Precise metabolomics identifies glycolysis-related pyruvate kinase M activity as regulator of the S-phase-specific radiation response in triple-negative breast cancer cells.
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| Title: | Precise metabolomics identifies glycolysis-related pyruvate kinase M activity as regulator of the S-phase-specific radiation response in triple-negative breast cancer cells. |
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| Authors: | Matesanz-Sánchez R; OncoRay-National Center for Radiation Research in Oncology, Faculty of Medicine Carl Gustav Carus, Technische Universität Dresden, Dresden, 01307, Germany., Classen S; Department of Radiotherapy & Radiation Oncology, Hubertus Wald Tumor Center, University Cancer Center Hamburg, University Medical Center Hamburg-Eppendorf, Hamburg, 20246, Germany., Siniuk K; Project Group Biochemistry, Leibniz Institute on Aging - Fritz Lipmann Institute, Jena, 07745, Germany., Peitzsch M; Institute of Clinical Chemistry and Laboratory Medicine, University Hospital Carl Gustav Carus, Technische Universität, Dresden, 01307, Germany., Alves T; Institute for Medical Informatics and Biometry (IMB), Technische Universität Dresden, 01307, Dresden, Germany., Pospiech H; Project Group Biochemistry, Leibniz Institute on Aging - Fritz Lipmann Institute, Jena, 07745, Germany.; Faculty of Biochemistry and Molecular Medicine, University of Oulu, Oulu, 90014, Finland.; Research laboratory of the Clinic for Gynecology and Obstetrics, University Hospital Düsseldorf, Düsseldorf, Germany., Borgmann K; Department of Radiotherapy & Radiation Oncology, Hubertus Wald Tumor Center, University Cancer Center Hamburg, University Medical Center Hamburg-Eppendorf, Hamburg, 20246, Germany. borgmann@uke.de., Cordes N; OncoRay-National Center for Radiation Research in Oncology, Faculty of Medicine Carl Gustav Carus, Technische Universität Dresden, Dresden, 01307, Germany. nils.cordes@oncoray.de.; Institute of Radiooncology- OncoRay, Helmholtz-Zentrum Dresden-Rossendorf (HZDR), Dresden, 01328, Germany. nils.cordes@oncoray.de.; German Cancer Consortium (DKTK), German Cancer Research Center (DKFZ), Heidelberg, 69120, Germany. nils.cordes@oncoray.de.; Department of Radiotherapy and Radiation Oncology, University Hospital Carl Gustav Carus, Technische Universität Dresden, Dresden, 01307, Germany. nils.cordes@oncoray.de. |
| Source: | Cell communication and signaling : CCS [Cell Commun Signal] 2026 Mar 12; Vol. 24 (1). Date of Electronic Publication: 2026 Mar 12. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: BioMed Central Country of Publication: England NLM ID: 101170464 Publication Model: Electronic Cited Medium: Internet ISSN: 1478-811X (Electronic) Linking ISSN: 1478811X NLM ISO Abbreviation: Cell Commun Signal Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
| FullText | Text: Availability: 0 |
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| Header | DbId: mdl DbLabel: MEDLINE Ultimate An: 41814308 AccessLevel: 2 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: Precise metabolomics identifies glycolysis-related pyruvate kinase M activity as regulator of the S-phase-specific radiation response in triple-negative breast cancer cells. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AU" term="%22Matesanz-Sánchez+R%22">Matesanz-Sánchez R</searchLink>; OncoRay-National Center for Radiation Research in Oncology, Faculty of Medicine Carl Gustav Carus, Technische Universität Dresden, Dresden, 01307, Germany.<br /><searchLink fieldCode="AU" term="%22Classen+S%22">Classen S</searchLink>; Department of Radiotherapy & Radiation Oncology, Hubertus Wald Tumor Center, University Cancer Center Hamburg, University Medical Center Hamburg-Eppendorf, Hamburg, 20246, Germany.<br /><searchLink fieldCode="AU" term="%22Siniuk+K%22">Siniuk K</searchLink>; Project Group Biochemistry, Leibniz Institute on Aging - Fritz Lipmann Institute, Jena, 07745, Germany.<br /><searchLink fieldCode="AU" term="%22Peitzsch+M%22">Peitzsch M</searchLink>; Institute of Clinical Chemistry and Laboratory Medicine, University Hospital Carl Gustav Carus, Technische Universität, Dresden, 01307, Germany.<br /><searchLink fieldCode="AU" term="%22Alves+T%22">Alves T</searchLink>; Institute for Medical Informatics and Biometry (IMB), Technische Universität Dresden, 01307, Dresden, Germany.<br /><searchLink fieldCode="AU" term="%22Pospiech+H%22">Pospiech H</searchLink>; Project Group Biochemistry, Leibniz Institute on Aging - Fritz Lipmann Institute, Jena, 07745, Germany.; Faculty of Biochemistry and Molecular Medicine, University of Oulu, Oulu, 90014, Finland.; Research laboratory of the Clinic for Gynecology and Obstetrics, University Hospital Düsseldorf, Düsseldorf, Germany.<br /><searchLink fieldCode="AU" term="%22Borgmann+K%22">Borgmann K</searchLink>; Department of Radiotherapy & Radiation Oncology, Hubertus Wald Tumor Center, University Cancer Center Hamburg, University Medical Center Hamburg-Eppendorf, Hamburg, 20246, Germany. borgmann@uke.de.<br /><searchLink fieldCode="AU" term="%22Cordes+N%22">Cordes N</searchLink>; OncoRay-National Center for Radiation Research in Oncology, Faculty of Medicine Carl Gustav Carus, Technische Universität Dresden, Dresden, 01307, Germany. nils.cordes@oncoray.de.; Institute of Radiooncology- OncoRay, Helmholtz-Zentrum Dresden-Rossendorf (HZDR), Dresden, 01328, Germany. nils.cordes@oncoray.de.; German Cancer Consortium (DKTK), German Cancer Research Center (DKFZ), Heidelberg, 69120, Germany. nils.cordes@oncoray.de.; Department of Radiotherapy and Radiation Oncology, University Hospital Carl Gustav Carus, Technische Universität Dresden, Dresden, 01307, Germany. nils.cordes@oncoray.de. – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%22101170464%22">Cell communication and signaling : CCS</searchLink> [Cell Commun Signal] 2026 Mar 12; Vol. 24 (1). <i>Date of Electronic Publication: </i>2026 Mar 12. – Name: TypePub Label: Publication Type Group: TypPub Data: Journal Article – Name: TitleSource Label: Journal Info Group: Src Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22BioMed+Central%22">BioMed Central </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>101170464 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1478-811X (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%221478811X%22">1478811X </searchLink><i>NLM ISO Abbreviation: </i>Cell Commun Signal <i>Subsets: </i>MEDLINE |
| PLink | https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=41814308 |
| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1186/s12964-026-02803-5 Languages: – Code: eng Text: English Titles: – TitleFull: Precise metabolomics identifies glycolysis-related pyruvate kinase M activity as regulator of the S-phase-specific radiation response in triple-negative breast cancer cells. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Matesanz-Sánchez R – PersonEntity: Name: NameFull: Classen S – PersonEntity: Name: NameFull: Siniuk K – PersonEntity: Name: NameFull: Peitzsch M – PersonEntity: Name: NameFull: Alves T – PersonEntity: Name: NameFull: Pospiech H – PersonEntity: Name: NameFull: Borgmann K – PersonEntity: Name: NameFull: Cordes N IsPartOfRelationships: – BibEntity: Dates: – D: 12 M: 03 Text: 2026 Mar 12 Type: published Y: 2026 Identifiers: – Type: issn-electronic Value: 1478-811X Numbering: – Type: volume Value: 24 – Type: issue Value: 1 Titles: – TitleFull: Cell communication and signaling : CCS Type: main |
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