View in EDS HTML Full Text PDF Full Text

Exposure to high-altitude hypobaric hypoxic environment induces low-frequency hearing loss in C57BL/6J mice: Mediated by slowing down the postsynaptic electrical signal transmission speed in the cochlear-inferior colliculus auditory signaling pathway.

Saved in:
Bibliographic Details
Title: Exposure to high-altitude hypobaric hypoxic environment induces low-frequency hearing loss in C57BL/6J mice: Mediated by slowing down the postsynaptic electrical signal transmission speed in the cochlear-inferior colliculus auditory signaling pathway.
Authors: Ren B; Otolaryngology Department, Qinghai University Affiliated Hospital, Xining, Qinghai, China.; Otolaryngology Major, Clinical Medical College, Qinghai University, Xining, Qinghai, China.; Department of Otolaryngology-Head and Neck Surgery, Shanxi Fenyang Hospital, Lvliang, Shanxi, China., Zhang Q; Otolaryngology Department, Qinghai University Affiliated Hospital, Xining, Qinghai, China.; Otolaryngology Major, Clinical Medical College, Qinghai University, Xining, Qinghai, China., Gan W; Otolaryngology Department, Qinghai University Affiliated Hospital, Xining, Qinghai, China.; Otolaryngology Major, Clinical Medical College, Qinghai University, Xining, Qinghai, China., Yue G; Otolaryngology Department, Qinghai University Affiliated Hospital, Xining, Qinghai, China., Li S; Otolaryngology Department, Qinghai University Affiliated Hospital, Xining, Qinghai, China., Zhang X; Otolaryngology Department, Qinghai University Affiliated Hospital, Xining, Qinghai, China., Cao W; Otolaryngology Department, Qinghai University Affiliated Hospital, Xining, Qinghai, China., Tang F; Plateau Medical Research Center, Qinghai University, Xining, Qinghai, China., Zhang Y; Otolaryngology Department, Qinghai University Affiliated Hospital, Xining, Qinghai, China., Guo B; Otolaryngology Department, Qinghai University Affiliated Hospital, Xining, Qinghai, China., Wang Y; Otolaryngology Department, Qinghai University Affiliated Hospital, Xining, Qinghai, China.; Department of Otolaryngology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, China.
Source: PloS one [PLoS One] 2026 Mar 11; Vol. 21 (3), pp. e0342321. Date of Electronic Publication: 2026 Mar 11 (Print Publication: 2026).
Publication Type: Journal Article
Journal Info: Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet ISSN: 1932-6203 (Electronic) Linking ISSN: 19326203 NLM ISO Abbreviation: PLoS One Subsets: MEDLINE
Database: MEDLINE Ultimate
Full text is not displayed to guests.
FullText Links:
  – Type: pdflink
Text:
  Availability: 1
Header DbId: mdl
DbLabel: MEDLINE Ultimate
An: 41811883
AccessLevel: 2
PubType: Academic Journal
PubTypeId: academicJournal
PreciseRelevancyScore: 0
IllustrationInfo
Items – Name: Title
  Label: Title
  Group: Ti
  Data: Exposure to high-altitude hypobaric hypoxic environment induces low-frequency hearing loss in C57BL/6J mice: Mediated by slowing down the postsynaptic electrical signal transmission speed in the cochlear-inferior colliculus auditory signaling pathway.
– Name: Author
  Label: Authors
  Group: Au
  Data: <searchLink fieldCode="AU" term="%22Ren+B%22">Ren B</searchLink>; Otolaryngology Department, Qinghai University Affiliated Hospital, Xining, Qinghai, China.; Otolaryngology Major, Clinical Medical College, Qinghai University, Xining, Qinghai, China.; Department of Otolaryngology-Head and Neck Surgery, Shanxi Fenyang Hospital, Lvliang, Shanxi, China.<br /><searchLink fieldCode="AU" term="%22Zhang+Q%22">Zhang Q</searchLink>; Otolaryngology Department, Qinghai University Affiliated Hospital, Xining, Qinghai, China.; Otolaryngology Major, Clinical Medical College, Qinghai University, Xining, Qinghai, China.<br /><searchLink fieldCode="AU" term="%22Gan+W%22">Gan W</searchLink>; Otolaryngology Department, Qinghai University Affiliated Hospital, Xining, Qinghai, China.; Otolaryngology Major, Clinical Medical College, Qinghai University, Xining, Qinghai, China.<br /><searchLink fieldCode="AU" term="%22Yue+G%22">Yue G</searchLink>; Otolaryngology Department, Qinghai University Affiliated Hospital, Xining, Qinghai, China.<br /><searchLink fieldCode="AU" term="%22Li+S%22">Li S</searchLink>; Otolaryngology Department, Qinghai University Affiliated Hospital, Xining, Qinghai, China.<br /><searchLink fieldCode="AU" term="%22Zhang+X%22">Zhang X</searchLink>; Otolaryngology Department, Qinghai University Affiliated Hospital, Xining, Qinghai, China.<br /><searchLink fieldCode="AU" term="%22Cao+W%22">Cao W</searchLink>; Otolaryngology Department, Qinghai University Affiliated Hospital, Xining, Qinghai, China.<br /><searchLink fieldCode="AU" term="%22Tang+F%22">Tang F</searchLink>; Plateau Medical Research Center, Qinghai University, Xining, Qinghai, China.<br /><searchLink fieldCode="AU" term="%22Zhang+Y%22">Zhang Y</searchLink>; Otolaryngology Department, Qinghai University Affiliated Hospital, Xining, Qinghai, China.<br /><searchLink fieldCode="AU" term="%22Guo+B%22">Guo B</searchLink>; Otolaryngology Department, Qinghai University Affiliated Hospital, Xining, Qinghai, China.<br /><searchLink fieldCode="AU" term="%22Wang+Y%22">Wang Y</searchLink>; Otolaryngology Department, Qinghai University Affiliated Hospital, Xining, Qinghai, China.; Department of Otolaryngology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, China.
– Name: TitleSource
  Label: Source
  Group: Src
  Data: <searchLink fieldCode="JN" term="%22101285081%22">PloS one</searchLink> [PLoS One] 2026 Mar 11; Vol. 21 (3), pp. e0342321. <i>Date of Electronic Publication: </i>2026 Mar 11 (<i>Print Publication: </i>2026).
– Name: TypePub
  Label: Publication Type
  Group: TypPub
  Data: Journal Article
– Name: TitleSource
  Label: Journal Info
  Group: Src
  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Public+Library+of+Science%22">Public Library of Science </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>101285081 <i>Publication Model: </i>eCollection <i>Cited Medium: </i>Internet <i>ISSN: </i>1932-6203 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2219326203%22">19326203 </searchLink><i>NLM ISO Abbreviation: </i>PLoS One <i>Subsets: </i>MEDLINE
PLink https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=41811883
RecordInfo BibRecord:
  BibEntity:
    Identifiers:
      – Type: doi
        Value: 10.1371/journal.pone.0342321
    Languages:
      – Code: eng
        Text: English
    PhysicalDescription:
      Pagination:
        StartPage: e0342321
    Titles:
      – TitleFull: Exposure to high-altitude hypobaric hypoxic environment induces low-frequency hearing loss in C57BL/6J mice: Mediated by slowing down the postsynaptic electrical signal transmission speed in the cochlear-inferior colliculus auditory signaling pathway.
        Type: main
  BibRelationships:
    HasContributorRelationships:
      – PersonEntity:
          Name:
            NameFull: Ren B
      – PersonEntity:
          Name:
            NameFull: Zhang Q
      – PersonEntity:
          Name:
            NameFull: Gan W
      – PersonEntity:
          Name:
            NameFull: Yue G
      – PersonEntity:
          Name:
            NameFull: Li S
      – PersonEntity:
          Name:
            NameFull: Zhang X
      – PersonEntity:
          Name:
            NameFull: Cao W
      – PersonEntity:
          Name:
            NameFull: Tang F
      – PersonEntity:
          Name:
            NameFull: Zhang Y
      – PersonEntity:
          Name:
            NameFull: Guo B
      – PersonEntity:
          Name:
            NameFull: Wang Y
    IsPartOfRelationships:
      – BibEntity:
          Dates:
            – D: 11
              M: 03
              Text: 2026 Mar 11
              Type: published
              Y: 2026
          Identifiers:
            – Type: issn-electronic
              Value: 1932-6203
          Numbering:
            – Type: volume
              Value: 21
            – Type: issue
              Value: 3
          Titles:
            – TitleFull: PloS one
              Type: main
ResultId 1