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Tumour specific HORMAD1 expression perturbs mitotic arrest and drives sensitivity to mitotic kinase inhibitors.

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Title: Tumour specific HORMAD1 expression perturbs mitotic arrest and drives sensitivity to mitotic kinase inhibitors.
Authors: Walker C; The Breast Cancer Now Toby Robins Research Centre, The Institute of Cancer Research, London, UK., Kollarovic G; The Breast Cancer Now Toby Robins Research Centre, The Institute of Cancer Research, London, UK., Weekes D; The Breast Cancer Now Toby Robins Research Centre, The Institute of Cancer Research, London, UK., Trendell J; The Breast Cancer Now Research Unit, King's College London, London, UK., Hoffmann RM; The Breast Cancer Now Toby Robins Research Centre, The Institute of Cancer Research, London, UK., Martin A; The Breast Cancer Now Toby Robins Research Centre, The Institute of Cancer Research, London, UK., Ferro R; The Breast Cancer Now Toby Robins Research Centre, The Institute of Cancer Research, London, UK.; The Breast Cancer Now Research Unit, King's College London, London, UK., Navarro-Llinas B; The Breast Cancer Now Research Unit, King's College London, London, UK., Hitchen L; The Breast Cancer Now Research Unit, King's College London, London, UK., Pardo Calvo M; The Institute of Cancer Research, London, UK., Balan N; The Breast Cancer Now Toby Robins Research Centre, The Institute of Cancer Research, London, UK., Kemp H; The Breast Cancer Now Toby Robins Research Centre, The Institute of Cancer Research, London, UK., Carroll A; The Breast Cancer Now Toby Robins Research Centre, The Institute of Cancer Research, London, UK.; The Breast Cancer Now Research Unit, King's College London, London, UK., Davidson K; The Breast Cancer Now Toby Robins Research Centre, The Institute of Cancer Research, London, UK., Nath S; The Breast Cancer Now Toby Robins Research Centre, The Institute of Cancer Research, London, UK., D'Uonno N; The Breast Cancer Now Research Unit, King's College London, London, UK., Lu R; The Breast Cancer Now Research Unit, King's College London, London, UK., Starling C; The Breast Cancer Now Toby Robins Research Centre, The Institute of Cancer Research, London, UK., Otten M; The Breast Cancer Now Toby Robins Research Centre, The Institute of Cancer Research, London, UK., Iakobachvili N; The Breast Cancer Now Toby Robins Research Centre, The Institute of Cancer Research, London, UK., Marcozzi C; The Institute of Cancer Research, London, UK., Rahman I; The Breast Cancer Now Research Unit, King's College London, London, UK., Quist J; The Breast Cancer Now Research Unit, King's College London, London, UK., Yu L; The Institute of Cancer Research, London, UK., Krastev DB; The Breast Cancer Now Toby Robins Research Centre, The Institute of Cancer Research, London, UK., Amodeo V; The Breast Cancer Now Toby Robins Research Centre, The Institute of Cancer Research, London, UK., Roxanis I; The Breast Cancer Now Toby Robins Research Centre, The Institute of Cancer Research, London, UK., Grigoriadis A; The Breast Cancer Now Research Unit, King's College London, London, UK., Bayliss R; School of Molecular and Cellular Biology, Faculty of Biological Sciences, University of Leeds, Leeds, UK.; Astbury Centre for Structural Molecular Biology, University of Leeds, Leeds, UK., Choudhary J; The Institute of Cancer Research, London, UK., Haider S; The Breast Cancer Now Toby Robins Research Centre, The Institute of Cancer Research, London, UK., Pines J; The Institute of Cancer Research, London, UK., Pettitt SJ; The Breast Cancer Now Toby Robins Research Centre, The Institute of Cancer Research, London, UK. Stephen.Pettitt@icr.ac.uk., Lord CJ; The Breast Cancer Now Toby Robins Research Centre, The Institute of Cancer Research, London, UK. Chris.Lord@icr.ac.uk., Tutt ANJ; The Breast Cancer Now Toby Robins Research Centre, The Institute of Cancer Research, London, UK. Andrew.Tutt@icr.ac.uk.; The Breast Cancer Now Research Unit, King's College London, London, UK. Andrew.Tutt@icr.ac.uk.
Source: Nature communications [Nat Commun] 2026 Mar 11; Vol. 17 (1). Date of Electronic Publication: 2026 Mar 11.
Publication Type: Journal Article
Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE
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  Data: Tumour specific HORMAD1 expression perturbs mitotic arrest and drives sensitivity to mitotic kinase inhibitors.
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The Institute of Cancer Research, London, UK.<br /><searchLink fieldCode="AU" term="%22Pettitt+SJ%22">Pettitt SJ</searchLink>; The Breast Cancer Now Toby Robins Research Centre, The Institute of Cancer Research, London, UK. Stephen.Pettitt@icr.ac.uk.<br /><searchLink fieldCode="AU" term="%22Lord+CJ%22">Lord CJ</searchLink>; The Breast Cancer Now Toby Robins Research Centre, The Institute of Cancer Research, London, UK. Chris.Lord@icr.ac.uk.<br /><searchLink fieldCode="AU" term="%22Tutt+ANJ%22">Tutt ANJ</searchLink>; The Breast Cancer Now Toby Robins Research Centre, The Institute of Cancer Research, London, UK. Andrew.Tutt@icr.ac.uk.; The Breast Cancer Now Research Unit, King's College London, London, UK. Andrew.Tutt@icr.ac.uk.
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