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Non-linear associations of amyloid-β with resting-state functional networks and their cognitive relevance in a large community-based cohort of cognitively normal older adults.

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Title: Non-linear associations of amyloid-β with resting-state functional networks and their cognitive relevance in a large community-based cohort of cognitively normal older adults.
Authors: Wu J; Department of Neurology, Emory University, 6 Executive Park Dr NE, Atlanta, GA, 30329, USA.; Department of Radiology and Imaging Sciences, Emory University, 1364 Clifton Rd NE, Atlanta, GA, 30322, USA., Risk BB; Department of Biostatistics and Bioinformatics, Emory University, Atlanta, GA, USA., James TA; Department of Neurology, Emory University, 6 Executive Park Dr NE, Atlanta, GA, 30329, USA., Seyfried NT; Department of Neurology, Emory University, 6 Executive Park Dr NE, Atlanta, GA, 30329, USA.; Department of Biochemistry, Emory University, Atlanta, GA, USA., Loring DW; Department of Neurology, Emory University, 6 Executive Park Dr NE, Atlanta, GA, 30329, USA., Goldstein FC; Department of Neurology, Emory University, 6 Executive Park Dr NE, Atlanta, GA, 30329, USA., Levey AI; Department of Neurology, Emory University, 6 Executive Park Dr NE, Atlanta, GA, 30329, USA., Lah JJ; Department of Neurology, Emory University, 6 Executive Park Dr NE, Atlanta, GA, 30329, USA. jlah@emory.edu., Qiu D; Department of Radiology and Imaging Sciences, Emory University, 1364 Clifton Rd NE, Atlanta, GA, 30322, USA. dqiu3@emory.edu.; Joint Department of Biomedical Engineering, Emory University, Georgia Institute of Technology, Atlanta, GA, USA. dqiu3@emory.edu.
Source: Alzheimer's research & therapy [Alzheimers Res Ther] 2026 Mar 12; Vol. 18 (1). Date of Electronic Publication: 2026 Mar 12.
Publication Type: Journal Article; Research Support, N.I.H., Extramural
Journal Info: Publisher: BioMed Central Ltd Country of Publication: England NLM ID: 101511643 Publication Model: Electronic Cited Medium: Internet ISSN: 1758-9193 (Electronic) NLM ISO Abbreviation: Alzheimers Res Ther Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Non-linear associations of amyloid-β with resting-state functional networks and their cognitive relevance in a large community-based cohort of cognitively normal older adults.
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  Data: <searchLink fieldCode="AU" term="%22Wu+J%22">Wu J</searchLink>; Department of Neurology, Emory University, 6 Executive Park Dr NE, Atlanta, GA, 30329, USA.; Department of Radiology and Imaging Sciences, Emory University, 1364 Clifton Rd NE, Atlanta, GA, 30322, USA.<br /><searchLink fieldCode="AU" term="%22Risk+BB%22">Risk BB</searchLink>; Department of Biostatistics and Bioinformatics, Emory University, Atlanta, GA, USA.<br /><searchLink fieldCode="AU" term="%22James+TA%22">James TA</searchLink>; Department of Neurology, Emory University, 6 Executive Park Dr NE, Atlanta, GA, 30329, USA.<br /><searchLink fieldCode="AU" term="%22Seyfried+NT%22">Seyfried NT</searchLink>; Department of Neurology, Emory University, 6 Executive Park Dr NE, Atlanta, GA, 30329, USA.; Department of Biochemistry, Emory University, Atlanta, GA, USA.<br /><searchLink fieldCode="AU" term="%22Loring+DW%22">Loring DW</searchLink>; Department of Neurology, Emory University, 6 Executive Park Dr NE, Atlanta, GA, 30329, USA.<br /><searchLink fieldCode="AU" term="%22Goldstein+FC%22">Goldstein FC</searchLink>; Department of Neurology, Emory University, 6 Executive Park Dr NE, Atlanta, GA, 30329, USA.<br /><searchLink fieldCode="AU" term="%22Levey+AI%22">Levey AI</searchLink>; Department of Neurology, Emory University, 6 Executive Park Dr NE, Atlanta, GA, 30329, USA.<br /><searchLink fieldCode="AU" term="%22Lah+JJ%22">Lah JJ</searchLink>; Department of Neurology, Emory University, 6 Executive Park Dr NE, Atlanta, GA, 30329, USA. jlah@emory.edu.<br /><searchLink fieldCode="AU" term="%22Qiu+D%22">Qiu D</searchLink>; Department of Radiology and Imaging Sciences, Emory University, 1364 Clifton Rd NE, Atlanta, GA, 30322, USA. dqiu3@emory.edu.; Joint Department of Biomedical Engineering, Emory University, Georgia Institute of Technology, Atlanta, GA, USA. dqiu3@emory.edu.
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  Data: <searchLink fieldCode="JN" term="%22101511643%22">Alzheimer's research & therapy</searchLink> [Alzheimers Res Ther] 2026 Mar 12; Vol. 18 (1). <i>Date of Electronic Publication: </i>2026 Mar 12.
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  Data: Journal Article; Research Support, N.I.H., Extramural
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22BioMed+Central+Ltd%22">BioMed Central Ltd </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>101511643 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1758-9193 (Electronic) <i>NLM ISO Abbreviation: </i>Alzheimers Res Ther <i>Subsets: </i>MEDLINE
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        Value: 10.1186/s13195-026-01986-w
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      – Code: eng
        Text: English
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      – TitleFull: Non-linear associations of amyloid-β with resting-state functional networks and their cognitive relevance in a large community-based cohort of cognitively normal older adults.
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              Text: 2026 Mar 12
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