Dual roles of GDNF in enteric glial cell plasticity: direct transdifferentiation via the CaMKII/NeuroD1 pathway and cooperative regulation in a neural stem cell-inducing medium.
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| Title: | Dual roles of GDNF in enteric glial cell plasticity: direct transdifferentiation via the CaMKII/NeuroD1 pathway and cooperative regulation in a neural stem cell-inducing medium. |
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| Authors: | Jia W; Department of Pediatric Surgery, The Second Affiliated Hospital, Xi'an Jiaotong University, No 157, Xi Wu Road, Xi'an, 710004, China.; Institute of Neurobiology, Environment and Genes Related to Diseases Key Laboratory of Chinese Ministry of Education, Xi'an Jiaotong University, No 76, Yan Ta Xi Road, Xi'an, 710061, China.; Department of Pediatric Surgery, Luoyang Central Hospital, No.288 Zhongzhou Middle Road, Luoyang, 471000, China., Yan H; Department of Pediatric Surgery, The Second Affiliated Hospital, Xi'an Jiaotong University, No 157, Xi Wu Road, Xi'an, 710004, China.; Institute of Neurobiology, Environment and Genes Related to Diseases Key Laboratory of Chinese Ministry of Education, Xi'an Jiaotong University, No 76, Yan Ta Xi Road, Xi'an, 710061, China., Huang J; Department of Pediatric Surgery, The Second Affiliated Hospital, Xi'an Jiaotong University, No 157, Xi Wu Road, Xi'an, 710004, China.; Institute of Neurobiology, Environment and Genes Related to Diseases Key Laboratory of Chinese Ministry of Education, Xi'an Jiaotong University, No 76, Yan Ta Xi Road, Xi'an, 710061, China., Liu W; Department of Pediatric Surgery, The Second Affiliated Hospital, Xi'an Jiaotong University, No 157, Xi Wu Road, Xi'an, 710004, China.; Institute of Neurobiology, Environment and Genes Related to Diseases Key Laboratory of Chinese Ministry of Education, Xi'an Jiaotong University, No 76, Yan Ta Xi Road, Xi'an, 710061, China., Fu Z; Department of Pediatric Surgery, The Second Affiliated Hospital, Xi'an Jiaotong University, No 157, Xi Wu Road, Xi'an, 710004, China.; Institute of Neurobiology, Environment and Genes Related to Diseases Key Laboratory of Chinese Ministry of Education, Xi'an Jiaotong University, No 76, Yan Ta Xi Road, Xi'an, 710061, China., Tian D; Department of Pediatric Surgery, The Second Affiliated Hospital, Xi'an Jiaotong University, No 157, Xi Wu Road, Xi'an, 710004, China.; Institute of Neurobiology, Environment and Genes Related to Diseases Key Laboratory of Chinese Ministry of Education, Xi'an Jiaotong University, No 76, Yan Ta Xi Road, Xi'an, 710061, China., Xu W; Department of Pediatric Surgery, The Second Affiliated Hospital, Xi'an Jiaotong University, No 157, Xi Wu Road, Xi'an, 710004, China.; Institute of Neurobiology, Environment and Genes Related to Diseases Key Laboratory of Chinese Ministry of Education, Xi'an Jiaotong University, No 76, Yan Ta Xi Road, Xi'an, 710061, China., Chen X; Institute of Neurobiology, Environment and Genes Related to Diseases Key Laboratory of Chinese Ministry of Education, Xi'an Jiaotong University, No 76, Yan Ta Xi Road, Xi'an, 710061, China., Gao Y; Department of Pediatric Surgery, The Second Affiliated Hospital, Xi'an Jiaotong University, No 157, Xi Wu Road, Xi'an, 710004, China. ygao@xjtu.edu.cn., Yu H; Department of Pediatric Surgery, The Second Affiliated Hospital, Xi'an Jiaotong University, No 157, Xi Wu Road, Xi'an, 710004, China. yuhui831022@xjtu.edu.cn.; Department of Pediatric Surgery, Luoyang Central Hospital, No.288 Zhongzhou Middle Road, Luoyang, 471000, China. yuhui831022@xjtu.edu.cn. |
| Source: | Stem cell research & therapy [Stem Cell Res Ther] 2026 Mar 11; Vol. 17 (1). Date of Electronic Publication: 2026 Mar 11. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: BioMed Central Country of Publication: England NLM ID: 101527581 Publication Model: Electronic Cited Medium: Internet ISSN: 1757-6512 (Electronic) Linking ISSN: 17576512 NLM ISO Abbreviation: Stem Cell Res Ther Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
| FullText | Text: Availability: 0 |
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| Header | DbId: mdl DbLabel: MEDLINE Ultimate An: 41814387 AccessLevel: 2 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: Dual roles of GDNF in enteric glial cell plasticity: direct transdifferentiation via the CaMKII/NeuroD1 pathway and cooperative regulation in a neural stem cell-inducing medium. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AU" term="%22Jia+W%22">Jia W</searchLink>; Department of Pediatric Surgery, The Second Affiliated Hospital, Xi'an Jiaotong University, No 157, Xi Wu Road, Xi'an, 710004, China.; Institute of Neurobiology, Environment and Genes Related to Diseases Key Laboratory of Chinese Ministry of Education, Xi'an Jiaotong University, No 76, Yan Ta Xi Road, Xi'an, 710061, China.; Department of Pediatric Surgery, Luoyang Central Hospital, No.288 Zhongzhou Middle Road, Luoyang, 471000, China.<br /><searchLink fieldCode="AU" term="%22Yan+H%22">Yan H</searchLink>; Department of Pediatric Surgery, The Second Affiliated Hospital, Xi'an Jiaotong University, No 157, Xi Wu Road, Xi'an, 710004, China.; Institute of Neurobiology, Environment and Genes Related to Diseases Key Laboratory of Chinese Ministry of Education, Xi'an Jiaotong University, No 76, Yan Ta Xi Road, Xi'an, 710061, China.<br /><searchLink fieldCode="AU" term="%22Huang+J%22">Huang J</searchLink>; Department of Pediatric Surgery, The Second Affiliated Hospital, Xi'an Jiaotong University, No 157, Xi Wu Road, Xi'an, 710004, China.; Institute of Neurobiology, Environment and Genes Related to Diseases Key Laboratory of Chinese Ministry of Education, Xi'an Jiaotong University, No 76, Yan Ta Xi Road, Xi'an, 710061, China.<br /><searchLink fieldCode="AU" term="%22Liu+W%22">Liu W</searchLink>; Department of Pediatric Surgery, The Second Affiliated Hospital, Xi'an Jiaotong University, No 157, Xi Wu Road, Xi'an, 710004, China.; Institute of Neurobiology, Environment and Genes Related to Diseases Key Laboratory of Chinese Ministry of Education, Xi'an Jiaotong University, No 76, Yan Ta Xi Road, Xi'an, 710061, China.<br /><searchLink fieldCode="AU" term="%22Fu+Z%22">Fu Z</searchLink>; Department of Pediatric Surgery, The Second Affiliated Hospital, Xi'an Jiaotong University, No 157, Xi Wu Road, Xi'an, 710004, China.; Institute of Neurobiology, Environment and Genes Related to Diseases Key Laboratory of Chinese Ministry of Education, Xi'an Jiaotong University, No 76, Yan Ta Xi Road, Xi'an, 710061, China.<br /><searchLink fieldCode="AU" term="%22Tian+D%22">Tian D</searchLink>; Department of Pediatric Surgery, The Second Affiliated Hospital, Xi'an Jiaotong University, No 157, Xi Wu Road, Xi'an, 710004, China.; Institute of Neurobiology, Environment and Genes Related to Diseases Key Laboratory of Chinese Ministry of Education, Xi'an Jiaotong University, No 76, Yan Ta Xi Road, Xi'an, 710061, China.<br /><searchLink fieldCode="AU" term="%22Xu+W%22">Xu W</searchLink>; Department of Pediatric Surgery, The Second Affiliated Hospital, Xi'an Jiaotong University, No 157, Xi Wu Road, Xi'an, 710004, China.; Institute of Neurobiology, Environment and Genes Related to Diseases Key Laboratory of Chinese Ministry of Education, Xi'an Jiaotong University, No 76, Yan Ta Xi Road, Xi'an, 710061, China.<br /><searchLink fieldCode="AU" term="%22Chen+X%22">Chen X</searchLink>; Institute of Neurobiology, Environment and Genes Related to Diseases Key Laboratory of Chinese Ministry of Education, Xi'an Jiaotong University, No 76, Yan Ta Xi Road, Xi'an, 710061, China.<br /><searchLink fieldCode="AU" term="%22Gao+Y%22">Gao Y</searchLink>; Department of Pediatric Surgery, The Second Affiliated Hospital, Xi'an Jiaotong University, No 157, Xi Wu Road, Xi'an, 710004, China. ygao@xjtu.edu.cn.<br /><searchLink fieldCode="AU" term="%22Yu+H%22">Yu H</searchLink>; Department of Pediatric Surgery, The Second Affiliated Hospital, Xi'an Jiaotong University, No 157, Xi Wu Road, Xi'an, 710004, China. yuhui831022@xjtu.edu.cn.; Department of Pediatric Surgery, Luoyang Central Hospital, No.288 Zhongzhou Middle Road, Luoyang, 471000, China. yuhui831022@xjtu.edu.cn. – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%22101527581%22">Stem cell research & therapy</searchLink> [Stem Cell Res Ther] 2026 Mar 11; Vol. 17 (1). <i>Date of Electronic Publication: </i>2026 Mar 11. – Name: TypePub Label: Publication Type Group: TypPub Data: Journal Article – Name: TitleSource Label: Journal Info Group: Src Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22BioMed+Central%22">BioMed Central </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>101527581 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1757-6512 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2217576512%22">17576512 </searchLink><i>NLM ISO Abbreviation: </i>Stem Cell Res Ther <i>Subsets: </i>MEDLINE |
| PLink | https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=41814387 |
| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1186/s13287-026-04966-x Languages: – Code: eng Text: English Titles: – TitleFull: Dual roles of GDNF in enteric glial cell plasticity: direct transdifferentiation via the CaMKII/NeuroD1 pathway and cooperative regulation in a neural stem cell-inducing medium. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Jia W – PersonEntity: Name: NameFull: Yan H – PersonEntity: Name: NameFull: Huang J – PersonEntity: Name: NameFull: Liu W – PersonEntity: Name: NameFull: Fu Z – PersonEntity: Name: NameFull: Tian D – PersonEntity: Name: NameFull: Xu W – PersonEntity: Name: NameFull: Chen X – PersonEntity: Name: NameFull: Gao Y – PersonEntity: Name: NameFull: Yu H IsPartOfRelationships: – BibEntity: Dates: – D: 11 M: 03 Text: 2026 Mar 11 Type: published Y: 2026 Identifiers: – Type: issn-electronic Value: 1757-6512 Numbering: – Type: volume Value: 17 – Type: issue Value: 1 Titles: – TitleFull: Stem cell research & therapy Type: main |
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