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WEE1 stabilizes MYC to promote therapeutic resistance in esophageal adenocarcinoma.

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Title: WEE1 stabilizes MYC to promote therapeutic resistance in esophageal adenocarcinoma.
Authors: Thangaretnam K; Department of Surgery, Sylvester Comprehensive Cancer Center, University of Miami, Miami, FL, USA., Islam MO; Department of Surgery, Sylvester Comprehensive Cancer Center, University of Miami, Miami, FL, USA., Lv J; Department of Surgery, Sylvester Comprehensive Cancer Center, University of Miami, Miami, FL, USA., Zhang Z; Department of Surgery, Sylvester Comprehensive Cancer Center, University of Miami, Miami, FL, USA., Chen L; Department of Surgery, Sylvester Comprehensive Cancer Center, University of Miami, Miami, FL, USA., Ballout F; Department of Surgery, Sylvester Comprehensive Cancer Center, University of Miami, Miami, FL, USA., Lu H; Department of Surgery, Sylvester Comprehensive Cancer Center, University of Miami, Miami, FL, USA., Peng D; Department of Surgery, Sylvester Comprehensive Cancer Center, University of Miami, Miami, FL, USA., Zaika A; Department of Surgery, Sylvester Comprehensive Cancer Center, University of Miami, Miami, FL, USA., El-Rifai W; Department of Surgery, Sylvester Comprehensive Cancer Center, University of Miami, Miami, FL, USA; Department of Veterans Affairs, Miami Healthcare System, Miami, FL, USA., Giordano S; University of Torino, Candiolo Cancer Institute - FPO, IRCCS, Candiolo, Italy., Ban Y; Department of Public Health Sciences, Miller School of Medicine, University of Miami, Miami, FL, 33136, USA., Bilbao D; Sylvester Comprehensive Cancer Center, Miami, FL, USA; Department of Pathology, Miller School of Medicine, University of Miami, USA., Chen Z; Department of Surgery, Sylvester Comprehensive Cancer Center, University of Miami, Miami, FL, USA. Electronic address: zheng.chen@med.miami.edu.
Source: Cancer letters [Cancer Lett] 2026 May 28; Vol. 646, pp. 218418. Date of Electronic Publication: 2026 Mar 10.
Publication Type: Journal Article
Journal Info: Publisher: Elsevier Science Ireland Country of Publication: Ireland NLM ID: 7600053 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1872-7980 (Electronic) Linking ISSN: 03043835 NLM ISO Abbreviation: Cancer Lett Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: WEE1 stabilizes MYC to promote therapeutic resistance in esophageal adenocarcinoma.
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  Data: <searchLink fieldCode="AU" term="%22Thangaretnam+K%22">Thangaretnam K</searchLink>; Department of Surgery, Sylvester Comprehensive Cancer Center, University of Miami, Miami, FL, USA.<br /><searchLink fieldCode="AU" term="%22Islam+MO%22">Islam MO</searchLink>; Department of Surgery, Sylvester Comprehensive Cancer Center, University of Miami, Miami, FL, USA.<br /><searchLink fieldCode="AU" term="%22Lv+J%22">Lv J</searchLink>; Department of Surgery, Sylvester Comprehensive Cancer Center, University of Miami, Miami, FL, USA.<br /><searchLink fieldCode="AU" term="%22Zhang+Z%22">Zhang Z</searchLink>; Department of Surgery, Sylvester Comprehensive Cancer Center, University of Miami, Miami, FL, USA.<br /><searchLink fieldCode="AU" term="%22Chen+L%22">Chen L</searchLink>; Department of Surgery, Sylvester Comprehensive Cancer Center, University of Miami, Miami, FL, USA.<br /><searchLink fieldCode="AU" term="%22Ballout+F%22">Ballout F</searchLink>; Department of Surgery, Sylvester Comprehensive Cancer Center, University of Miami, Miami, FL, USA.<br /><searchLink fieldCode="AU" term="%22Lu+H%22">Lu H</searchLink>; Department of Surgery, Sylvester Comprehensive Cancer Center, University of Miami, Miami, FL, USA.<br /><searchLink fieldCode="AU" term="%22Peng+D%22">Peng D</searchLink>; Department of Surgery, Sylvester Comprehensive Cancer Center, University of Miami, Miami, FL, USA.<br /><searchLink fieldCode="AU" term="%22Zaika+A%22">Zaika A</searchLink>; Department of Surgery, Sylvester Comprehensive Cancer Center, University of Miami, Miami, FL, USA.<br /><searchLink fieldCode="AU" term="%22El-Rifai+W%22">El-Rifai W</searchLink>; Department of Surgery, Sylvester Comprehensive Cancer Center, University of Miami, Miami, FL, USA; Department of Veterans Affairs, Miami Healthcare System, Miami, FL, USA.<br /><searchLink fieldCode="AU" term="%22Giordano+S%22">Giordano S</searchLink>; University of Torino, Candiolo Cancer Institute - FPO, IRCCS, Candiolo, Italy.<br /><searchLink fieldCode="AU" term="%22Ban+Y%22">Ban Y</searchLink>; Department of Public Health Sciences, Miller School of Medicine, University of Miami, Miami, FL, 33136, USA.<br /><searchLink fieldCode="AU" term="%22Bilbao+D%22">Bilbao D</searchLink>; Sylvester Comprehensive Cancer Center, Miami, FL, USA; Department of Pathology, Miller School of Medicine, University of Miami, USA.<br /><searchLink fieldCode="AU" term="%22Chen+Z%22">Chen Z</searchLink>; Department of Surgery, Sylvester Comprehensive Cancer Center, University of Miami, Miami, FL, USA. Electronic address: zheng.chen@med.miami.edu.
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  Data: <searchLink fieldCode="JN" term="%227600053%22">Cancer letters</searchLink> [Cancer Lett] 2026 May 28; Vol. 646, pp. 218418. <i>Date of Electronic Publication: </i>2026 Mar 10.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Elsevier+Science+Ireland%22">Elsevier Science Ireland </searchLink><i>Country of Publication: </i>Ireland <i>NLM ID: </i>7600053 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1872-7980 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2203043835%22">03043835 </searchLink><i>NLM ISO Abbreviation: </i>Cancer Lett <i>Subsets: </i>MEDLINE
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