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Structure-functionality relationship of collagen-fibrin interpenetrating hydrogels for engineered tumor-stroma models.

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Title: Structure-functionality relationship of collagen-fibrin interpenetrating hydrogels for engineered tumor-stroma models.
Authors: Choi SR; Department of Mechanical Science and Engineering, University of Illinois Urbana-Champaign, Urbana, IL, 61801, USA; Cancer Center at Illinois, University of Illinois Urbana-Champaign, Urbana, IL, 61801, USA., Mellican SM; Department of Mechanical Science and Engineering, University of Illinois Urbana-Champaign, Urbana, IL, 61801, USA., Roberts TJ; Davidson School of Chemical Engineering, Purdue University, West Lafayette, IN, 47907, USA., Kang S; Department of Mechanical Science and Engineering, University of Illinois Urbana-Champaign, Urbana, IL, 61801, USA; Department of Chemical and Biomolecular Engineering, University of Illinois Urbana-Champaign, Urbana, IL, 61801, USA., Elzey BD; Department of Comparative Pathobiology and Purdue Institute for Cancer Research, Purdue University, IN, 47907, USA., Kong H; Cancer Center at Illinois, University of Illinois Urbana-Champaign, Urbana, IL, 61801, USA; Department of Chemical and Biomolecular Engineering, University of Illinois Urbana-Champaign, Urbana, IL, 61801, USA; Chan Zuckerberg Biohub Chicago, Chicago, IL, 60642, USA., Davis CS; Department of Mechanical Engineering, University of Delaware, Newark, DE, 19716, USA., Fishel ML; Department of Pediatrics, Department of Biochemistry, Molecular Biology and Pharmacology, Herman B Wells Center for Pediatric Research and Indiana University Simon Comprehensive Cancer Center, Indiana University School of Medicine, Indianapolis, IN, 46202, USA., Flick MJ; Department of Pathology and Laboratory Medicine and UNC Blood Research Center, University of North Carolina at Chapel Hill, NC, 27599, USA., Wolberg AS; Department of Pathology and Laboratory Medicine and UNC Blood Research Center, University of North Carolina at Chapel Hill, NC, 27599, USA., Han B; Department of Mechanical Science and Engineering, University of Illinois Urbana-Champaign, Urbana, IL, 61801, USA; Cancer Center at Illinois, University of Illinois Urbana-Champaign, Urbana, IL, 61801, USA; Chan Zuckerberg Biohub Chicago, Chicago, IL, 60642, USA; Department of Bioengineering, Materials Research Laboratory, Institute of Genomic Biology and Beckman Institute, University of Illinois Urbana-Champaign, Urbana, IL, 61801, USA. Electronic address: bumsooh@illinois.edu.
Source: Acta biomaterialia [Acta Biomater] 2026 Apr; Vol. 214, pp. 271-284. Date of Electronic Publication: 2026 Mar 11.
Publication Type: Journal Article
Journal Info: Publisher: Elsevier Country of Publication: England NLM ID: 101233144 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1878-7568 (Electronic) Linking ISSN: 17427061 NLM ISO Abbreviation: Acta Biomater Subsets: MEDLINE
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  Data: <searchLink fieldCode="AU" term="%22Choi+SR%22">Choi SR</searchLink>; Department of Mechanical Science and Engineering, University of Illinois Urbana-Champaign, Urbana, IL, 61801, USA; Cancer Center at Illinois, University of Illinois Urbana-Champaign, Urbana, IL, 61801, USA.<br /><searchLink fieldCode="AU" term="%22Mellican+SM%22">Mellican SM</searchLink>; Department of Mechanical Science and Engineering, University of Illinois Urbana-Champaign, Urbana, IL, 61801, USA.<br /><searchLink fieldCode="AU" term="%22Roberts+TJ%22">Roberts TJ</searchLink>; Davidson School of Chemical Engineering, Purdue University, West Lafayette, IN, 47907, USA.<br /><searchLink fieldCode="AU" term="%22Kang+S%22">Kang S</searchLink>; Department of Mechanical Science and Engineering, University of Illinois Urbana-Champaign, Urbana, IL, 61801, USA; Department of Chemical and Biomolecular Engineering, University of Illinois Urbana-Champaign, Urbana, IL, 61801, USA.<br /><searchLink fieldCode="AU" term="%22Elzey+BD%22">Elzey BD</searchLink>; Department of Comparative Pathobiology and Purdue Institute for Cancer Research, Purdue University, IN, 47907, USA.<br /><searchLink fieldCode="AU" term="%22Kong+H%22">Kong H</searchLink>; Cancer Center at Illinois, University of Illinois Urbana-Champaign, Urbana, IL, 61801, USA; Department of Chemical and Biomolecular Engineering, University of Illinois Urbana-Champaign, Urbana, IL, 61801, USA; Chan Zuckerberg Biohub Chicago, Chicago, IL, 60642, USA.<br /><searchLink fieldCode="AU" term="%22Davis+CS%22">Davis CS</searchLink>; Department of Mechanical Engineering, University of Delaware, Newark, DE, 19716, USA.<br /><searchLink fieldCode="AU" term="%22Fishel+ML%22">Fishel ML</searchLink>; Department of Pediatrics, Department of Biochemistry, Molecular Biology and Pharmacology, Herman B Wells Center for Pediatric Research and Indiana University Simon Comprehensive Cancer Center, Indiana University School of Medicine, Indianapolis, IN, 46202, USA.<br /><searchLink fieldCode="AU" term="%22Flick+MJ%22">Flick MJ</searchLink>; Department of Pathology and Laboratory Medicine and UNC Blood Research Center, University of North Carolina at Chapel Hill, NC, 27599, USA.<br /><searchLink fieldCode="AU" term="%22Wolberg+AS%22">Wolberg AS</searchLink>; Department of Pathology and Laboratory Medicine and UNC Blood Research Center, University of North Carolina at Chapel Hill, NC, 27599, USA.<br /><searchLink fieldCode="AU" term="%22Han+B%22">Han B</searchLink>; Department of Mechanical Science and Engineering, University of Illinois Urbana-Champaign, Urbana, IL, 61801, USA; Cancer Center at Illinois, University of Illinois Urbana-Champaign, Urbana, IL, 61801, USA; Chan Zuckerberg Biohub Chicago, Chicago, IL, 60642, USA; Department of Bioengineering, Materials Research Laboratory, Institute of Genomic Biology and Beckman Institute, University of Illinois Urbana-Champaign, Urbana, IL, 61801, USA. Electronic address: bumsooh@illinois.edu.
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              Text: 2026 Apr
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