Neoadjuvant transarterial chemoembolization with tyrosine kinase and immune checkpoint inhibitors improves survival from resectable hepatocellular carcinoma in a multicenter, retrospective study (GUIDANCE002).
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| Title: | Neoadjuvant transarterial chemoembolization with tyrosine kinase and immune checkpoint inhibitors improves survival from resectable hepatocellular carcinoma in a multicenter, retrospective study (GUIDANCE002). |
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| Authors: | Yang DL; Department of Hepatobiliary Surgery, Guangxi Medical University Cancer Hospital, Nanning, China., Qin C; Department of Hepatobiliary Surgery, Liuzhou People's Hospital, Liuzhou, China., Peng N; Department of Hepatobiliary Surgery, First Affiliated Hospital of Guangxi Medical University, Nanning, China., Liu SP; Department of Hepatobiliary and Pancreatic Surgery, Eighth Affiliated Hospital of Guangxi Medical University, Guigang, China., Yu YQ; Department of Hepatobiliary and Pancreatic Surgery, Affiliated Hospital of Guilin Medical University, Guilin, China., Nong JL; Department of Hepatobiliary Surgery, Hengzhou City People's Hospital, Hengzhou, China., Zeng FJ; Department of Hepatobiliary Surgery, Wuzhou Red Cross Hospital, Wuzhou, China., Su Z; Department of Hepatobiliary Pancreatic Surgery, First People's Hospital of Nanning, Nanning, China., Yang YY; Department of Hepatobiliary, Pancreatic and Spleen Surgery, People's Hospital of Guangxi Zhuang Autonomous Region, Guangxi Academy of Medical Sciences, Nanning, China., Yang FQ; Department of Hepatobiliary and Pancreatic Surgery, First People's Hospital of Yulin, Yulin, China., Li MJ; Department of Hepatobiliary Pancreatic Surgery, Guilin People's Hospital, Guilin, China., Wu MS; Department of Oncology, People's Hospital of Beiliu, Beiliu, China., Wang XY; Department of Hepatobiliary and Pancreatic Surgery, Second Affiliated Hospital of Guilin Medical University, Guilin, China., Liang YR; Department of Hepatobiliary and Pancreatic Surgery, First People's Hospital of Qinzhou, Qinzhou, China., Li FX; Department of Hepatobiliary, Pancreatic and Spleen Surgery, People's Hospital of Hezhou, Hezhou, China., Chen SC; Department of Hepatobiliary Surgery, Wuzhou People's Hospital, Wuzhou, China., Lai YC; Department of Hepatobiliary Gland Surgery, Beihai People's Hospital, Beihai, China., Pang QQ; Department of Oncology, Liuzhou Workers Hospital, Liuzhou, China., Zhong TM; Department of Hepatobiliary Surgery, Baise People's Hospital, Baise, China., Yan YH; Department of General Surgery, Second Affiliated Hospital of Guangxi Medical University, Nanning, China., Zhang YY; Department of Hepatobiliary Surgery, Liuzhou People's Hospital, Liuzhou, China., Ye L; Department of Hepatobiliary and Pancreatic Surgery, Affiliated Hospital of Guilin Medical University, Guilin, China., Dong XF; Department of Hepatobiliary, Pancreatic and Spleen Surgery, People's Hospital of Guangxi Zhuang Autonomous Region, Guangxi Academy of Medical Sciences, Nanning, China., Li WF; Department of Hepatobiliary and Pancreatic Surgery, First People's Hospital of Yulin, Yulin, China., Liu J; Department of Hepatobiliary Pancreatic Surgery, Guilin People's Hospital, Guilin, China., Yao HB; Department of Hepatobiliary and Pancreatic Surgery, Second Affiliated Hospital of Guilin Medical University, Guilin, China., Wu PS; Department of Hepatobiliary and Pancreatic Surgery, First People's Hospital of Qinzhou, Qinzhou, China., Mao XS; Department of Hepatobiliary, Pancreatic and Spleen Surgery, People's Hospital of Hezhou, Hezhou, China., Ou JJ; Department of Hepatobiliary Surgery, Wuzhou People's Hospital, Wuzhou, China., Chen YZ; Department of Hepatobiliary Gland Surgery, Beihai People's Hospital, Beihai, China., Wang GD; Department of Oncology, Liuzhou Workers Hospital, Liuzhou, China., Chen K; Department of General Surgery, Second Affiliated Hospital of Guangxi Medical University, Nanning, China., Deng ZJ; Department of Hepatobiliary Surgery, Guangxi Medical University Cancer Hospital, Nanning, China., Su JY; Department of Hepatobiliary Surgery, Guangxi Medical University Cancer Hospital, Nanning, China., Qiu GG; Department of Hepatobiliary Surgery, Guangxi Medical University Cancer Hospital, Nanning, China., Liu ZD; Department of Hepatobiliary Surgery, Guangxi Medical University Cancer Hospital, Nanning, China., Wang JM; Department of Hepatobiliary Surgery, Guangxi Medical University Cancer Hospital, Nanning, China., Zhang Y; Department of Hepatobiliary Surgery, Guangxi Medical University Cancer Hospital, Nanning, China., Liang XM; Department of Hepatobiliary Surgery, Guangxi Medical University Cancer Hospital, Nanning, China., Xiang BD; Department of Hepatobiliary Surgery, Guangxi Medical University Cancer Hospital, Nanning, China., Ma L; Department of Hepatobiliary Surgery, Guangxi Medical University Cancer Hospital, Nanning, China., Zhong JH; Department of Hepatobiliary Surgery, Guangxi Medical University Cancer Hospital, Nanning, China. zhongjianhong@gxmu.edu.cn. |
| Corporate Authors: | GUIDANCE investigators |
| Source: | Communications medicine [Commun Med (Lond)] 2026 Mar 12; Vol. 6 (1). Date of Electronic Publication: 2026 Mar 12. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Nature Portfolio Country of Publication: England NLM ID: 9918250414506676 Publication Model: Electronic Cited Medium: Internet ISSN: 2730-664X (Electronic) Linking ISSN: 2730664X NLM ISO Abbreviation: Commun Med (Lond) Subsets: PubMed not MEDLINE |
| Database: | MEDLINE Ultimate |
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| Header | DbId: mdl DbLabel: MEDLINE Ultimate An: 41820518 AccessLevel: 2 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: Neoadjuvant transarterial chemoembolization with tyrosine kinase and immune checkpoint inhibitors improves survival from resectable hepatocellular carcinoma in a multicenter, retrospective study (GUIDANCE002). – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AU" term="%22Yang+DL%22">Yang DL</searchLink>; Department of Hepatobiliary Surgery, Guangxi Medical University Cancer Hospital, Nanning, China.<br /><searchLink fieldCode="AU" term="%22Qin+C%22">Qin C</searchLink>; Department of Hepatobiliary Surgery, Liuzhou People's Hospital, Liuzhou, China.<br /><searchLink fieldCode="AU" term="%22Peng+N%22">Peng N</searchLink>; Department of Hepatobiliary Surgery, First Affiliated Hospital of Guangxi Medical University, Nanning, China.<br /><searchLink fieldCode="AU" term="%22Liu+SP%22">Liu SP</searchLink>; Department of Hepatobiliary and Pancreatic Surgery, Eighth Affiliated Hospital of Guangxi Medical University, Guigang, China.<br /><searchLink fieldCode="AU" term="%22Yu+YQ%22">Yu YQ</searchLink>; Department of Hepatobiliary and Pancreatic Surgery, Affiliated Hospital of Guilin Medical University, Guilin, China.<br /><searchLink fieldCode="AU" term="%22Nong+JL%22">Nong JL</searchLink>; Department of Hepatobiliary Surgery, Hengzhou City People's Hospital, Hengzhou, China.<br /><searchLink fieldCode="AU" term="%22Zeng+FJ%22">Zeng FJ</searchLink>; Department of Hepatobiliary Surgery, Wuzhou Red Cross Hospital, Wuzhou, China.<br /><searchLink fieldCode="AU" term="%22Su+Z%22">Su Z</searchLink>; Department of Hepatobiliary Pancreatic Surgery, First People's Hospital of Nanning, Nanning, China.<br /><searchLink fieldCode="AU" term="%22Yang+YY%22">Yang YY</searchLink>; Department of Hepatobiliary, Pancreatic and Spleen Surgery, People's Hospital of Guangxi Zhuang Autonomous Region, Guangxi Academy of Medical Sciences, Nanning, China.<br /><searchLink fieldCode="AU" term="%22Yang+FQ%22">Yang FQ</searchLink>; Department of Hepatobiliary and Pancreatic Surgery, First People's Hospital of Yulin, Yulin, China.<br /><searchLink fieldCode="AU" term="%22Li+MJ%22">Li MJ</searchLink>; Department of Hepatobiliary Pancreatic Surgery, Guilin People's Hospital, Guilin, China.<br /><searchLink fieldCode="AU" term="%22Wu+MS%22">Wu MS</searchLink>; Department of Oncology, People's Hospital of Beiliu, Beiliu, China.<br /><searchLink fieldCode="AU" term="%22Wang+XY%22">Wang XY</searchLink>; Department of Hepatobiliary and Pancreatic Surgery, Second Affiliated Hospital of Guilin Medical University, Guilin, China.<br /><searchLink fieldCode="AU" term="%22Liang+YR%22">Liang YR</searchLink>; Department of Hepatobiliary and Pancreatic Surgery, First People's Hospital of Qinzhou, Qinzhou, China.<br /><searchLink fieldCode="AU" term="%22Li+FX%22">Li FX</searchLink>; Department of Hepatobiliary, Pancreatic and Spleen Surgery, People's Hospital of Hezhou, Hezhou, China.<br /><searchLink fieldCode="AU" term="%22Chen+SC%22">Chen SC</searchLink>; Department of Hepatobiliary Surgery, Wuzhou People's Hospital, Wuzhou, China.<br /><searchLink fieldCode="AU" term="%22Lai+YC%22">Lai YC</searchLink>; Department of Hepatobiliary Gland Surgery, Beihai People's Hospital, Beihai, China.<br /><searchLink fieldCode="AU" term="%22Pang+QQ%22">Pang QQ</searchLink>; Department of Oncology, Liuzhou Workers Hospital, Liuzhou, China.<br /><searchLink fieldCode="AU" term="%22Zhong+TM%22">Zhong TM</searchLink>; Department of Hepatobiliary Surgery, Baise People's Hospital, Baise, China.<br /><searchLink fieldCode="AU" term="%22Yan+YH%22">Yan YH</searchLink>; Department of General Surgery, Second Affiliated Hospital of Guangxi Medical University, Nanning, China.<br /><searchLink fieldCode="AU" term="%22Zhang+YY%22">Zhang YY</searchLink>; Department of Hepatobiliary Surgery, Liuzhou People's Hospital, Liuzhou, China.<br /><searchLink fieldCode="AU" term="%22Ye+L%22">Ye L</searchLink>; Department of Hepatobiliary and Pancreatic Surgery, Affiliated Hospital of Guilin Medical University, Guilin, China.<br /><searchLink fieldCode="AU" term="%22Dong+XF%22">Dong XF</searchLink>; Department of Hepatobiliary, Pancreatic and Spleen Surgery, People's Hospital of Guangxi Zhuang Autonomous Region, Guangxi Academy of Medical Sciences, Nanning, China.<br /><searchLink fieldCode="AU" term="%22Li+WF%22">Li WF</searchLink>; Department of Hepatobiliary and Pancreatic Surgery, First People's Hospital of Yulin, Yulin, China.<br /><searchLink fieldCode="AU" term="%22Liu+J%22">Liu J</searchLink>; Department of Hepatobiliary Pancreatic Surgery, Guilin People's Hospital, Guilin, China.<br /><searchLink fieldCode="AU" term="%22Yao+HB%22">Yao HB</searchLink>; Department of Hepatobiliary and Pancreatic Surgery, Second Affiliated Hospital of Guilin Medical University, Guilin, China.<br /><searchLink fieldCode="AU" term="%22Wu+PS%22">Wu PS</searchLink>; Department of Hepatobiliary and Pancreatic Surgery, First People's Hospital of Qinzhou, Qinzhou, China.<br /><searchLink fieldCode="AU" term="%22Mao+XS%22">Mao XS</searchLink>; Department of Hepatobiliary, Pancreatic and Spleen Surgery, People's Hospital of Hezhou, Hezhou, China.<br /><searchLink fieldCode="AU" term="%22Ou+JJ%22">Ou JJ</searchLink>; Department of Hepatobiliary Surgery, Wuzhou People's Hospital, Wuzhou, China.<br /><searchLink fieldCode="AU" term="%22Chen+YZ%22">Chen YZ</searchLink>; Department of Hepatobiliary Gland Surgery, Beihai People's Hospital, Beihai, China.<br /><searchLink fieldCode="AU" term="%22Wang+GD%22">Wang GD</searchLink>; Department of Oncology, Liuzhou Workers Hospital, Liuzhou, China.<br /><searchLink fieldCode="AU" term="%22Chen+K%22">Chen K</searchLink>; Department of General Surgery, Second Affiliated Hospital of Guangxi Medical University, Nanning, China.<br /><searchLink fieldCode="AU" term="%22Deng+ZJ%22">Deng ZJ</searchLink>; Department of Hepatobiliary Surgery, Guangxi Medical University Cancer Hospital, Nanning, China.<br /><searchLink fieldCode="AU" term="%22Su+JY%22">Su JY</searchLink>; Department of Hepatobiliary Surgery, Guangxi Medical University Cancer Hospital, Nanning, China.<br /><searchLink fieldCode="AU" term="%22Qiu+GG%22">Qiu GG</searchLink>; Department of Hepatobiliary Surgery, Guangxi Medical University Cancer Hospital, Nanning, China.<br /><searchLink fieldCode="AU" term="%22Liu+ZD%22">Liu ZD</searchLink>; Department of Hepatobiliary Surgery, Guangxi Medical University Cancer Hospital, Nanning, China.<br /><searchLink fieldCode="AU" term="%22Wang+JM%22">Wang JM</searchLink>; Department of Hepatobiliary Surgery, Guangxi Medical University Cancer Hospital, Nanning, China.<br /><searchLink fieldCode="AU" term="%22Zhang+Y%22">Zhang Y</searchLink>; Department of Hepatobiliary Surgery, Guangxi Medical University Cancer Hospital, Nanning, China.<br /><searchLink fieldCode="AU" term="%22Liang+XM%22">Liang XM</searchLink>; Department of Hepatobiliary Surgery, Guangxi Medical University Cancer Hospital, Nanning, China.<br /><searchLink fieldCode="AU" term="%22Xiang+BD%22">Xiang BD</searchLink>; Department of Hepatobiliary Surgery, Guangxi Medical University Cancer Hospital, Nanning, China.<br /><searchLink fieldCode="AU" term="%22Ma+L%22">Ma L</searchLink>; Department of Hepatobiliary Surgery, Guangxi Medical University Cancer Hospital, Nanning, China.<br /><searchLink fieldCode="AU" term="%22Zhong+JH%22">Zhong JH</searchLink>; Department of Hepatobiliary Surgery, Guangxi Medical University Cancer Hospital, Nanning, China. zhongjianhong@gxmu.edu.cn. – Name: AuthorCorporate Label: Corporate Authors Group: Au Data: <searchLink fieldCode="CA" term="%22GUIDANCE+investigators%22">GUIDANCE investigators</searchLink> – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%229918250414506676%22">Communications medicine</searchLink> [Commun Med (Lond)] 2026 Mar 12; Vol. 6 (1). <i>Date of Electronic Publication: </i>2026 Mar 12. – Name: TypePub Label: Publication Type Group: TypPub Data: Journal Article – Name: TitleSource Label: Journal Info Group: Src Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Nature+Portfolio%22">Nature Portfolio </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>9918250414506676 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>2730-664X (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%222730664X%22">2730664X </searchLink><i>NLM ISO Abbreviation: </i>Commun Med (Lond) <i>Subsets: </i>PubMed not MEDLINE |
| PLink | https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=41820518 |
| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1038/s43856-025-01303-w Languages: – Code: eng Text: English Titles: – TitleFull: Neoadjuvant transarterial chemoembolization with tyrosine kinase and immune checkpoint inhibitors improves survival from resectable hepatocellular carcinoma in a multicenter, retrospective study (GUIDANCE002). Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Yang DL – PersonEntity: Name: NameFull: Qin C – PersonEntity: Name: NameFull: Peng N – PersonEntity: Name: NameFull: Liu SP – PersonEntity: Name: NameFull: Yu YQ – PersonEntity: Name: NameFull: Nong JL – PersonEntity: Name: NameFull: Zeng FJ – PersonEntity: Name: NameFull: Su Z – PersonEntity: Name: NameFull: Yang YY – PersonEntity: Name: NameFull: Yang FQ – PersonEntity: Name: NameFull: Li MJ – PersonEntity: Name: NameFull: Wu MS – PersonEntity: Name: NameFull: Wang XY – PersonEntity: Name: NameFull: Liang YR – PersonEntity: Name: NameFull: Li FX – PersonEntity: Name: NameFull: Chen SC – PersonEntity: Name: NameFull: Lai YC – PersonEntity: Name: NameFull: Pang QQ – PersonEntity: Name: NameFull: Zhong TM – PersonEntity: Name: NameFull: Yan YH – PersonEntity: Name: NameFull: Zhang YY – PersonEntity: Name: NameFull: Ye L – PersonEntity: Name: NameFull: Dong XF – PersonEntity: Name: NameFull: Li WF – PersonEntity: Name: NameFull: Liu J – PersonEntity: Name: NameFull: Yao HB – PersonEntity: Name: NameFull: Wu PS – PersonEntity: Name: NameFull: Mao XS – PersonEntity: Name: NameFull: Ou JJ – PersonEntity: Name: NameFull: Chen YZ – PersonEntity: Name: NameFull: Wang GD – PersonEntity: Name: NameFull: Chen K – PersonEntity: Name: NameFull: Deng ZJ – PersonEntity: Name: NameFull: Su JY – PersonEntity: Name: NameFull: Qiu GG – PersonEntity: Name: NameFull: Liu ZD – PersonEntity: Name: NameFull: Wang JM – PersonEntity: Name: NameFull: Zhang Y – PersonEntity: Name: NameFull: Liang XM – PersonEntity: Name: NameFull: Xiang BD – PersonEntity: Name: NameFull: Ma L – PersonEntity: Name: NameFull: Zhong JH IsPartOfRelationships: – BibEntity: Dates: – D: 12 M: 03 Text: 2026 Mar 12 Type: published Y: 2026 Identifiers: – Type: issn-electronic Value: 2730-664X Numbering: – Type: volume Value: 6 – Type: issue Value: 1 Titles: – TitleFull: Communications medicine Type: main |
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