Laterally spreading AAV.SPR enables safe and efficient RS1 delivery to the macula after peripheral subretinal injection.
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| Title: | Laterally spreading AAV.SPR enables safe and efficient RS1 delivery to the macula after peripheral subretinal injection. |
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| Authors: | Andres-Mateos E; Atsena Therapeutics, Durham, NC 27709, USA., Kozlowski C; Atsena Therapeutics, Durham, NC 27709, USA., Zhang H; Divison of Cellular and Molecular Therapy, Department of Pediatrics, University of Florida, Gainesville, FL 32610, USA., Fajardo D; Divison of Cellular and Molecular Therapy, Department of Pediatrics, University of Florida, Gainesville, FL 32610, USA., Xu E; Divison of Cellular and Molecular Therapy, Department of Pediatrics, University of Florida, Gainesville, FL 32610, USA., Enamorado IN; Atsena Therapeutics, Durham, NC 27709, USA., Calabro KR; Atsena Therapeutics, Durham, NC 27709, USA., Rayaprolu S; Atsena Therapeutics, Durham, NC 27709, USA., Havlik LP; Atsena Therapeutics, Durham, NC 27709, USA., Handy TE; Atsena Therapeutics, Durham, NC 27709, USA., Plummer CE; Department of Small Animal Clinical Sciences, College of Veterinary Medicine, University of Florida, Gainesville, FL 32610, USA., Stevenson V; Ophthalmology Services, Charles River Laboratories, Mattawan, MI, USA., Rind H; Ophthalmology Services, Charles River Laboratories, Mattawan, MI, USA., Leahy M; Ophthalmology Services, Charles River Laboratories, Mattawan, MI, USA., Boyd RF; Ophthalmology Services, Charles River Laboratories, Mattawan, MI, USA., Coleman KE; Powell Gene Therapy Center, Department of Pediatrics, University of Florida, Gainesville, FL 32610, USA., Boye SL; Powell Gene Therapy Center, Department of Pediatrics, University of Florida, Gainesville, FL 32610, USA., Boye SE; Atsena Therapeutics, Durham, NC 27709, USA. Electronic address: shannon.boye@atsenatx.com. |
| Source: | Molecular therapy : the journal of the American Society of Gene Therapy [Mol Ther] 2026 Jul 01; Vol. 34 (7), pp. 3838-3853. Date of Electronic Publication: 2026 Mar 11. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Cell Press Country of Publication: United States NLM ID: 100890581 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1525-0024 (Electronic) Linking ISSN: 15250016 NLM ISO Abbreviation: Mol Ther Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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