Pleomorphic rhabdomyosarcoma, outcomes of patients with advanced disease treated with systemic agents: Retrospective study from the global pushing ultra-rare sarcomas towards hope (PUSH) consortium.

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Title: Pleomorphic rhabdomyosarcoma, outcomes of patients with advanced disease treated with systemic agents: Retrospective study from the global pushing ultra-rare sarcomas towards hope (PUSH) consortium.
Authors: Baldi GG; Department of Medical Oncology, Hospital of Prato, Azienda USL Toscana Centro, Prato, Italy., Giani C; Department of Medical Oncology, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy., Ljevar S; Unit of Biostatistics for Clinical Research, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy., Denu RA; Department of Sarcoma Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA., Napolitano A; Department of Medical Oncology, The Royal Marsden NHS Foundation Trust and Institute of Cancer Research, London, UK., Han I; Department of Orthopaedic Surgery, Seoul National University Hospital, Seoul, South Korea., Brunello A; Department of Oncology, Medical Oncology 1 Unit, Istituto Oncologico Veneto IOV - IRCCS, Padua, Italy., Bhadri V; Department of Medical Oncology, Chris O'Brien Lifehouse, Sydney, Australia., Sebio A; Department of Medical Oncology, Santa Creu i Sant Pau Hospital/IR Sant Pau, Barcelona, Spain., Andelkovic V; Department of Medical Oncology, Princess Alexandra Hospital, Brisbane, Australia., Campos F; Department of Medical Oncology, A.C.Camargo Cancer Center, São Paulo, Brazil., Scanferla R; Department of Orthopedics Oncology and Reconstructive Surgery, AOU Careggi, Florence, Italy., Abreu MH; Department of Medical Oncology, Portuguese Institute of Oncology, Porto, Portugal., Desar IME; Department of Medical Oncology, Radboud University Medical Centre, Nijmegen, the Netherlands., Ogura K; Department of Musculoskeletal Oncology and Rehabilitation Medicine, National Cancer Center Hospital, Tokyo, Japan., Wong DD; Department of Anatomical Pathology, PathWest, Sir Charles Gairdner Hospital, Perth, Australia., Bae S; Department of Medical Oncology, Peter MacCallum Cancer Centre, Melbourne, VIC, Australia., Bakhshi S; Department of Medical Oncology, India Institute of Medical Sciences, New Delhi, India., Lefler DS; Department of Hematology-Oncology, University of Pennsylvania, Philadelphia, USA., Marquina G; Department of Medical Oncology, Hospital Clinico San Carlos, School of Medicine, UCM, IdISSC, EURACAN referral centre, Madrid, Spain., Mazzocca A; Department of Medical Oncology, Fondazione Policlinico Universitario Campus Bio-Medico, Roma, Italy., Nakazawa MS; Department of Sarcoma Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA., Thway K; Department of Medical Oncology, The Royal Marsden NHS Foundation Trust and Institute of Cancer Research, London, UK., Kim HS; Department of Orthopaedic Surgery, Seoul National University Hospital, Seoul, South Korea., Chiusole B; Department of Oncology, Medical Oncology 1 Unit, Istituto Oncologico Veneto IOV - IRCCS, Padua, Italy., Connolly EA; Department of Medical Oncology, Chris O'Brien Lifehouse, Sydney, Australia., Terés R; Department of Medical Oncology, Santa Creu i Sant Pau Hospital/IR Sant Pau, Barcelona, Spain., Antonescu C; Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, USA., Bellan E; Department of Integrated Diagnostics, Azienda Ospedale-Università Padova, Padova, Italy., V M G Bovée J; Department of Pathology, Leiden University Medical Center, Leiden, the Netherlands., Davis JL; Department of Pathology, Indiana University School of Medicine, Indianapolis, USA., P Dei Tos A; Department of Integrated Diagnostics, Azienda Ospedale-Università Padova, Padova, Italy., Di Blasi E; Department of Pathology, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy., Lazar AJ; Departments of Pathology & Genomic Medicine, The University of Texas MD Anderson Cancer Center, Houston, USA., Sbaraglia M; Department of Integrated Diagnostics, Azienda Ospedale-Università Padova, Padova, Italy., Schaefer IM; Department of Pathology, Harvard Medical School, Brigham and Women's Hospital, Boston, USA., Taverna S; Technology Transfer Office, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy., Gronchi A; Department of Sarcoma Surgery, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy., Miceli R; Unit of Biostatistics for Clinical Research, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy., Chen TW; Department of Oncology, National Taiwan University Hospital, Taipei, Taiwan., Stacchiotti S; Department of Medical Oncology, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy. Electronic address: silvia.stacchiotti@istitutotumori.mi.it.
Source: European journal of cancer (Oxford, England : 1990) [Eur J Cancer] 2026 May 02; Vol. 238, pp. 116666. Date of Electronic Publication: 2026 Mar 08.
Publication Type: Journal Article; Multicenter Study
Journal Info: Publisher: Elsevier Science Ltd Country of Publication: England NLM ID: 9005373 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-0852 (Electronic) Linking ISSN: 09598049 NLM ISO Abbreviation: Eur J Cancer Subsets: MEDLINE
Database: MEDLINE Ultimate
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PubType: Academic Journal
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  Data: Pleomorphic rhabdomyosarcoma, outcomes of patients with advanced disease treated with systemic agents: Retrospective study from the global pushing ultra-rare sarcomas towards hope (PUSH) consortium.
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  Data: <searchLink fieldCode="AU" term="%22Baldi+GG%22">Baldi GG</searchLink>; Department of Medical Oncology, Hospital of Prato, Azienda USL Toscana Centro, Prato, Italy.<br /><searchLink fieldCode="AU" term="%22Giani+C%22">Giani C</searchLink>; Department of Medical Oncology, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Ljevar+S%22">Ljevar S</searchLink>; Unit of Biostatistics for Clinical Research, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Denu+RA%22">Denu RA</searchLink>; Department of Sarcoma Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.<br /><searchLink fieldCode="AU" term="%22Napolitano+A%22">Napolitano A</searchLink>; Department of Medical Oncology, The Royal Marsden NHS Foundation Trust and Institute of Cancer Research, London, UK.<br /><searchLink fieldCode="AU" term="%22Han+I%22">Han I</searchLink>; Department of Orthopaedic Surgery, Seoul National University Hospital, Seoul, South Korea.<br /><searchLink fieldCode="AU" term="%22Brunello+A%22">Brunello A</searchLink>; Department of Oncology, Medical Oncology 1 Unit, Istituto Oncologico Veneto IOV - IRCCS, Padua, Italy.<br /><searchLink fieldCode="AU" term="%22Bhadri+V%22">Bhadri V</searchLink>; Department of Medical Oncology, Chris O'Brien Lifehouse, Sydney, Australia.<br /><searchLink fieldCode="AU" term="%22Sebio+A%22">Sebio A</searchLink>; Department of Medical Oncology, Santa Creu i Sant Pau Hospital/IR Sant Pau, Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22Andelkovic+V%22">Andelkovic V</searchLink>; Department of Medical Oncology, Princess Alexandra Hospital, Brisbane, Australia.<br /><searchLink fieldCode="AU" term="%22Campos+F%22">Campos F</searchLink>; Department of Medical Oncology, A.C.Camargo Cancer Center, São Paulo, Brazil.<br /><searchLink fieldCode="AU" term="%22Scanferla+R%22">Scanferla R</searchLink>; Department of Orthopedics Oncology and Reconstructive Surgery, AOU Careggi, Florence, Italy.<br /><searchLink fieldCode="AU" term="%22Abreu+MH%22">Abreu MH</searchLink>; Department of Medical Oncology, Portuguese Institute of Oncology, Porto, Portugal.<br /><searchLink fieldCode="AU" term="%22Desar+IME%22">Desar IME</searchLink>; Department of Medical Oncology, Radboud University Medical Centre, Nijmegen, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Ogura+K%22">Ogura K</searchLink>; Department of Musculoskeletal Oncology and Rehabilitation Medicine, National Cancer Center Hospital, Tokyo, Japan.<br /><searchLink fieldCode="AU" term="%22Wong+DD%22">Wong DD</searchLink>; Department of Anatomical Pathology, PathWest, Sir Charles Gairdner Hospital, Perth, Australia.<br /><searchLink fieldCode="AU" term="%22Bae+S%22">Bae S</searchLink>; Department of Medical Oncology, Peter MacCallum Cancer Centre, Melbourne, VIC, Australia.<br /><searchLink fieldCode="AU" term="%22Bakhshi+S%22">Bakhshi S</searchLink>; Department of Medical Oncology, India Institute of Medical Sciences, New Delhi, India.<br /><searchLink fieldCode="AU" term="%22Lefler+DS%22">Lefler DS</searchLink>; Department of Hematology-Oncology, University of Pennsylvania, Philadelphia, USA.<br /><searchLink fieldCode="AU" term="%22Marquina+G%22">Marquina G</searchLink>; Department of Medical Oncology, Hospital Clinico San Carlos, School of Medicine, UCM, IdISSC, EURACAN referral centre, Madrid, Spain.<br /><searchLink fieldCode="AU" term="%22Mazzocca+A%22">Mazzocca A</searchLink>; Department of Medical Oncology, Fondazione Policlinico Universitario Campus Bio-Medico, Roma, Italy.<br /><searchLink fieldCode="AU" term="%22Nakazawa+MS%22">Nakazawa MS</searchLink>; Department of Sarcoma Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.<br /><searchLink fieldCode="AU" term="%22Thway+K%22">Thway K</searchLink>; Department of Medical Oncology, The Royal Marsden NHS Foundation Trust and Institute of Cancer Research, London, UK.<br /><searchLink fieldCode="AU" term="%22Kim+HS%22">Kim HS</searchLink>; Department of Orthopaedic Surgery, Seoul National University Hospital, Seoul, South Korea.<br /><searchLink fieldCode="AU" term="%22Chiusole+B%22">Chiusole B</searchLink>; Department of Oncology, Medical Oncology 1 Unit, Istituto Oncologico Veneto IOV - IRCCS, Padua, Italy.<br /><searchLink fieldCode="AU" term="%22Connolly+EA%22">Connolly EA</searchLink>; Department of Medical Oncology, Chris O'Brien Lifehouse, Sydney, Australia.<br /><searchLink fieldCode="AU" term="%22Terés+R%22">Terés R</searchLink>; Department of Medical Oncology, Santa Creu i Sant Pau Hospital/IR Sant Pau, Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22Antonescu+C%22">Antonescu C</searchLink>; Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, USA.<br /><searchLink fieldCode="AU" term="%22Bellan+E%22">Bellan E</searchLink>; Department of Integrated Diagnostics, Azienda Ospedale-Università Padova, Padova, Italy.<br /><searchLink fieldCode="AU" term="%22V+M+G+Bovée+J%22">V M G Bovée J</searchLink>; Department of Pathology, Leiden University Medical Center, Leiden, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Davis+JL%22">Davis JL</searchLink>; Department of Pathology, Indiana University School of Medicine, Indianapolis, USA.<br /><searchLink fieldCode="AU" term="%22P+Dei+Tos+A%22">P Dei Tos A</searchLink>; Department of Integrated Diagnostics, Azienda Ospedale-Università Padova, Padova, Italy.<br /><searchLink fieldCode="AU" term="%22Di+Blasi+E%22">Di Blasi E</searchLink>; Department of Pathology, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Lazar+AJ%22">Lazar AJ</searchLink>; Departments of Pathology & Genomic Medicine, The University of Texas MD Anderson Cancer Center, Houston, USA.<br /><searchLink fieldCode="AU" term="%22Sbaraglia+M%22">Sbaraglia M</searchLink>; Department of Integrated Diagnostics, Azienda Ospedale-Università Padova, Padova, Italy.<br /><searchLink fieldCode="AU" term="%22Schaefer+IM%22">Schaefer IM</searchLink>; Department of Pathology, Harvard Medical School, Brigham and Women's Hospital, Boston, USA.<br /><searchLink fieldCode="AU" term="%22Taverna+S%22">Taverna S</searchLink>; Technology Transfer Office, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Gronchi+A%22">Gronchi A</searchLink>; Department of Sarcoma Surgery, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Miceli+R%22">Miceli R</searchLink>; Unit of Biostatistics for Clinical Research, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Chen+TW%22">Chen TW</searchLink>; Department of Oncology, National Taiwan University Hospital, Taipei, Taiwan.<br /><searchLink fieldCode="AU" term="%22Stacchiotti+S%22">Stacchiotti S</searchLink>; Department of Medical Oncology, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy. Electronic address: silvia.stacchiotti@istitutotumori.mi.it.
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