An Fc-silent OspA monoclonal antibody passively protects mice from tick and intradermal Borrelia burgdorferi challenge.

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Title: An Fc-silent OspA monoclonal antibody passively protects mice from tick and intradermal Borrelia burgdorferi challenge.
Authors: Palmer D; Wadsworth Center, New York Department of Health, Division of Infectious Disease, Albany, New York, United States of America., Shemshadian A; Department of Biomedical Sciences, University of Albany, Albany, New York, United States of America., Berman K; Wadsworth Center, New York Department of Health, Division of Infectious Disease, Albany, New York, United States of America., Nobles A; Department of Biomedical Sciences, University of Albany, Albany, New York, United States of America., Willsey GG; Wadsworth Center, New York Department of Health, Division of Infectious Disease, Albany, New York, United States of America., Piazza CL; Wadsworth Center, New York Department of Health, Division of Infectious Disease, Albany, New York, United States of America., Freeman-Gallant G; Wadsworth Center, New York Department of Health, Division of Infectious Disease, Albany, New York, United States of America., Rudolph MJ; New York Structural Biology Center, New York, New York, United States of America., Bourgeois J; Deparrment of Microbiology, Tufts University, Boston, Massachusetts, United States of America., Hu L; Deparrment of Microbiology, Tufts University, Boston, Massachusetts, United States of America., Vance DJ; Wadsworth Center, New York Department of Health, Division of Infectious Disease, Albany, New York, United States of America.; Department of Biomedical Sciences, University of Albany, Albany, New York, United States of America., Mantis NJ; Wadsworth Center, New York Department of Health, Division of Infectious Disease, Albany, New York, United States of America.; Department of Biomedical Sciences, University of Albany, Albany, New York, United States of America.
Source: PloS one [PLoS One] 2026 Mar 12; Vol. 21 (3), pp. e0339749. Date of Electronic Publication: 2026 Mar 12 (Print Publication: 2026).
Publication Type: Journal Article
Journal Info: Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet ISSN: 1932-6203 (Electronic) Linking ISSN: 19326203 NLM ISO Abbreviation: PLoS One Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: An Fc-silent OspA monoclonal antibody passively protects mice from tick and intradermal Borrelia burgdorferi challenge.
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