Connectome-seq: high-throughput mapping of neuronal connectivity at single-synapse resolution via barcode sequencing.

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Bibliographic Details
Title: Connectome-seq: high-throughput mapping of neuronal connectivity at single-synapse resolution via barcode sequencing.
Authors: Chen D; Department of Cell and Developmental Biology, University of Illinois Urbana-Champaign, Urbana, IL, USA., Isakova A; Department of Bioengineering, Stanford University, Stanford, CA, USA., Wan Z; Department of Cell and Developmental Biology, University of Illinois Urbana-Champaign, Urbana, IL, USA.; Neuroscience Program, University of Illinois Urbana-Champaign, Urbana, IL, USA., Wagner MJ; National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD, USA., Wu Y; Department of Biology and Howard Hughes Medical Institute, Stanford University, Stanford, CA, USA., Zhao BS; Department of Cell and Developmental Biology, University of Illinois Urbana-Champaign, Urbana, IL, USA. zbx@illinois.edu.; Neuroscience Program, University of Illinois Urbana-Champaign, Urbana, IL, USA. zbx@illinois.edu.; Carl R. Woese Institute for Genomic Biology, University of Illinois Urbana-Champaign, Urbana, IL, USA. zbx@illinois.edu.; Cancer Center at Illinois, University of Illinois Urbana-Champaign, Urbana, IL, USA. zbx@illinois.edu.
Source: Nature methods [Nat Methods] 2026 Apr; Vol. 23 (4), pp. 823-838. Date of Electronic Publication: 2026 Mar 12.
Publication Type: Journal Article
Journal Info: Publisher: Nature Pub. Group Country of Publication: United States NLM ID: 101215604 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1548-7105 (Electronic) Linking ISSN: 15487091 NLM ISO Abbreviation: Nat Methods Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1548-7105
DOI:10.1038/s41592-026-03026-9