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Tumor morphology on CT radiomics is largely driven by the local anatomical environment, not the primary tumor type.

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Title: Tumor morphology on CT radiomics is largely driven by the local anatomical environment, not the primary tumor type.
Authors: Rostami S; Department of Radiology, The Netherlands Cancer Institute, Amsterdam, The Netherlands.; GROW Research Institute for Oncology and Reproduction, Maastricht University, Maastricht, The Netherlands., Guérendel C; Department of Radiology, The Netherlands Cancer Institute, Amsterdam, The Netherlands.; GROW Research Institute for Oncology and Reproduction, Maastricht University, Maastricht, The Netherlands., Soliman M; Department of Radiology, The Netherlands Cancer Institute, Amsterdam, The Netherlands., Stutterheim HW; Department of Radiology, The Netherlands Cancer Institute, Amsterdam, The Netherlands., Maxouri O; Department of Radiology, The Netherlands Cancer Institute, Amsterdam, The Netherlands.; GROW Research Institute for Oncology and Reproduction, Maastricht University, Maastricht, The Netherlands., Rodríguez Sánchez DI; Department of Radiology, The Netherlands Cancer Institute, Amsterdam, The Netherlands.; GROW Research Institute for Oncology and Reproduction, Maastricht University, Maastricht, The Netherlands., Ursprung S; Department of Radiology, The Netherlands Cancer Institute, Amsterdam, The Netherlands.; Department of Diagnostic and Interventional Radiology, Tübingen University Hospital, Karls-Eberhardt University, Tübingen, Germany., Boveradze N; Department of Radiology, The Netherlands Cancer Institute, Amsterdam, The Netherlands.; GROW Research Institute for Oncology and Reproduction, Maastricht University, Maastricht, The Netherlands.; Department of Radiology, American Hospital Tbilisi, Tbilisi, Georgia., Agrotis G; Department of Radiology, The Netherlands Cancer Institute, Amsterdam, The Netherlands.; GROW Research Institute for Oncology and Reproduction, Maastricht University, Maastricht, The Netherlands., Chupetlovska K; Department of Radiology, The Netherlands Cancer Institute, Amsterdam, The Netherlands.; GROW Research Institute for Oncology and Reproduction, Maastricht University, Maastricht, The Netherlands., Castagnoli F; Department of Radiology, Royal Marsden Hospital, London, UK.; Division of Radiotherapy and Imaging, The Institute of Cancer Research, London, UK., Landolfi F; Radiology Unit, Sant'Andrea Hospital, Sapienza University of Rome, Rome, Italy., Hong EK; Department of Radiology, Stanford University, Palo Alto, CA, USA., Pizzi AD; Department of Innovative Technologies in Medicine & Dentistry, G. d'Annunzio University of Chieti-Pescara, Chieti, Italy.; Institute for Advanced Biomedical Technologies, G. d'Annunzio University of Chieti-Pescara, Chieti, Italy., Gennaro N; Feinberg School of Medicine, Northwestern University, Chicago, IL, USA.; Clinic of Radiology, Imaging Institute of Southern Switzerland (IIMSI), Ente Ospedaliero Cantonale (EOC), Lugano, Switzerland., Abdelatty MA; Department of Radiology, Kasr Al-Ainy Hospital, Cairo University, Cairo, Egypt., Jutidamrongphan W; Department of Nuclear Medicine, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland., Petrychenko L; Department of Radiology, The Netherlands Cancer Institute, Amsterdam, The Netherlands.; GROW Research Institute for Oncology and Reproduction, Maastricht University, Maastricht, The Netherlands., Matkulcik P; Department of Radiology and Nuclear Medicine, University Hospital Brno, Brno, Czechia., Salgado-Parente A; Department of Radiology, Ramón y Cajal University Hospital, Madrid, Spain., Arico FM; Diagnostic and Interventional Radiology Unit, BIOMORF Department, University Hospital 'Policlinico G. Martino', Messina, Italy., Benson S; Department of Radiology, The Netherlands Cancer Institute, Amsterdam, The Netherlands.; Department of Cardiology, Amsterdam University Medical Center, University of Amsterdam, Amsterdam, The Netherlands., Snaebjornsson P; Department of Pathology, The Netherlands Cancer Institute, Amsterdam, The Netherlands.; Faculty of Medicine, University of Iceland, Reykjavik, Iceland., Bodalal Z; Department of Radiology, The Netherlands Cancer Institute, Amsterdam, The Netherlands.; GROW Research Institute for Oncology and Reproduction, Maastricht University, Maastricht, The Netherlands., Beets-Tan RGH; GROW Research Institute for Oncology and Reproduction, Maastricht University, Maastricht, The Netherlands. r.beetstan@nki.nl.; The Netherlands Cancer Institute, Amsterdam, The Netherlands. r.beetstan@nki.nl.; Faculty of Health Sciences, University of Southern Denmark, Odense, Denmark. r.beetstan@nki.nl.; Maastricht Radiation Oncology, Maastricht, The Netherlands. r.beetstan@nki.nl.
Source: European radiology experimental [Eur Radiol Exp] 2026 Mar 12; Vol. 10 (1). Date of Electronic Publication: 2026 Mar 12.
Publication Type: Journal Article
Journal Info: Publisher: SpringerOpen Country of Publication: England NLM ID: 101721752 Publication Model: Electronic Cited Medium: Internet ISSN: 2509-9280 (Electronic) Linking ISSN: 25099280 NLM ISO Abbreviation: Eur Radiol Exp Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Tumor morphology on CT radiomics is largely driven by the local anatomical environment, not the primary tumor type.
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  Data: <searchLink fieldCode="AU" term="%22Rostami+S%22">Rostami S</searchLink>; Department of Radiology, The Netherlands Cancer Institute, Amsterdam, The Netherlands.; GROW Research Institute for Oncology and Reproduction, Maastricht University, Maastricht, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Guérendel+C%22">Guérendel C</searchLink>; Department of Radiology, The Netherlands Cancer Institute, Amsterdam, The Netherlands.; GROW Research Institute for Oncology and Reproduction, Maastricht University, Maastricht, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Soliman+M%22">Soliman M</searchLink>; Department of Radiology, The Netherlands Cancer Institute, Amsterdam, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Stutterheim+HW%22">Stutterheim HW</searchLink>; Department of Radiology, The Netherlands Cancer Institute, Amsterdam, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Maxouri+O%22">Maxouri O</searchLink>; Department of Radiology, The Netherlands Cancer Institute, Amsterdam, The Netherlands.; GROW Research Institute for Oncology and Reproduction, Maastricht University, Maastricht, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Rodríguez+Sánchez+DI%22">Rodríguez Sánchez DI</searchLink>; Department of Radiology, The Netherlands Cancer Institute, Amsterdam, The Netherlands.; GROW Research Institute for Oncology and Reproduction, Maastricht University, Maastricht, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Ursprung+S%22">Ursprung S</searchLink>; Department of Radiology, The Netherlands Cancer Institute, Amsterdam, The Netherlands.; Department of Diagnostic and Interventional Radiology, Tübingen University Hospital, Karls-Eberhardt University, Tübingen, Germany.<br /><searchLink fieldCode="AU" term="%22Boveradze+N%22">Boveradze N</searchLink>; Department of Radiology, The Netherlands Cancer Institute, Amsterdam, The Netherlands.; GROW Research Institute for Oncology and Reproduction, Maastricht University, Maastricht, The Netherlands.; Department of Radiology, American Hospital Tbilisi, Tbilisi, Georgia.<br /><searchLink fieldCode="AU" term="%22Agrotis+G%22">Agrotis G</searchLink>; Department of Radiology, The Netherlands Cancer Institute, Amsterdam, The Netherlands.; GROW Research Institute for Oncology and Reproduction, Maastricht University, Maastricht, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Chupetlovska+K%22">Chupetlovska K</searchLink>; Department of Radiology, The Netherlands Cancer Institute, Amsterdam, The Netherlands.; GROW Research Institute for Oncology and Reproduction, Maastricht University, Maastricht, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Castagnoli+F%22">Castagnoli F</searchLink>; Department of Radiology, Royal Marsden Hospital, London, UK.; Division of Radiotherapy and Imaging, The Institute of Cancer Research, London, UK.<br /><searchLink fieldCode="AU" term="%22Landolfi+F%22">Landolfi F</searchLink>; Radiology Unit, Sant'Andrea Hospital, Sapienza University of Rome, Rome, Italy.<br /><searchLink fieldCode="AU" term="%22Hong+EK%22">Hong EK</searchLink>; Department of Radiology, Stanford University, Palo Alto, CA, USA.<br /><searchLink fieldCode="AU" term="%22Pizzi+AD%22">Pizzi AD</searchLink>; Department of Innovative Technologies in Medicine & Dentistry, G. d'Annunzio University of Chieti-Pescara, Chieti, Italy.; Institute for Advanced Biomedical Technologies, G. d'Annunzio University of Chieti-Pescara, Chieti, Italy.<br /><searchLink fieldCode="AU" term="%22Gennaro+N%22">Gennaro N</searchLink>; Feinberg School of Medicine, Northwestern University, Chicago, IL, USA.; Clinic of Radiology, Imaging Institute of Southern Switzerland (IIMSI), Ente Ospedaliero Cantonale (EOC), Lugano, Switzerland.<br /><searchLink fieldCode="AU" term="%22Abdelatty+MA%22">Abdelatty MA</searchLink>; Department of Radiology, Kasr Al-Ainy Hospital, Cairo University, Cairo, Egypt.<br /><searchLink fieldCode="AU" term="%22Jutidamrongphan+W%22">Jutidamrongphan W</searchLink>; Department of Nuclear Medicine, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland.<br /><searchLink fieldCode="AU" term="%22Petrychenko+L%22">Petrychenko L</searchLink>; Department of Radiology, The Netherlands Cancer Institute, Amsterdam, The Netherlands.; GROW Research Institute for Oncology and Reproduction, Maastricht University, Maastricht, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Matkulcik+P%22">Matkulcik P</searchLink>; Department of Radiology and Nuclear Medicine, University Hospital Brno, Brno, Czechia.<br /><searchLink fieldCode="AU" term="%22Salgado-Parente+A%22">Salgado-Parente A</searchLink>; Department of Radiology, Ramón y Cajal University Hospital, Madrid, Spain.<br /><searchLink fieldCode="AU" term="%22Arico+FM%22">Arico FM</searchLink>; Diagnostic and Interventional Radiology Unit, BIOMORF Department, University Hospital 'Policlinico G. Martino', Messina, Italy.<br /><searchLink fieldCode="AU" term="%22Benson+S%22">Benson S</searchLink>; Department of Radiology, The Netherlands Cancer Institute, Amsterdam, The Netherlands.; Department of Cardiology, Amsterdam University Medical Center, University of Amsterdam, Amsterdam, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Snaebjornsson+P%22">Snaebjornsson P</searchLink>; Department of Pathology, The Netherlands Cancer Institute, Amsterdam, The Netherlands.; Faculty of Medicine, University of Iceland, Reykjavik, Iceland.<br /><searchLink fieldCode="AU" term="%22Bodalal+Z%22">Bodalal Z</searchLink>; Department of Radiology, The Netherlands Cancer Institute, Amsterdam, The Netherlands.; GROW Research Institute for Oncology and Reproduction, Maastricht University, Maastricht, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Beets-Tan+RGH%22">Beets-Tan RGH</searchLink>; GROW Research Institute for Oncology and Reproduction, Maastricht University, Maastricht, The Netherlands. r.beetstan@nki.nl.; The Netherlands Cancer Institute, Amsterdam, The Netherlands. r.beetstan@nki.nl.; Faculty of Health Sciences, University of Southern Denmark, Odense, Denmark. r.beetstan@nki.nl.; Maastricht Radiation Oncology, Maastricht, The Netherlands. r.beetstan@nki.nl.
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  Data: <searchLink fieldCode="JN" term="%22101721752%22">European radiology experimental</searchLink> [Eur Radiol Exp] 2026 Mar 12; Vol. 10 (1). <i>Date of Electronic Publication: </i>2026 Mar 12.
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