Dual-positive CTCs in patients with advanced breast cancer show metastatic potential and prognostic value.

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Title: Dual-positive CTCs in patients with advanced breast cancer show metastatic potential and prognostic value.
Authors: Reduzzi C; Department of Medicine, Division of Hematology-Oncology, Weill Cornell Medicine, New York, NY 10021, USA., Nicolò E; Department of Medicine, Division of Hematology-Oncology, Weill Cornell Medicine, New York, NY 10021, USA., Gerratana L; Department of Medicine, University of Udine, Udine 33100, Italy.; Department of Medical Oncology, CRO Aviano, National Cancer Institute, IRCCS, Aviano 33081, Italy., Ozimski LL; Department of Biology, Institute of Molecular Health Sciences, Swiss Federal Institute of Technology (ETH) Zurich, Zurich 8049, Switzerland., Silvestri M; Department of Advanced Diagnostics, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan 20133, Italy., Zhang Y; Department of Medicine, Division of Hematology and Oncology, Northwestern University Feinberg School of Medicine, Chicago, IL 60611, USA., Scholten D; Department of Medicine, Division of Hematology and Oncology, Northwestern University Feinberg School of Medicine, Chicago, IL 60611, USA., Serafini MS; Department of Medicine, Division of Hematology-Oncology, Weill Cornell Medicine, New York, NY 10021, USA., Manai M; Department of Medicine, Division of Hematology and Oncology, Northwestern University Feinberg School of Medicine, Chicago, IL 60611, USA.; Pasteur Institute of Tunis, University of Tunis El Manar, Tunis 1002, Tunisia., D'Amico P; Department of Medicine, Division of Hematology and Oncology, Northwestern University Feinberg School of Medicine, Chicago, IL 60611, USA., Molteni E; Department of Medicine, Division of Hematology-Oncology, Weill Cornell Medicine, New York, NY 10021, USA.; Department of Medicine, University of Udine, Udine 33100, Italy., Bayou N; Department of Medicine, Division of Hematology-Oncology, Weill Cornell Medicine, New York, NY 10021, USA., Pastò B; Department of Medicine, Division of Hematology-Oncology, Weill Cornell Medicine, New York, NY 10021, USA.; Department of Medicine, University of Udine, Udine 33100, Italy., Saini M; Department of Biology, Institute of Molecular Health Sciences, Swiss Federal Institute of Technology (ETH) Zurich, Zurich 8049, Switzerland., Davis AA; Washington University in St. Louis School of Medicine, St. Louis, MO 63110, USA., Di Cosimo S; Department of Advanced Diagnostics, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan 20133, Italy., Cappelletti V; Department of Advanced Diagnostics, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan 20133, Italy., Liu H; Department of Medicine, Division of Hematology and Oncology, Northwestern University Feinberg School of Medicine, Chicago, IL 60611, USA.; Department of Pharmacology, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611, USA.; Chan Zuckerberg Biohub Chicago, Chicago, IL 60642, USA., Gradishar WJ; Department of Medicine, Division of Hematology and Oncology, Northwestern University Feinberg School of Medicine, Chicago, IL 60611, USA., Aceto N; Department of Biology, Institute of Molecular Health Sciences, Swiss Federal Institute of Technology (ETH) Zurich, Zurich 8049, Switzerland., Cristofanilli M; Department of Medicine, Division of Hematology-Oncology, Weill Cornell Medicine, New York, NY 10021, USA.
Source: Science translational medicine [Sci Transl Med] 2026 Mar 11; Vol. 18 (840), pp. eadw7698. Date of Electronic Publication: 2026 Mar 11.
Publication Type: Journal Article
Journal Info: Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 101505086 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1946-6242 (Electronic) Linking ISSN: 19466234 NLM ISO Abbreviation: Sci Transl Med Subsets: MEDLINE
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  Data: Dual-positive CTCs in patients with advanced breast cancer show metastatic potential and prognostic value.
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  Data: <searchLink fieldCode="AU" term="%22Reduzzi+C%22">Reduzzi C</searchLink>; Department of Medicine, Division of Hematology-Oncology, Weill Cornell Medicine, New York, NY 10021, USA.<br /><searchLink fieldCode="AU" term="%22Nicolò+E%22">Nicolò E</searchLink>; Department of Medicine, Division of Hematology-Oncology, Weill Cornell Medicine, New York, NY 10021, USA.<br /><searchLink fieldCode="AU" term="%22Gerratana+L%22">Gerratana L</searchLink>; Department of Medicine, University of Udine, Udine 33100, Italy.; Department of Medical Oncology, CRO Aviano, National Cancer Institute, IRCCS, Aviano 33081, Italy.<br /><searchLink fieldCode="AU" term="%22Ozimski+LL%22">Ozimski LL</searchLink>; Department of Biology, Institute of Molecular Health Sciences, Swiss Federal Institute of Technology (ETH) Zurich, Zurich 8049, Switzerland.<br /><searchLink fieldCode="AU" term="%22Silvestri+M%22">Silvestri M</searchLink>; Department of Advanced Diagnostics, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan 20133, Italy.<br /><searchLink fieldCode="AU" term="%22Zhang+Y%22">Zhang Y</searchLink>; Department of Medicine, Division of Hematology and Oncology, Northwestern University Feinberg School of Medicine, Chicago, IL 60611, USA.<br /><searchLink fieldCode="AU" term="%22Scholten+D%22">Scholten D</searchLink>; Department of Medicine, Division of Hematology and Oncology, Northwestern University Feinberg School of Medicine, Chicago, IL 60611, USA.<br /><searchLink fieldCode="AU" term="%22Serafini+MS%22">Serafini MS</searchLink>; Department of Medicine, Division of Hematology-Oncology, Weill Cornell Medicine, New York, NY 10021, USA.<br /><searchLink fieldCode="AU" term="%22Manai+M%22">Manai M</searchLink>; Department of Medicine, Division of Hematology and Oncology, Northwestern University Feinberg School of Medicine, Chicago, IL 60611, USA.; Pasteur Institute of Tunis, University of Tunis El Manar, Tunis 1002, Tunisia.<br /><searchLink fieldCode="AU" term="%22D'Amico+P%22">D'Amico P</searchLink>; Department of Medicine, Division of Hematology and Oncology, Northwestern University Feinberg School of Medicine, Chicago, IL 60611, USA.<br /><searchLink fieldCode="AU" term="%22Molteni+E%22">Molteni E</searchLink>; Department of Medicine, Division of Hematology-Oncology, Weill Cornell Medicine, New York, NY 10021, USA.; Department of Medicine, University of Udine, Udine 33100, Italy.<br /><searchLink fieldCode="AU" term="%22Bayou+N%22">Bayou N</searchLink>; Department of Medicine, Division of Hematology-Oncology, Weill Cornell Medicine, New York, NY 10021, USA.<br /><searchLink fieldCode="AU" term="%22Pastò+B%22">Pastò B</searchLink>; Department of Medicine, Division of Hematology-Oncology, Weill Cornell Medicine, New York, NY 10021, USA.; Department of Medicine, University of Udine, Udine 33100, Italy.<br /><searchLink fieldCode="AU" term="%22Saini+M%22">Saini M</searchLink>; Department of Biology, Institute of Molecular Health Sciences, Swiss Federal Institute of Technology (ETH) Zurich, Zurich 8049, Switzerland.<br /><searchLink fieldCode="AU" term="%22Davis+AA%22">Davis AA</searchLink>; Washington University in St. Louis School of Medicine, St. Louis, MO 63110, USA.<br /><searchLink fieldCode="AU" term="%22Di+Cosimo+S%22">Di Cosimo S</searchLink>; Department of Advanced Diagnostics, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan 20133, Italy.<br /><searchLink fieldCode="AU" term="%22Cappelletti+V%22">Cappelletti V</searchLink>; Department of Advanced Diagnostics, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan 20133, Italy.<br /><searchLink fieldCode="AU" term="%22Liu+H%22">Liu H</searchLink>; Department of Medicine, Division of Hematology and Oncology, Northwestern University Feinberg School of Medicine, Chicago, IL 60611, USA.; Department of Pharmacology, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611, USA.; Chan Zuckerberg Biohub Chicago, Chicago, IL 60642, USA.<br /><searchLink fieldCode="AU" term="%22Gradishar+WJ%22">Gradishar WJ</searchLink>; Department of Medicine, Division of Hematology and Oncology, Northwestern University Feinberg School of Medicine, Chicago, IL 60611, USA.<br /><searchLink fieldCode="AU" term="%22Aceto+N%22">Aceto N</searchLink>; Department of Biology, Institute of Molecular Health Sciences, Swiss Federal Institute of Technology (ETH) Zurich, Zurich 8049, Switzerland.<br /><searchLink fieldCode="AU" term="%22Cristofanilli+M%22">Cristofanilli M</searchLink>; Department of Medicine, Division of Hematology-Oncology, Weill Cornell Medicine, New York, NY 10021, USA.
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  Data: <searchLink fieldCode="JN" term="%22101505086%22">Science translational medicine</searchLink> [Sci Transl Med] 2026 Mar 11; Vol. 18 (840), pp. eadw7698. <i>Date of Electronic Publication: </i>2026 Mar 11.
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