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Effectiveness and Safety of Low-Sodium Oxybate in Participants with Idiopathic Hypersomnia: Primary Results from the DUET Study.

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Title: Effectiveness and Safety of Low-Sodium Oxybate in Participants with Idiopathic Hypersomnia: Primary Results from the DUET Study.
Authors: Plante DT; Department of Psychiatry, University of Wisconsin, Madison, 6001 Research Park Blvd, Madison, WI, 53719, USA. dplante@wisc.edu., Cairns A; Jazz Pharmaceuticals, Philadelphia, PA, USA., Schneider LD; Stanford Sleep Medicine Center, Redwood City, CA, USA., Nichols DA; Jazz Pharmaceuticals, Palo Alto, CA, USA., Steininger TL; Jazz Pharmaceuticals, Palo Alto, CA, USA., Fuller DS; Jazz Pharmaceuticals, Philadelphia, PA, USA., Kirby MT; Jazz Pharmaceuticals, Philadelphia, PA, USA.; Department of Psychiatry, Medical College of Georgia at Augusta University, Augusta, GA, USA., Akerman S; Jazz Pharmaceuticals, Philadelphia, PA, USA., Alexander JK; Jazz Pharmaceuticals, Palo Alto, CA, USA., Whalen M; Jazz Pharmaceuticals, Philadelphia, PA, USA., Ruoff CM; Mayo Clinic, Scottsdale, AZ, USA.
Source: CNS drugs [CNS Drugs] 2026 Jun; Vol. 40 (6), pp. 803-822. Date of Electronic Publication: 2026 Mar 14.
Publication Type: Journal Article; Multicenter Study; Clinical Trial, Phase IV; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Adis, Springer International Country of Publication: New Zealand NLM ID: 9431220 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1179-1934 (Electronic) Linking ISSN: 11727047 NLM ISO Abbreviation: CNS Drugs Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Effectiveness and Safety of Low-Sodium Oxybate in Participants with Idiopathic Hypersomnia: Primary Results from the DUET Study.
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  Data: <searchLink fieldCode="AU" term="%22Plante+DT%22">Plante DT</searchLink>; Department of Psychiatry, University of Wisconsin, Madison, 6001 Research Park Blvd, Madison, WI, 53719, USA. dplante@wisc.edu.<br /><searchLink fieldCode="AU" term="%22Cairns+A%22">Cairns A</searchLink>; Jazz Pharmaceuticals, Philadelphia, PA, USA.<br /><searchLink fieldCode="AU" term="%22Schneider+LD%22">Schneider LD</searchLink>; Stanford Sleep Medicine Center, Redwood City, CA, USA.<br /><searchLink fieldCode="AU" term="%22Nichols+DA%22">Nichols DA</searchLink>; Jazz Pharmaceuticals, Palo Alto, CA, USA.<br /><searchLink fieldCode="AU" term="%22Steininger+TL%22">Steininger TL</searchLink>; Jazz Pharmaceuticals, Palo Alto, CA, USA.<br /><searchLink fieldCode="AU" term="%22Fuller+DS%22">Fuller DS</searchLink>; Jazz Pharmaceuticals, Philadelphia, PA, USA.<br /><searchLink fieldCode="AU" term="%22Kirby+MT%22">Kirby MT</searchLink>; Jazz Pharmaceuticals, Philadelphia, PA, USA.; Department of Psychiatry, Medical College of Georgia at Augusta University, Augusta, GA, USA.<br /><searchLink fieldCode="AU" term="%22Akerman+S%22">Akerman S</searchLink>; Jazz Pharmaceuticals, Philadelphia, PA, USA.<br /><searchLink fieldCode="AU" term="%22Alexander+JK%22">Alexander JK</searchLink>; Jazz Pharmaceuticals, Palo Alto, CA, USA.<br /><searchLink fieldCode="AU" term="%22Whalen+M%22">Whalen M</searchLink>; Jazz Pharmaceuticals, Philadelphia, PA, USA.<br /><searchLink fieldCode="AU" term="%22Ruoff+CM%22">Ruoff CM</searchLink>; Mayo Clinic, Scottsdale, AZ, USA.
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  Data: <searchLink fieldCode="JN" term="%229431220%22">CNS drugs</searchLink> [CNS Drugs] 2026 Jun; Vol. 40 (6), pp. 803-822. <i>Date of Electronic Publication: </i>2026 Mar 14.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Adis%2C+Springer+International%22">Adis, Springer International </searchLink><i>Country of Publication: </i>New Zealand <i>NLM ID: </i>9431220 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1179-1934 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2211727047%22">11727047 </searchLink><i>NLM ISO Abbreviation: </i>CNS Drugs <i>Subsets: </i>MEDLINE
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              Text: 2026 Jun
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