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Factor VIII restores bone parameters and modulates muscle proteo-metabolome in Factor VIII knockout male mice.

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Title: Factor VIII restores bone parameters and modulates muscle proteo-metabolome in Factor VIII knockout male mice.
Authors: Babuty A; Nantes University Hospital, Department of Hemostasis, Nantes, France.; Nantes Université, CNRS, UMR6286, US2B, 2 Rue de la Houssinière, 44322, Nantes, France.; Institut de Cancérologie de l'Ouest, Heterogeneity and Precision Medicine laboratory, Blvd Jacques Monod, 44805, Saint-Herblain, France., Muñoz-Garcia J; Nantes Université, CNRS, UMR6286, US2B, 2 Rue de la Houssinière, 44322, Nantes, France.; Institut de Cancérologie de l'Ouest, Heterogeneity and Precision Medicine laboratory, Blvd Jacques Monod, 44805, Saint-Herblain, France., Christophe OD; INSERM, Université Paris-Saclay, U1176, Paris, France., Fradet L; Nantes Université, CNRS, UMR6286, US2B, 2 Rue de la Houssinière, 44322, Nantes, France.; Institut de Cancérologie de l'Ouest, Heterogeneity and Precision Medicine laboratory, Blvd Jacques Monod, 44805, Saint-Herblain, France., Taupin M; Institut de Cancérologie de l'Ouest, Pathology Research Platform, Saint-Herblain, France., Cochonneau D; Institut de Cancérologie de l'Ouest, Heterogeneity and Precision Medicine laboratory, Blvd Jacques Monod, 44805, Saint-Herblain, France., Ollivier E; Institut de Cancérologie de l'Ouest, Heterogeneity and Precision Medicine laboratory, Blvd Jacques Monod, 44805, Saint-Herblain, France., Driessler F; Bayer Consumer Care AG, TA Medical Affairs Hematology, Basel, Switzerland., Lange C; Bayer AG, Precision Medicine Markers, Berlin, Germany., Boychenko O; Bayer AG, Translational Sciences/Omics Research, Wuppertal, Germany., Heymann MF; Nantes Université, CNRS, UMR6286, US2B, 2 Rue de la Houssinière, 44322, Nantes, France.; Institut de Cancérologie de l'Ouest, Heterogeneity and Precision Medicine laboratory, Blvd Jacques Monod, 44805, Saint-Herblain, France.; Institut de Cancérologie de l'Ouest, Pathology Research Platform, Saint-Herblain, France., Heymann D; Nantes Université, CNRS, UMR6286, US2B, 2 Rue de la Houssinière, 44322, Nantes, France. dominique.heymann@univ-nantes.fr.; Institut de Cancérologie de l'Ouest, Heterogeneity and Precision Medicine laboratory, Blvd Jacques Monod, 44805, Saint-Herblain, France. dominique.heymann@univ-nantes.fr.; University of Sheffield, School of Medicine and Population Health, Sheffield, UK. dominique.heymann@univ-nantes.fr.
Source: Bone research [Bone Res] 2026 Mar 11; Vol. 14 (1). Date of Electronic Publication: 2026 Mar 11.
Publication Type: Journal Article
Journal Info: Publisher: West China School of Stomatology, Sichuan University Country of Publication: China NLM ID: 101608652 Publication Model: Electronic Cited Medium: Print ISSN: 2095-4700 (Print) Linking ISSN: 20954700 NLM ISO Abbreviation: Bone Res Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Factor VIII restores bone parameters and modulates muscle proteo-metabolome in Factor VIII knockout male mice.
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  Data: <searchLink fieldCode="AU" term="%22Babuty+A%22">Babuty A</searchLink>; Nantes University Hospital, Department of Hemostasis, Nantes, France.; Nantes Université, CNRS, UMR6286, US2B, 2 Rue de la Houssinière, 44322, Nantes, France.; Institut de Cancérologie de l'Ouest, Heterogeneity and Precision Medicine laboratory, Blvd Jacques Monod, 44805, Saint-Herblain, France.<br /><searchLink fieldCode="AU" term="%22Muñoz-Garcia+J%22">Muñoz-Garcia J</searchLink>; Nantes Université, CNRS, UMR6286, US2B, 2 Rue de la Houssinière, 44322, Nantes, France.; Institut de Cancérologie de l'Ouest, Heterogeneity and Precision Medicine laboratory, Blvd Jacques Monod, 44805, Saint-Herblain, France.<br /><searchLink fieldCode="AU" term="%22Christophe+OD%22">Christophe OD</searchLink>; INSERM, Université Paris-Saclay, U1176, Paris, France.<br /><searchLink fieldCode="AU" term="%22Fradet+L%22">Fradet L</searchLink>; Nantes Université, CNRS, UMR6286, US2B, 2 Rue de la Houssinière, 44322, Nantes, France.; Institut de Cancérologie de l'Ouest, Heterogeneity and Precision Medicine laboratory, Blvd Jacques Monod, 44805, Saint-Herblain, France.<br /><searchLink fieldCode="AU" term="%22Taupin+M%22">Taupin M</searchLink>; Institut de Cancérologie de l'Ouest, Pathology Research Platform, Saint-Herblain, France.<br /><searchLink fieldCode="AU" term="%22Cochonneau+D%22">Cochonneau D</searchLink>; Institut de Cancérologie de l'Ouest, Heterogeneity and Precision Medicine laboratory, Blvd Jacques Monod, 44805, Saint-Herblain, France.<br /><searchLink fieldCode="AU" term="%22Ollivier+E%22">Ollivier E</searchLink>; Institut de Cancérologie de l'Ouest, Heterogeneity and Precision Medicine laboratory, Blvd Jacques Monod, 44805, Saint-Herblain, France.<br /><searchLink fieldCode="AU" term="%22Driessler+F%22">Driessler F</searchLink>; Bayer Consumer Care AG, TA Medical Affairs Hematology, Basel, Switzerland.<br /><searchLink fieldCode="AU" term="%22Lange+C%22">Lange C</searchLink>; Bayer AG, Precision Medicine Markers, Berlin, Germany.<br /><searchLink fieldCode="AU" term="%22Boychenko+O%22">Boychenko O</searchLink>; Bayer AG, Translational Sciences/Omics Research, Wuppertal, Germany.<br /><searchLink fieldCode="AU" term="%22Heymann+MF%22">Heymann MF</searchLink>; Nantes Université, CNRS, UMR6286, US2B, 2 Rue de la Houssinière, 44322, Nantes, France.; Institut de Cancérologie de l'Ouest, Heterogeneity and Precision Medicine laboratory, Blvd Jacques Monod, 44805, Saint-Herblain, France.; Institut de Cancérologie de l'Ouest, Pathology Research Platform, Saint-Herblain, France.<br /><searchLink fieldCode="AU" term="%22Heymann+D%22">Heymann D</searchLink>; Nantes Université, CNRS, UMR6286, US2B, 2 Rue de la Houssinière, 44322, Nantes, France. dominique.heymann@univ-nantes.fr.; Institut de Cancérologie de l'Ouest, Heterogeneity and Precision Medicine laboratory, Blvd Jacques Monod, 44805, Saint-Herblain, France. dominique.heymann@univ-nantes.fr.; University of Sheffield, School of Medicine and Population Health, Sheffield, UK. dominique.heymann@univ-nantes.fr.
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  Data: <searchLink fieldCode="JN" term="%22101608652%22">Bone research</searchLink> [Bone Res] 2026 Mar 11; Vol. 14 (1). <i>Date of Electronic Publication: </i>2026 Mar 11.
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