medicine and National Institute for Prevention and Cardiovascular Health, Galway, Ireland., de Boer RA; Cardiovascular Institute, Erasmus MC, Department of Cardiology, Thorax Center, Rotterdam, The Netherlands., Andersson C; Department of Cardiology, Copenhagen University Hospital Herlev and Gentofte, Herlev, Denmark.; Center for Advanced Heart Disease, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA., Bhatt DL; Mount Sinai Fuster Heart Hospital, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Visseren FLJ; Department of Vascular Medicine and Endocrinology, University Medical Centre Utrecht, Utrecht, The Netherlands., Dorresteijn JAN; Department of Vascular Medicine and Endocrinology, University Medical Centre Utrecht, Utrecht, The Netherlands., Koudstaal S; Cardiovascular Institute, Erasmus MC, Department of Cardiology, Thorax Center, Rotterdam, The Netherlands., Di Angelantonio E; British Heart Foundation Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Papworth Road, Cambridge Biomedical Campus, Cambridge, UK.; Victor Phillip Dahdaleh Heart and Lung Research Institute, University of Cambridge, Cambridge  UK.; British Heart Foundation Centre of Research Excellence, University of Cambridge, Cambridge, UK.; National Institute for Health and Care Research Blood and Transplant Research Unit in Donor Health and Behaviour, University of Cambridge, Cambridge, UK.; Health Data Research UK Cambridge, Wellcome Genome Campus and University of Cambridge, Cambridge, UK.; Health Data Science Research Centre, Human Technopole, Milan, Italy., Hageman SHJ; Department of Vascular Medicine and Endocrinology, University Medical Centre Utrecht, Utrecht, The Netherlands.
Corporate Authors: UCC-SMART study group, ESC Cardiovascular Risk Collaboration
Source: European heart journal [Eur Heart J] 2026 Mar 11. Date of Electronic Publication: 2026 Mar 11.
Publication Type: Journal Article
Journal Info: Publisher: Oxford University Press Country of Publication: England NLM ID: 8006263 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1522-9645 (Electronic) Linking ISSN: 0195668X NLM ISO Abbreviation: Eur Heart J Subsets: MEDLINE
Database: MEDLINE Ultimate
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Jebsen Center for Cardiac Biomarkers, Institute of Clinical Medicine, University of Oslo, Norway.<br /><searchLink fieldCode="AU" term="%22Kaptoge+S%22">Kaptoge S</searchLink>; British Heart Foundation Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Papworth Road, Cambridge Biomedical Campus, Cambridge, UK.; Victor Phillip Dahdaleh Heart and Lung Research Institute, University of Cambridge, Cambridge  UK.<br /><searchLink fieldCode="AU" term="%22Lõo+L%22">Lõo L</searchLink>; Institute of Family Medicine and Public Health, University of Tartu, Tartu, Estonia.<br /><searchLink fieldCode="AU" term="%22Holtrop+J%22">Holtrop J</searchLink>; Department of Vascular Medicine and Endocrinology, University Medical Centre Utrecht, Utrecht, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Kuźma+Ł%22">Kuźma Ł</searchLink>; Medical University of Białystok, Department of Invasive Cardiology, Białystok, Poland.; National Medical Institute of the Ministry of Interior, Department of Cardiac Surgery and Transplantology, Warsaw, Poland.; 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Department of Clinical Science and Education, Södersjukhuset; Karolinska Institute, Stockholm, Sweden.<br /><searchLink fieldCode="AU" term="%22Dalen+H%22">Dalen H</searchLink>; Clinic of Cardiology, St. Olav University Hospital, Trondheim, Norway.; Department of Circulation and Medical Imaging, Faculty of Medicine and Health Science, NTNU - Norwegian University of Science and Technology, Trondheim, Norway.; Levanger Hospital, Nord-Trøndelag Hospital Trust, Levanger, Norway.<br /><searchLink fieldCode="AU" term="%22Steg+PG%22">Steg PG</searchLink>; Université Paris-Cité, FACT, French Alliance for Cardiovascular Trials, AP-HP; Hôpital Bichat; and INSERM U-1148, France.<br /><searchLink fieldCode="AU" term="%22Wood+AM%22">Wood AM</searchLink>; British Heart Foundation Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Papworth Road, Cambridge Biomedical Campus, Cambridge, UK.; Victor Phillip Dahdaleh Heart and Lung Research Institute, University of Cambridge, Cambridge  UK.; National Institute for Health and Care Research Blood and Transplant Research Unit in Donor Health and Behaviour, University of Cambridge, Cambridge, UK.; Health Data Research UK Cambridge, Wellcome Genome Campus and University of Cambridge, Cambridge, UK.; British Heart Foundation Data Science Centre, Health Data Research UK, London, UK.<br /><searchLink fieldCode="AU" term="%22Lees+JS%22">Lees JS</searchLink>; School of Cardiovascular & Metabolic Health, University of Glasgow, Glasgow, UK.<br /><searchLink fieldCode="AU" term="%22Kavousi+M%22">Kavousi M</searchLink>; Department of Epidemiology, Erasmus MC, University Medical Centre Rotterdam, Rotterdam, The Netherlands.<br /><searchLink fieldCode="AU" term="%22McEvoy+JW%22">McEvoy JW</searchLink>; University of Galway School of Medicine and National Institute for Prevention and Cardiovascular Health, Galway, Ireland.<br /><searchLink fieldCode="AU" term="%22de+Boer+RA%22">de Boer RA</searchLink>; Cardiovascular Institute, Erasmus MC, Department of Cardiology, Thorax Center, Rotterdam, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Andersson+C%22">Andersson C</searchLink>; 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British Heart Foundation Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Papworth Road, Cambridge Biomedical Campus, Cambridge, UK.; Victor Phillip Dahdaleh Heart and Lung Research Institute, University of Cambridge, Cambridge  UK.; British Heart Foundation Centre of Research Excellence, University of Cambridge, Cambridge, UK.; National Institute for Health and Care Research Blood and Transplant Research Unit in Donor Health and Behaviour, University of Cambridge, Cambridge, UK.; Health Data Research UK Cambridge, Wellcome Genome Campus and University of Cambridge, Cambridge, UK.; Health Data Science Research Centre, Human Technopole, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Hageman+SHJ%22">Hageman SHJ</searchLink>; Department of Vascular Medicine and Endocrinology, University Medical Centre Utrecht, Utrecht, The Netherlands.
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